Leading articles

	Dysbiosis in inflammatory bowel disease C P Tamboli, C Neut, P Desreumaux, and J F Colombel Gut 2004; 53: 1-4. doi:10.1136/gut.53.1.1 [Abstract] [Full text] [PDF] [Request Permissions]

Digest

	Digest Robin Spiller Gut 2004; 53: 1. doi:10.1136/gut.53.1.1-a [Extract] [Full text] [PDF] [Request Permissions]

GI snapshot

	Self inflicted rectal ulcer: hearing is believing A Hokama, F Kinjo, R Tomiyama, A Saito, H Kikkawa, and H Miyazato Gut 2004; 53: 4. doi:10.1136/gut.53.1.4 [Extract] [Full text] [PDF] [Request Permissions]
	GI SNAPSHOT Gut 2004; 53: 20. doi:10.1136/gut.53.1.20 [Extract] [Full text] [PDF] [Request Permissions]

Commentaries

	Helicobacter pylori infection and long term proton pump inhibitor therapy K E L McColl Gut 2004; 53: 5-7. doi:10.1136/gut.53.1.5 [Extract] [Full text] [PDF] [Request Permissions]
	Helminths and harmony J V Weinstock, R Summers, and D E Elliott Gut 2004; 53: 7-9. doi:10.1136/gut.53.1.7 [Extract] [Full text] [PDF] [Request Permissions]
	Do steroids ameliorate bile acid malabsorption in Crohn’s disease? R S Kwon and M C Carey Gut 2004; 53: 10-11. doi:10.1136/gut.53.1.10 [Extract] [Full text] [PDF] [Request Permissions]

Oesophagus

	Cure of Helicobacter pylori infection in patients with reflux oesophagitis treated with long term omeprazole reverses gastritis without exacerbation of reflux disease: results of a randomised controlled trial E J Kuipers, G F Nelis, E C Klinkenberg-Knol, P Snel, D Goldfain, J J Kolkman, H P M Festen, J Dent, P Zeitoun, N Havu, M Lamm, and A Walan Gut 2004; 53: 12-20. doi:10.1136/gut.53.1.12 [Abstract] [Full text] [PDF] [Request Permissions]
	Oesophageal clearance of acid and bile: a combined radionuclide, pH, and Bilitec study G H Koek, R Vos, P Flamen, D Sifrim, F Lammert, B Vanbilloen, J Janssens, and J Tack Gut 2004; 53: 21-26. doi:10.1136/gut.53.1.21 [Abstract] [Full text] [PDF] [Request Permissions]
	Expression of cyclooxygenase 2, microsomal prostaglandin E synthase 1, and EP receptors is increased in rat oesophageal squamous cell dysplasia and Barrett’s metaplasia induced by duodenal contents reflux T J Jang, S K Min, J D Bae, K H Jung, J I Lee, J R Kim, and W S Ahn Gut 2004; 53: 27-33. doi:10.1136/gut.53.1.27 [Abstract] [Full text] [PDF] [Request Permissions]

Stomach

	Long term outcome of patients with gastric marginal zone B cell lymphoma of mucosa associated lymphoid tissue (MALT) following exclusive Helicobacter pylori eradication therapy: experience from a large prospective series W Fischbach, M-E Goebeler-Kolve, B Dragosics, A Greiner, and M Stolte Gut 2004; 53: 34-37. doi:10.1136/gut.53.1.34 [Abstract] [Full text] [PDF] [Request Permissions]

