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May 2002 (Volume 50, Number 5). [Index by author]

	(Cover illustration)	Leading articles Digest Commentaries Clinical @lert Helicobacter pylori Endoscopy Small intestine Colorectal cancer Biliary tract Pancreatitis Liver disease Occasional reports Case reports Reviews Letters Corrections Electronic pages

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Leading articles

Non-alcoholic steatohepatitis (NASH): where are we now and where are we going?
C P Day
Gut 2002; 50: 585-588. doi:10.1136/gut.50.5.585 [Abstract] [Full text] [PDF] [Request Permissions]

Digest

Digest
Ian Forgacs
Gut 2002; 50: 585. doi:10.1136/gut.50.5.585-a [Extract] [Full text] [PDF] [Request Permissions]

Commentaries

Aspirin injury and H pylori
A Schmassmann
Gut 2002; 50: 589-590. doi:10.1136/gut.50.5.589 [Extract] [Full text] [PDF] [Request Permissions]

The SPINK in chronic pancreatitis: similar finds, different minds
H Witt
Gut 2002; 50: 590-591. doi:10.1136/gut.50.5.590 [Extract] [Full text] [PDF] [Request Permissions]

Clinical @lert

Should abnormal oesophageal motility in gastro-oesophageal reflux disease (GORD) influence decisions about fundoplication?
R C Heading
Gut 2002; 50: 592-593. doi:10.1136/gut.50.5.592 [Extract] [Full text] [PDF] [Request Permissions]

Helicobacter pylori

Helicobacter pylori infection potentiates aspirin induced gastric mucosal injury in Mongolian gerbils
N Yoshida, N Sugimoto, F Hirayama, Y Nakamura, H Ichikawa, Y Naito, and T Yoshikawa
Gut 2002; 50: 594-598. doi:10.1136/gut.50.5.594 [Abstract] [Full text] [PDF] [Request Permissions]

Endoscopy

You get what you expect? A critical appraisal of imaging methodology in endosonographic cancer staging
A Meining, H J Dittler, A Wolf, R Lorenz, V Schusdziarra, J-R Siewert, M Classen, H Höfler, and T Rösch
Gut 2002; 50: 599-603. doi:10.1136/gut.50.5.599 [Abstract] [Full text] [PDF] [Request Permissions]

NORCCAP (Norwegian colorectal cancer prevention): a randomised trial to assess the safety and efficacy of carbon dioxide versus air insufflation in colonoscopy
M Bretthauer, E Thiis-Evensen, G Huppertz-Hauss, L Gisselsson, T Grotmol, E Skovlund, and G Hoff
Gut 2002; 50: 604-607. doi:10.1136/gut.50.5.604 [Abstract] [Full text] [PDF] [Request Permissions]

Small intestine

Lack of simian immunodeficiency virus (SIV) specific IgA response in the intestine of SIV infected rhesus macaques
F Schäfer, S Kewenig, N Stolte, C Stahl-Hennig, A Stallmach, F-J Kaup, M Zeitz, and T Schneider
Gut 2002; 50: 608-614. doi:10.1136/gut.50.5.608 [Abstract] [Full text] [PDF] [Request Permissions]

Recovery of ischaemic injured porcine ileum: evidence for a contributory role of COX-1 and COX-2
A T Blikslager, D N Zimmel, K M Young, N B Campbell, D Little, and R A Argenzio
Gut 2002; 50: 615-623. doi:10.1136/gut.50.5.615 [Abstract] [Full text] [PDF] [Request Permissions]

The first large population based twin study of coeliac disease
L Greco, R Romino, I Coto, N Di Cosmo, S Percopo, M Maglio, F Paparo, V Gasperi, M G Limongelli, R Cotichini, C D'Agate, N Tinto, L Sacchetti, R Tosi, and M A Stazi
Gut 2002; 50: 624-628. doi:10.1136/gut.50.5.624 [Abstract] [Full text] [PDF] [Request Permissions]

Neutrophil migration into indomethacin induced rat small intestinal injury is CD11a/CD18 and CD11b/CD18 co-dependent
A W Stadnyk, C Dollard, T B Issekutz, and A C Issekutz
Gut 2002; 50: 629-635. doi:10.1136/gut.50.5.629 [Abstract] [Full text] [PDF] [Request Permissions]

