Editorials

	Reflections on 2004 and plans for 2005 R C Spiller Gut 2004; 53: 1723. [Extract] [Full text] [PDF] [Request Permissions]

Digest

	Digest Robin Spiller Gut 2004; 53: 1723. [Extract] [Full text] [PDF] [Request Permissions]

Commentaries

	Increased gut permeability in Crohn’s disease: is TNF the link? P R Gibson Gut 2004; 53: 1724-1725. doi:10.1136/gut.2004.047092 [Extract] [Full text] [PDF] [Request Permissions]
	Recurrent bile duct stones after endoscopic sphincterotomy S Sultan and J Baillie Gut 2004; 53: 1725-1727. doi:10.1136/gut.2004.046185 [Extract] [Full text] [PDF] [Request Permissions]
	Molecular diagnosis of pancreatobiliary malignancies in brush cytologies of biliary strictures T M Gress Gut 2004; 53: 1727-1729. doi:10.1136/gut.2004.046177 [Extract] [Full text] [PDF] [Request Permissions]

Oesophagus

	Lifestyle related risk factors in the aetiology of gastro-oesophageal reflux M Nilsson, R Johnsen, W Ye, K Hveem, and J Lagergren Gut 2004; 53: 1730-1735. doi:10.1136/gut.2004.043265 [Abstract] [Full text] [PDF] [Request Permissions]
	What is the best management strategy for high grade dysplasia in Barrett’s oesophagus? A cost effectiveness analysis N J Shaheen, J M Inadomi, B F Overholt, and P Sharma Gut 2004; 53: 1736-1744. doi:10.1136/gut.2003.033837 [Abstract] [Full text] [PDF] [Request Permissions]
	Endoluminal gastroplication in children with significant gastro-oesophageal reflux disease M Thomson, A Fritscher-Ravens, S Hall, N Afzal, P Ashwood, and C P Swain Gut 2004; 53: 1745-1750. doi:10.1136/gut.2004.041921 [Abstract] [Full text] [PDF] [Request Permissions]

Miscellanea

	Brown spots in the bowel D R Gaya, A J Stanley, and A K Foulis Gut 2004; 53: 1744. doi:10.1136/gut.2004.039222 [Extract] [Full text] [PDF] [Request Permissions]
	Answer Gut 2004; 53: 1763. [Extract] [Full text] [PDF] [Request Permissions]
	Unexplained digestive bleeding in a cirrhotic patient S Evrard, O Le Moine, J Devière, P Yengue, N Nagy, M Adler, and A Van Gossum Gut 2004; 53: 1771. doi:10.1136/gut.2003.034611 [Extract] [Full text] [PDF] [Request Permissions]
	Answer Gut 2004; 53: 1780. [Extract] [Full text] [PDF] [Request Permissions]
	Complication of Waldenströem’s macroglobulinaemia following ERCP M Pascu, B Hanke, B Wiedenmann, F Martens, and A U Dignass Gut 2004; 53: 1793. doi:10.1136/gut.2003.031211 [Extract] [Full text] [PDF] [Request Permissions]
	Answer Gut 2004; 53: 1812. [Extract] [Full text] [PDF] [Request Permissions]
	An unusual case of colitis S Payne, M Phillips, D Reffitt, H Fidler, D Birch, D Joshi, J Norton, and J O’Donohue Gut 2004; 53: 1824. doi:10.1136/gut.2004.040451 [Extract] [Full text] [PDF] [Request Permissions]
	Answer Gut 2004; 53: 1849. [Extract] [Full text] [PDF] [Request Permissions]

Stomach

	Cyclooxygenase 1 is required for pH control at the mouse gastric surface H K Baumgartner, O T Starodub, J S Joehl, L Tackett, and M H Montrose Gut 2004; 53: 1751-1757. doi:10.1136/gut.2004.040238 [Abstract] [Full text] [PDF] [Request Permissions]
	Helicobacter pylori test and eradicate versus prompt endoscopy for management of dyspeptic patients: 6.7 year follow up of a randomised trial A T Lassen, J Hallas, and O B Schaffalitzky de Muckadell Gut 2004; 53: 1758-1763. doi:10.1136/gut.2004.043570 [Abstract] [Full text] [PDF] [Request Permissions]