Small intestine

	Lysine kinetics in preterm infants: the importance of enteral feeding S R D van der Schoor, P J Reeds, F Stellaard, J D L Wattimena, P J J Sauer, H A Büller, and J B van Goudoever Gut 2004; 53: 38-43. doi:10.1136/gut.53.1.38 [Abstract] [Full text] [PDF] [Request Permissions]
	Ferroportin/IREG-1/MTP-1/SLC40A1 modulates the uptake of iron at the apical membrane of enterocytes C Thomas and P S Oates Gut 2004; 53: 44-49. doi:10.1136/gut.53.1.44 [Abstract] [Full text] [PDF] [Request Permissions]
	Intracellular potentiation between two second messenger systems may contribute to cholera toxin induced intestinal secretion in humans M R Banks, M Golder, M J G Farthing, and D E Burleigh Gut 2004; 53: 50-57. doi:10.1136/gut.53.1.50 [Abstract] [Full text] [PDF] [Request Permissions]
	A novel method for rapidly diagnosing the causes of diarrhoea C S J Probert, P R H Jones, and N M Ratcliffe Gut 2004; 53: 58-61. doi:10.1136/gut.53.1.58 [Abstract] [Full text] [PDF] [Request Permissions]
	Acute dehydrating disease caused by Vibrio cholerae serogroups O1 and O139 induce increases in innate cells and inflammatory mediators at the mucosal surface of the gut F Qadri, T R Bhuiyan, K K Dutta, R Raqib, M S Alam, N H Alam, A-M Svennerholm, and M M Mathan Gut 2004; 53: 62-69. doi:10.1136/gut.53.1.62 [Abstract] [Full text] [PDF] [Request Permissions]

Inflammatory bowel disease

	Defective mucosal T cell death is sustainably reverted by infliximab in a caspase dependent pathway in Crohn’s disease A Di Sabatino, R Ciccocioppo, B Cinque, D Millimaggi, R Morera, L Ricevuti, M G Cifone, and G R Corazza Gut 2004; 53: 70-77. doi:10.1136/gut.53.1.70 [Abstract] [Full text] [PDF] [Request Permissions]
	Human ileal bile acid transporter gene ASBT (SLC10A2) is transactivated by the glucocorticoid receptor D Jung, A C Fantin, U Scheurer, M Fried, and G A Kullak-Ublick Gut 2004; 53: 78-84. doi:10.1136/gut.53.1.78 [Abstract] [Full text] [PDF] [Request Permissions]
	Reversal of abnormal collagen production in Crohn’s disease intestinal biopsies treated with regenerating agents C Alexakis, J P Caruelle, A Sezeur, J Cosnes, J P Gendre, H Mosnier, L Beaugerie, D Gallot, M Malafosse, D Barritault, and P Kern Gut 2004; 53: 85-90. doi:10.1136/gut.53.1.85 [Abstract] [Full text] [PDF] [Request Permissions]
	Systemic antibodies towards mucosal bacteria in ulcerative colitis and Crohn’s disease differentially activate the innate immune response E Furrie, S Macfarlane, J H Cummings, and G T Macfarlane Gut 2004; 53: 91-98. doi:10.1136/gut.53.1.91 [Abstract] [Full text] [PDF] [Request Permissions]
	Concurrent infection with Schistosoma mansoni attenuates inflammation induced changes in colonic morphology, cytokine levels, and smooth muscle contractility of trinitrobenzene sulphonic acid induced colitis in rats T G Moreels, R J Nieuwendijk, J G De Man, B Y De Winter, A G Herman, E A Van Marck, and P A Pelckmans Gut 2004; 53: 99-107. doi:10.1136/gut.53.1.99 [Abstract] [Full text] [PDF] [Request Permissions]
	Once daily high dose probiotic therapy (VSL#3) for maintaining remission in recurrent or refractory pouchitis T Mimura, F Rizzello, U Helwig, G Poggioli, S Schreiber, I C Talbot, R J Nicholls, P Gionchetti, M Campieri, and M A Kamm Gut 2004; 53: 108-114. doi:10.1136/gut.53.1.108 [Abstract] [Full text] [PDF] [Request Permissions]

Colon

	Aetiology of colorectal cancer and relevance of monogenic inheritance M Ponz de Leon, P Benatti, F Borghi, M Pedroni, A Scarselli, C Di Gregorio, L Losi, A Viel, M Genuardi, G Abbati, G Rossi, M Menigatti, I Lamberti, G Ponti, and L Roncucci Gut 2004; 53: 115-122. doi:10.1136/gut.53.1.115 [Abstract] [Full text] [PDF] [Request Permissions]
	Regulation of epidermal growth factor receptor in human colon cancer cell lines by interferon J-L Yang, X-J Qu, P J Russell, and D Goldstein Gut 2004; 53: 123-129. doi:10.1136/gut.53.1.123 [Abstract] [Full text] [PDF] [Request Permissions]