Colorectal cancer

Duodenal cancer in patients with familial adenomatous polyposis (FAP): results of a 10 year prospective study
C J Groves, B P Saunders, A D Spigelman, and R K S Phillips
Gut 2002; 50: 636-641. doi:10.1136/gut.50.5.636 [Abstract] [Full text] [PDF] [Request Permissions]

Plasma insulin-like growth factor 1, insulin-like growth factor binding protein 3, and risk of colorectal cancer: a prospective study in northern Sweden
R Palmqvist, G Hallmans, S Rinaldi, C Biessy, R Stenling, E Riboli, and R Kaaks
Gut 2002; 50: 642-646. doi:10.1136/gut.50.5.642 [Abstract] [Full text] [PDF] [Request Permissions]

The risk of subsequent primary cancers after colorectal cancer in southeast England
H S Evans, H Møller, D Robinson, C M Lewis, C M J Bell, and S V Hodgson
Gut 2002; 50: 647-652. doi:10.1136/gut.50.5.647 [Abstract] [Full text] [PDF] [Request Permissions]

Family history of cancer and germline BRCA2 mutations in sporadic exocrine pancreatic cancer
F X Real, N Malats, G Lesca, M Porta, S Chopin, G M Lenoir, and O Sinilnikova
Gut 2002; 50: 653-657. doi:10.1136/gut.50.5.653 [Abstract] [Full text] [PDF] [Request Permissions]

Characteristics of the peroxisome proliferator activated receptor ${gamma}$ (PPAR ${gamma}$ ) ligand induced apoptosis in colon cancer cells
T Shimada, K Kojima, K Yoshiura, H Hiraishi, and A Terano
Gut 2002; 50: 658-664. doi:10.1136/gut.50.5.658 [Abstract] [Full text] [PDF] [Request Permissions]

Biliary tract

Outcome of endoscopic sphincterotomy in post cholecystectomy patients with sphincter of Oddi dysfunction as predicted by manometry and quantitative choledochoscintigraphy
M Cicala, F I Habib, P Vavassori, N Pallotta, O Schillaci, G Costamagna, M P L Guarino, F Scopinaro, F Fiocca, A Torsoli, and E Corazziari
Gut 2002; 50: 665-668. doi:10.1136/gut.50.5.665 [Abstract] [Full text] [PDF] [Request Permissions]

Intraduodenal conjugated bile salts exert negative feedback control on gall bladder emptying in the fasting state without affecting cholecystokinin release or antroduodenal motility
N A M van Ooteghem, A Moschetta, J F Rehfeld, M Samsom, K J van Erpecum, and G P van Berge-Henegouwen
Gut 2002; 50: 669-674. doi:10.1136/gut.50.5.669 [Abstract] [Full text] [PDF] [Request Permissions]

Pancreatitis

The N34S mutation of SPINK1 (PSTI) is associated with a familial pattern of idiopathic chronic pancreatitis but does not cause the disease
J Threadgold, W Greenhalf, I Ellis, N Howes, M M Lerch, P Simon, J Jansen, R Charnley, R Laugier, L Frulloni, A Oláh, M Delhaye, I Ihse, O B Schaffalitzky de Muckadell, Å Andrén-Sandberg, C W Imrie, J Martinek, T M Gress, R Mountford, D Whitcomb, and J P Neoptolemos
Gut 2002; 50: 675-681. doi:10.1136/gut.50.5.675 [Abstract] [Full text] [PDF] [Request Permissions]

Neural alterations in surgical stage chronic pancreatitis are independent of the underlying aetiology
H Friess, S Shrikhande, M Shrikhande, M Martignoni, C Kulli, A Zimmermann, A Kappeler, H Ramesh, and M Büchler
Gut 2002; 50: 682-686. doi:10.1136/gut.50.5.682 [Abstract] [Full text] [PDF] [Request Permissions]

Mutations in serine protease inhibitor Kazal type 1 are strongly associated with chronic pancreatitis
J P H Drenth, R te Morsche, and J B M J Jansen
Gut 2002; 50: 687-692. doi:10.1136/gut.50.5.687 [Abstract] [Full text] [PDF] [Request Permissions]