Intestine

	Acetylated sialic acid residues and blood group antigens localise within the epithelium in microvillous atrophy indicating internal accumulation of the glycocalyx A D Phillips, A Brown, S Hicks, S Schüller, S H Murch, J A Walker-Smith, and D M Swallow Gut 2004; 53: 1764-1771. doi:10.1136/gut.2004.041954 [Abstract] [Full text] [PDF] [Request Permissions]
	Depletion of intestinal resident macrophages prevents ischaemia reperfusion injury in gut Y Chen, V C H Lui, N V Rooijen, and P K H Tam Gut 2004; 53: 1772-1780. doi:10.1136/gut.2003.034868 [Abstract] [Full text] [PDF] [Request Permissions]
	Citrulline increases arginine pools and restores nitrogen balance after massive intestinal resection S Osowska, C Moinard, C Loï, N Neveux, and L Cynober Gut 2004; 53: 1781-1786. doi:10.1136/gut.2004.042317 [Abstract] [Full text] [PDF] [Request Permissions]

Irritable bowel syndrome

	The role of tension receptors in colonic mechanosensitivity in humans M Corsetti, A-M Gevers, P Caenepeel, and J Tack Gut 2004; 53: 1787-1793. doi:10.1136/gut.2004.038786 [Abstract] [Full text] [PDF] [Request Permissions]
	Acute tryptophan depletion affects brain-gut responses in irritable bowel syndrome patients and controls T O C Kilkens, A Honig, M A van Nieuwenhoven, W J Riedel, and R-J M Brummer Gut 2004; 53: 1794-1800. doi:10.1136/gut.2004.041657 [Abstract] [Full text] [PDF] [Request Permissions]

Inflammatory bowel disease

	Human lymphocyte stimulation with pouchitis flora is greater than with flora from a healthy pouch but is suppressed by metronidazole A J G Bell, R J Nicholls, A Forbes, H J Ellis, and P J Ciclitira Gut 2004; 53: 1801-1805. doi:10.1136/gut.2003.026807 [Abstract] [Full text] [PDF] [Request Permissions]
	Clinical and subclinical intestinal inflammation assessed by the mucosal patch technique: studies of mucosal neutrophil and eosinophil activation in inflammatory bowel diseases and irritable bowel syndrome G Kristjánsson, P Venge, A Wanders, L Lööf, and R Hällgren Gut 2004; 53: 1806-1812. doi:10.1136/gut.2003.036418 [Abstract] [Full text] [PDF] [Request Permissions]
	Cancer surveillance in longstanding ulcerative colitis: endoscopic appearances help predict cancer risk M D Rutter, B P Saunders, K H Wilkinson, S Rumbles, G Schofield, M A Kamm, C B Williams, A B Price, I C Talbot, and A Forbes Gut 2004; 53: 1813-1816. doi:10.1136/gut.2003.038505 [Abstract] [Full text] [PDF] [Request Permissions]
	Increased epithelial uptake of protein antigens in the ileum of Crohn’s disease mediated by tumour necrosis factor J D Söderholm, C Streutker, P-C Yang, C Paterson, P K Singh, D M McKay, P M Sherman, K Croitoru, and M H Perdue Gut 2004; 53: 1817-1824. doi:10.1136/gut.2004.041426 [Abstract] [Full text] [PDF] [Request Permissions]

Colon cancer

	Effects of folylpolyglutamate synthetase modulation on chemosensitivity of colon cancer cells to 5-fluorouracil and methotrexate K-J Sohn, F Smirnakis, D N Moskovitz, P Novakovic, Z Yates, M Lucock, R Croxford, and Y-I Kim Gut 2004; 53: 1825-1831. doi:10.1136/gut.2004.042713 [Abstract] [Full text] [PDF] [Request Permissions]
	Evidence for genetic predisposition to desmoid tumours in familial adenomatous polyposis independent of the germline APC mutation N J H Sturt, M C Gallagher, P Bassett, C R Philp, K F Neale, I P M Tomlinson, A R J Silver, and R K S Phillips Gut 2004; 53: 1832-1836. doi:10.1136/gut.2004.042705 [Abstract] [Full text] [PDF] [Request Permissions]