Liver

	Randomised, double blind, placebo controlled trial of interferon, ribavirin, and amantadine versus interferon, ribavirin, and placebo in treatment naïve patients with chronic hepatitis C P J Thuluvath, A Maheshwari, J Mehdi, K D Fairbanks, L L-W Wu, L G Gelrud, M J Ryan, F A Anania, I F Lobis, and M Black Gut 2004; 53: 130-135. doi:10.1136/gut.53.1.130 [Abstract] [Full text] [PDF] [Request Permissions]
	Cholesterol synthesis inhibition distal to squalene upregulates biliary phospholipid secretion and counteracts cholelithiasis in the genetically prone C57L/J mouse G A Clarke, G Bouchard, B Paigen, and M C Carey Gut 2004; 53: 136-142. doi:10.1136/gut.53.1.136 [Abstract] [Full text] [PDF] [Request Permissions]

Occasional viewpoint

	Monitoring target reduction in hepatic venous pressure gradient during pharmacological therapy of portal hypertension: a close look at the evidence U Thalheimer, M Mela, D Patch, and A K Burroughs Gut 2004; 53: 143-148. doi:10.1136/gut.53.1.143 [Abstract] [Full text] [PDF] [Request Permissions]

Short report

	Undiagnosed coeliac disease does not appear to be associated with unfavourable outcome of pregnancy L Greco, A Veneziano, L Di Donato, C Zampella, M Pecoraro, D Paladini, F Paparo, A Vollaro, and P Martinelli Gut 2004; 53: 149-151. doi:10.1136/gut.53.1.149 [Abstract] [Full text] [PDF] [Request Permissions]

Conference report

	Westernisation of gastrointestinal diseases in Asia J J Y Sung Gut 2004; 53: 152. doi:10.1136/gut.53.1.152 [Abstract] [Full text] [PDF] [Request Permissions]

JournalScan

	JournalScan Gut 2004; 53: 153. doi:10.1136/gut.53.1.153 [Extract] [Full text] [PDF] [Request Permissions]

Letters

	Cyclooxygenase 2 selective inhibitor induced bowel stricture: a case report O Mir, R Dhote, R Scavennec, S Ropert, and B Christoforov Gut 2004; 53: 154. doi:10.1136/gut.53.1.154 [Extract] [Full text] [PDF] [Request Permissions]
	Should we screen adults with osteoporotic fractures for coeliac disease? A A Fisher, M W Davis, and M M Budge Gut 2004; 53: 154-155. doi:10.1136/gut.53.1.154-a [Extract] [Full text] [PDF] [Request Permissions]
	Mesalazine is safe for the treatment of IBD G D’Haens and A A van Bodegraven Gut 2004; 53: 155. doi:10.1136/gut.53.1.155 [Extract] [Full text] [PDF] [Request Permissions]
	Diet and colorectal cancer: fibre back on the menu? R P Arasaradnam, S A Riley, and B M Corfe Gut 2004; 53: 155-156. doi:10.1136/gut.53.1.155-a [Extract] [Full text] [PDF] [Request Permissions]
	Obesity as a risk factor for colorectal polyps in Japanese patients M Tashiro, T Akiyama, I Yoshikawa, K Kume, and M Otsuki Gut 2004; 53: 156. doi:10.1136/gut.53.1.156 [Extract] [Full text] [PDF] [Request Permissions]

Book reviews

	Colonic Diseases S Ghosh Gut 2004; 53: 156-157. doi:10.1136/gut.53.1.156-a [Extract] [Full text] [PDF] [Request Permissions]
	Inflammatory Bowel Disease: Diagnosis and Therapeutics S Ghosh Gut 2004; 53: 157. doi:10.1136/gut.53.1.157 [Extract] [Full text] [PDF] [Request Permissions]

Electronic pages

	Author index Gut 2004; 53: e1. doi:10.1136/gut.53.1.e1 [PDF] [Request Permissions]
	Subject index Gut 2004; 53: e2. doi:10.1136/gut.53.1.e2 [PDF] [Request Permissions]