Liver disease

Infection rate and spontaneous seroreversion of anti-hepatitis C virus during the natural course of hepatitis C virus infection in the general population
L A Kondili, P Chionne, A Costantino, U Villano, C Lo Noce, F Pannozzo, A Mele, S Giampaoli, and M Rapicetta
Gut 2002; 50: 693-696. doi:10.1136/gut.50.5.693 [Abstract] [Full text] [PDF] [Request Permissions]

Histology predicts cirrhotic evolution of post transplant hepatitis C
M Guido, S Fagiuoli, G Tessari, P Burra, G Leandro, P Boccagni, U Cillo, R Naccarato, and M Rugge
Gut 2002; 50: 697-700. doi:10.1136/gut.50.5.697 [Abstract] [Full text] [PDF] [Request Permissions]

Effect of ursodeoxycholic acid on methionine adenosyltransferase activity and hepatic glutathione metabolism in rats
C M Rodríguez-Ortigosa, R N Cincu, S Sanz, F Ruiz, J Quiroga, and J Prieto
Gut 2002; 50: 701-706. doi:10.1136/gut.50.5.701 [Abstract] [Full text] [PDF] [Request Permissions]

Impaired tuftsin activity in cirrhosis: relationship with splenic function and clinical outcome
F Trevisani, E Castelli, F G Foschi, M Parazza, E Loggi, M Bertelli, C Melotti, M Domenicali, G Zoli, and M Bernardi
Gut 2002; 50: 707-712. doi:10.1136/gut.50.5.707 [Abstract] [Full text] [PDF] [Request Permissions]

Characteristics of autoimmune hepatitis in patients who are not of European Caucasoid ethnic origin
T Zolfino, M A Heneghan, S Norris, P M Harrison, B C Portmann, and I G McFarlane
Gut 2002; 50: 713-717. doi:10.1136/gut.50.5.713 [Abstract] [Full text] [PDF] [Request Permissions]

Percutaneous evacuation (PEVAC) of multivesicular echinococcal cysts with or without cystobiliary fistulas which contain non-drainable material: first results of a modified PAIR method
H G Schipper, J S Laméris, O M van Delden, E A Rauws, and P A Kager
Gut 2002; 50: 718-723. doi:10.1136/gut.50.5.718 [Abstract] [Full text] [PDF] [Request Permissions]

Occasional reports

A survey on gastroenterology training in Europe
R Bisschops, A Wilmer, and J Tack
Gut 2002; 50: 724-729. doi:10.1136/gut.50.5.724 [Abstract] [Full text] [Web-only long version] [PDF] [Request Permissions]

Case reports

Role of alpha-1-antichymotrypsin deficiency in promoting cirrhosis in two siblings with heterozygous alpha-1-antitrypsin deficiency phenotype SZ
D Yoon, F Kueppers, R M Genta, G B Klintmalm, V I Khaoustov, and B Yoffe
Gut 2002; 50: 730-732. doi:10.1136/gut.50.5.730 [Abstract] [Full text] [PDF] [Request Permissions]

Reviews

Ablative therapy for liver tumours
E A Dick, S D Taylor-Robinson, H C Thomas, and W M W Gedroyc
Gut 2002; 50: 733-739. doi:10.1136/gut.50.5.733 [Abstract] [Full text] [PDF] [Request Permissions]

Letters

Intestinal intraepithelial lymphocytes and anti-transglutaminase in a screening algorithm for coeliac disease
F Leon, P Eiras, G Roy, and C Camarero
Gut 2002; 50: 740-741. doi:10.1136/gut.50.5.740 [Extract] [Full text] [PDF] [Request Permissions]

The changing scope of colorectal cancer
J S White, K Mc Callion, K R Gardiner, R M S Mitchell, RG P Watson, J S A Collins, R H Wilson, and F Kee
Gut 2002; 50: 741. doi:10.1136/gut.50.5.741 [Extract] [Full text] [PDF] [Request Permissions]

A Paneth cell surrogate?
C A Rubio
Gut 2002; 50: 741-742. doi:10.1136/gut.50.5.741-a [Extract] [Full text] [PDF] [Request Permissions]

Corrections

Correction
Gut 2002; 50: 742. doi:10.1136/gut.50.5.742 [Extract] [Full text] [PDF] [Request Permissions]

Electronic pages

Abstracts from the British Association for the Study of the Liver Meeting Held on 13–14 September 2001 at the Royal Free Hospital, London, UK
Gut 2002; 50: e1-e27. doi:10.1136/gut.50.5.e1 [Extract] [Full text] [PDF] [Request Permissions]

Cover

Vertically oriented double magnet configuration. (From the review by Dick et al , pp 733-739.)