Liver

	Bile secretory function in the obese Zucker rat: evidence of cholestasis and altered canalicular transport function M Pizarro, N Balasubramaniyan, N Solís, A Solar, I Duarte, J F Miquel, F J Suchy, M Trauner, L Accatino, M Ananthanarayanan, and M Arrese Gut 2004; 53: 1837-1843. doi:10.1136/gut.2003.037689 [Abstract] [Full text] [PDF] [Request Permissions]
	Tezosentan, an endothelin receptor antagonist, limits liver injury in endotoxin challenged cirrhotic rats W Urbanowicz, P Sogni, R Moreau, K A Tazi, E Barriere, O Poirel, A Martin, M C Guimont, D Cazals-Hatem, and D Lebrec Gut 2004; 53: 1844-1849. doi:10.1136/gut.2003.036517 [Abstract] [Full text] [PDF] [Request Permissions]
	Influence of biliary cirrhosis on the detoxification and elimination of a food derived carcinogen C G Dietrich, A Geier, H E Wasmuth, S Matern, C Gartung, D R de Waart, and R P J O Elferink Gut 2004; 53: 1850-1855. doi:10.1136/gut.2003.037507 [Abstract] [Full text] [PDF] [Request Permissions]

Pancreas and biliary

	Endoscopic retreatment of recurrent choledocholithiasis after sphincterotomy M Sugiyama, Y Suzuki, N Abe, T Masaki, T Mori, and Y Atomi Gut 2004; 53: 1856-1859. doi:10.1136/gut.2004.041020 [Abstract] [Full text] [PDF] [Request Permissions]
	Use of microsatellite marker loss of heterozygosity in accurate diagnosis of pancreaticobiliary malignancy from brush cytology samples A Khalid, R Pal, E Sasatomi, P Swalsky, A Slivka, D Whitcomb, and S Finkelstein Gut 2004; 53: 1860-1865. doi:10.1136/gut.2004.039784 [Abstract] [Full text] [PDF] [Request Permissions]

Recent advances in clinical practice

	Role of video endoscopy in managing small bowel disease P Swain and A Fritscher-Ravens Gut 2004; 53: 1866-1875. doi:10.1136/gut.2003.035576 [Extract] [Full text] [PDF] [Request Permissions]

JournalScan

	JournalScan Gut 2004; 53: 1876. [Extract] [Full text] [PDF] [Request Permissions]

Letters

	Should we remove all lesions at colonoscopy? • Author’s reply B Rembacken and D P Hurlstone Gut 2004; 53: 1877-1878. [Extract] [Full text] [PDF] [Request Permissions]
	Liver fibrosis: natural history may be affected by the biopsy sample • Author’s reply M Guido, M Rugge, and S D Ryder Gut 2004; 53: 1878. [Extract] [Full text] [PDF] [Request Permissions]
	Ultrastructural changes in enterocytes in subjects with Hashimoto’s thyroiditis F C Sasso, O Carbonara, R Torella, A Mezzogiorno, V Esposito, L deMagistris, M Secondulfo, R Carratu’, D Iafusco, and M Cartenì Gut 2004; 53: 1878-1880. doi:10.1136/gut.2004.047498 [Extract] [Full text] [PDF] [Request Permissions]

Book reviews

	Inflammatory Bowel Disease: From Bench to Bedside, 2nd edn S Ghosh Gut 2004; 53: 1880. [Extract] [Full text] [PDF] [Request Permissions]
	Inflammatory Bowel Diseases S Ghosh Gut 2004; 53: 1880. [Extract] [Full text] [PDF] [Request Permissions]