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	Non-alcoholic steatohepatitis (NASH): where are we now and where are we going? C P Day Gut 2002; 50: 585-588. doi:10.1136/gut.50.5.585 [Abstract] [Full text] [PDF] [Request Permissions]

	Digest Ian Forgacs Gut 2002; 50: 585. doi:10.1136/gut.50.5.585-a [Extract] [Full text] [PDF] [Request Permissions]

	Aspirin injury and H pylori A Schmassmann Gut 2002; 50: 589-590. doi:10.1136/gut.50.5.589 [Extract] [Full text] [PDF] [Request Permissions]

	The SPINK in chronic pancreatitis: similar finds, different minds H Witt Gut 2002; 50: 590-591. doi:10.1136/gut.50.5.590 [Extract] [Full text] [PDF] [Request Permissions]

	Should abnormal oesophageal motility in gastro-oesophageal reflux disease (GORD) influence decisions about fundoplication? R C Heading Gut 2002; 50: 592-593. doi:10.1136/gut.50.5.592 [Extract] [Full text] [PDF] [Request Permissions]

	Helicobacter pylori infection potentiates aspirin induced gastric mucosal injury in Mongolian gerbils N Yoshida, N Sugimoto, F Hirayama, Y Nakamura, H Ichikawa, Y Naito, and T Yoshikawa Gut 2002; 50: 594-598. doi:10.1136/gut.50.5.594 [Abstract] [Full text] [PDF] [Request Permissions]

	You get what you expect? A critical appraisal of imaging methodology in endosonographic cancer staging A Meining, H J Dittler, A Wolf, R Lorenz, V Schusdziarra, J-R Siewert, M Classen, H Höfler, and T Rösch Gut 2002; 50: 599-603. doi:10.1136/gut.50.5.599 [Abstract] [Full text] [PDF] [Request Permissions]

	NORCCAP (Norwegian colorectal cancer prevention): a randomised trial to assess the safety and efficacy of carbon dioxide versus air insufflation in colonoscopy M Bretthauer, E Thiis-Evensen, G Huppertz-Hauss, L Gisselsson, T Grotmol, E Skovlund, and G Hoff Gut 2002; 50: 604-607. doi:10.1136/gut.50.5.604 [Abstract] [Full text] [PDF] [Request Permissions]

	Lack of simian immunodeficiency virus (SIV) specific IgA response in the intestine of SIV infected rhesus macaques F Schäfer, S Kewenig, N Stolte, C Stahl-Hennig, A Stallmach, F-J Kaup, M Zeitz, and T Schneider Gut 2002; 50: 608-614. doi:10.1136/gut.50.5.608 [Abstract] [Full text] [PDF] [Request Permissions]

	Recovery of ischaemic injured porcine ileum: evidence for a contributory role of COX-1 and COX-2 A T Blikslager, D N Zimmel, K M Young, N B Campbell, D Little, and R A Argenzio Gut 2002; 50: 615-623. doi:10.1136/gut.50.5.615 [Abstract] [Full text] [PDF] [Request Permissions]

	The first large population based twin study of coeliac disease L Greco, R Romino, I Coto, N Di Cosmo, S Percopo, M Maglio, F Paparo, V Gasperi, M G Limongelli, R Cotichini, C D'Agate, N Tinto, L Sacchetti, R Tosi, and M A Stazi Gut 2002; 50: 624-628. doi:10.1136/gut.50.5.624 [Abstract] [Full text] [PDF] [Request Permissions]

	Neutrophil migration into indomethacin induced rat small intestinal injury is CD11a/CD18 and CD11b/CD18 co-dependent A W Stadnyk, C Dollard, T B Issekutz, and A C Issekutz Gut 2002; 50: 629-635. doi:10.1136/gut.50.5.629 [Abstract] [Full text] [PDF] [Request Permissions]

	Duodenal cancer in patients with familial adenomatous polyposis (FAP): results of a 10 year prospective study C J Groves, B P Saunders, A D Spigelman, and R K S Phillips Gut 2002; 50: 636-641. doi:10.1136/gut.50.5.636 [Abstract] [Full text] [PDF] [Request Permissions]

	Plasma insulin-like growth factor 1, insulin-like growth factor binding protein 3, and risk of colorectal cancer: a prospective study in northern Sweden R Palmqvist, G Hallmans, S Rinaldi, C Biessy, R Stenling, E Riboli, and R Kaaks Gut 2002; 50: 642-646. doi:10.1136/gut.50.5.642 [Abstract] [Full text] [PDF] [Request Permissions]

	The risk of subsequent primary cancers after colorectal cancer in southeast England H S Evans, H Møller, D Robinson, C M Lewis, C M J Bell, and S V Hodgson Gut 2002; 50: 647-652. doi:10.1136/gut.50.5.647 [Abstract] [Full text] [PDF] [Request Permissions]

	Family history of cancer and germline BRCA2 mutations in sporadic exocrine pancreatic cancer F X Real, N Malats, G Lesca, M Porta, S Chopin, G M Lenoir, and O Sinilnikova Gut 2002; 50: 653-657. doi:10.1136/gut.50.5.653 [Abstract] [Full text] [PDF] [Request Permissions]

	Characteristics of the peroxisome proliferator activated receptor ${gamma}$ (PPAR ${gamma}$ ) ligand induced apoptosis in colon cancer cells T Shimada, K Kojima, K Yoshiura, H Hiraishi, and A Terano Gut 2002; 50: 658-664. doi:10.1136/gut.50.5.658 [Abstract] [Full text] [PDF] [Request Permissions]

	Outcome of endoscopic sphincterotomy in post cholecystectomy patients with sphincter of Oddi dysfunction as predicted by manometry and quantitative choledochoscintigraphy M Cicala, F I Habib, P Vavassori, N Pallotta, O Schillaci, G Costamagna, M P L Guarino, F Scopinaro, F Fiocca, A Torsoli, and E Corazziari Gut 2002; 50: 665-668. doi:10.1136/gut.50.5.665 [Abstract] [Full text] [PDF] [Request Permissions]

	Intraduodenal conjugated bile salts exert negative feedback control on gall bladder emptying in the fasting state without affecting cholecystokinin release or antroduodenal motility N A M van Ooteghem, A Moschetta, J F Rehfeld, M Samsom, K J van Erpecum, and G P van Berge-Henegouwen Gut 2002; 50: 669-674. doi:10.1136/gut.50.5.669 [Abstract] [Full text] [PDF] [Request Permissions]

	The N34S mutation of SPINK1 (PSTI) is associated with a familial pattern of idiopathic chronic pancreatitis but does not cause the disease J Threadgold, W Greenhalf, I Ellis, N Howes, M M Lerch, P Simon, J Jansen, R Charnley, R Laugier, L Frulloni, A Oláh, M Delhaye, I Ihse, O B Schaffalitzky de Muckadell, Å Andrén-Sandberg, C W Imrie, J Martinek, T M Gress, R Mountford, D Whitcomb, and J P Neoptolemos Gut 2002; 50: 675-681. doi:10.1136/gut.50.5.675 [Abstract] [Full text] [PDF] [Request Permissions]

	Neural alterations in surgical stage chronic pancreatitis are independent of the underlying aetiology H Friess, S Shrikhande, M Shrikhande, M Martignoni, C Kulli, A Zimmermann, A Kappeler, H Ramesh, and M Büchler Gut 2002; 50: 682-686. doi:10.1136/gut.50.5.682 [Abstract] [Full text] [PDF] [Request Permissions]

	Mutations in serine protease inhibitor Kazal type 1 are strongly associated with chronic pancreatitis J P H Drenth, R te Morsche, and J B M J Jansen Gut 2002; 50: 687-692. doi:10.1136/gut.50.5.687 [Abstract] [Full text] [PDF] [Request Permissions]

	Infection rate and spontaneous seroreversion of anti-hepatitis C virus during the natural course of hepatitis C virus infection in the general population L A Kondili, P Chionne, A Costantino, U Villano, C Lo Noce, F Pannozzo, A Mele, S Giampaoli, and M Rapicetta Gut 2002; 50: 693-696. doi:10.1136/gut.50.5.693 [Abstract] [Full text] [PDF] [Request Permissions]

	Histology predicts cirrhotic evolution of post transplant hepatitis C M Guido, S Fagiuoli, G Tessari, P Burra, G Leandro, P Boccagni, U Cillo, R Naccarato, and M Rugge Gut 2002; 50: 697-700. doi:10.1136/gut.50.5.697 [Abstract] [Full text] [PDF] [Request Permissions]

	Effect of ursodeoxycholic acid on methionine adenosyltransferase activity and hepatic glutathione metabolism in rats C M Rodríguez-Ortigosa, R N Cincu, S Sanz, F Ruiz, J Quiroga, and J Prieto Gut 2002; 50: 701-706. doi:10.1136/gut.50.5.701 [Abstract] [Full text] [PDF] [Request Permissions]

	Impaired tuftsin activity in cirrhosis: relationship with splenic function and clinical outcome F Trevisani, E Castelli, F G Foschi, M Parazza, E Loggi, M Bertelli, C Melotti, M Domenicali, G Zoli, and M Bernardi Gut 2002; 50: 707-712. doi:10.1136/gut.50.5.707 [Abstract] [Full text] [PDF] [Request Permissions]

	Characteristics of autoimmune hepatitis in patients who are not of European Caucasoid ethnic origin T Zolfino, M A Heneghan, S Norris, P M Harrison, B C Portmann, and I G McFarlane Gut 2002; 50: 713-717. doi:10.1136/gut.50.5.713 [Abstract] [Full text] [PDF] [Request Permissions]

	Percutaneous evacuation (PEVAC) of multivesicular echinococcal cysts with or without cystobiliary fistulas which contain non-drainable material: first results of a modified PAIR method H G Schipper, J S Laméris, O M van Delden, E A Rauws, and P A Kager Gut 2002; 50: 718-723. doi:10.1136/gut.50.5.718 [Abstract] [Full text] [PDF] [Request Permissions]

	A survey on gastroenterology training in Europe R Bisschops, A Wilmer, and J Tack Gut 2002; 50: 724-729. doi:10.1136/gut.50.5.724 [Abstract] [Full text] [Web-only long version] [PDF] [Request Permissions]

	Role of alpha-1-antichymotrypsin deficiency in promoting cirrhosis in two siblings with heterozygous alpha-1-antitrypsin deficiency phenotype SZ D Yoon, F Kueppers, R M Genta, G B Klintmalm, V I Khaoustov, and B Yoffe Gut 2002; 50: 730-732. doi:10.1136/gut.50.5.730 [Abstract] [Full text] [PDF] [Request Permissions]

	Ablative therapy for liver tumours E A Dick, S D Taylor-Robinson, H C Thomas, and W M W Gedroyc Gut 2002; 50: 733-739. doi:10.1136/gut.50.5.733 [Abstract] [Full text] [PDF] [Request Permissions]

	Intestinal intraepithelial lymphocytes and anti-transglutaminase in a screening algorithm for coeliac disease F Leon, P Eiras, G Roy, and C Camarero Gut 2002; 50: 740-741. doi:10.1136/gut.50.5.740 [Extract] [Full text] [PDF] [Request Permissions]

	The changing scope of colorectal cancer J S White, K Mc Callion, K R Gardiner, R M S Mitchell, RG P Watson, J S A Collins, R H Wilson, and F Kee Gut 2002; 50: 741. doi:10.1136/gut.50.5.741 [Extract] [Full text] [PDF] [Request Permissions]

	A Paneth cell surrogate? C A Rubio Gut 2002; 50: 741-742. doi:10.1136/gut.50.5.741-a [Extract] [Full text] [PDF] [Request Permissions]

	Correction Gut 2002; 50: 742. doi:10.1136/gut.50.5.742 [Extract] [Full text] [PDF] [Request Permissions]

	Abstracts from the British Association for the Study of the Liver Meeting Held on 13–14 September 2001 at the Royal Free Hospital, London, UK Gut 2002; 50: e1-e27. doi:10.1136/gut.50.5.e1 [Extract] [Full text] [PDF] [Request Permissions]