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February 2004 (Volume 53, Number 2). [Index by author]

	(Cover illustration)	Leading articles Digest GI snapshot Commentaries Oesophagus Stomach Gastric cancer Intestine Intestine inflammation Intestine cancer Intestine microbiology Inflammatory bowel disease Colon cancer Recent advances in clinical science Debate H pylori eradication and Gord JournalScan Letters Corrections

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Leading articles

Endothelin and vascular function in liver disease
K Moore
Gut 2004; 53: 159-161. doi:10.1136/gut.2003.024703 [Abstract] [Full text] [PDF] [Request Permissions]

Digest

Digest
Robin Spiller
Gut 2004; 53: 159. [Extract] [Full text] [PDF] [Request Permissions]

GI snapshot

Cerebral venous thrombosis in acute inflammatory bowel disease
G Singh, S Sarkar, K Manoj, C Shorrock, and P Isaacs
Gut 2004; 53: 161. doi:10.1136/gut.2003.027730 [Extract] [Full text] [PDF] [Request Permissions]

GI SNAPSHOT
Gut 2004; 53: 206. doi:10.1136/gut.2003.27730A [Extract] [Full text] [PDF] [Request Permissions]

Commentaries

Are we underestimating acid reflux?
S J Spechler
Gut 2004; 53: 162-163. doi:10.1136/gut.2003.025205 [Extract] [Full text] [PDF] [Request Permissions]

A snapshot of colonoscopy practice in England: stimulus for improvement
K Palmer and A I Morris
Gut 2004; 53: 163-165. doi:10.1136/gut.2003.022053 [Extract] [Full text] [PDF] [Request Permissions]

Surveillance colonoscopy in ulcerative colitis: magnifying chromoendoscopy in the spotlight
R Kiesslich and M F Neurath
Gut 2004; 53: 165-167. doi:10.1136/gut.2003.026351 [Extract] [Full text] [PDF] [Request Permissions]

Oesophagus

Studies of acid exposure immediately above the gastro-oesophageal squamocolumnar junction: evidence of short segment reflux
J Fletcher, A Wirz, E Henry, and K E L McColl
Gut 2004; 53: 168-173. doi:10.1136/gut.2003.022160 [Abstract] [Full text] [PDF] [Request Permissions]

Effect of Helicobacter pylori eradication on treatment of gastro-oesophageal reflux disease: a double blind, placebo controlled, randomised trial
J C Y Wu, F K L Chan, J Y L Ching, W-K Leung, Y Hui, R Leong, S C S Chung, and J J Y Sung
Gut 2004; 53: 174-179. doi:10.1136/gut.2003.012641 [Abstract] [Full text] [PDF] [Request Permissions]

Effect of childhood adversity on health related quality of life in patients with upper abdominal or chest pain
A-M Biggs, Q Aziz, B Tomenson, and F Creed
Gut 2004; 53: 180-186. doi:10.1136/gut.2003.020974 [Abstract] [Full text] [PDF] [Request Permissions]

Stomach

Helicobacter pylori infection modifies gastric and plasma ghrelin dynamics in Mongolian gerbils
H Suzuki, T Masaoka, H Hosoda, T Ota, Y Minegishi, S Nomura, K Kangawa, and H Ishii
Gut 2004; 53: 187-194. doi:10.1136/gut.2003.021568 [Abstract] [Full text] [PDF] [Request Permissions]

Gastric cancer

Chemoprevention of gastric cancer by celecoxib in rats
P J Hu, J Yu, Z R Zeng, W K Leung, H L Lin, B D Tang, A H C Bai, and J J Y Sung
Gut 2004; 53: 195-200. doi:10.1136/gut.2003.021477 [Abstract] [Full text] [PDF] [Request Permissions]

Intestine

Mislocalisation of hephaestin, a multicopper ferroxidase involved in basolateral intestinal iron transport, in the sex linked anaemia mouse
Y M Kuo, T Su, H Chen, Z Attieh, B A Syed, A T McKie, G J Anderson, J Gitschier, and C D Vulpe
Gut 2004; 53: 201-206. doi:10.1136/gut.2003.019026 [Abstract] [Full text] [PDF] [Request Permissions]

Intestine inflammation

The role of platelet activating factor in a neonatal piglet model of necrotising enterocolitis
A K Ewer, W Al-Salti, A M Coney, J M Marshall, P Ramani, and I W Booth
Gut 2004; 53: 207-213. doi:10.1136/gut.2003.024521 [Abstract] [Full text] [PDF] [Request Permissions]

Nitric oxide inhibitable isoforms of adenylate cyclase mediate epithelial secretory dysfunction following exposure to ionising radiation
S L Freeman and W K MacNaughton
Gut 2004; 53: 214-221. doi:10.1136/gut.2003.023895 [Abstract] [Full text] [PDF] [Request Permissions]

Proinflammatory cytokines increase glial fibrillary acidic protein expression in enteric glia
G B T von Boyen, M Steinkamp, M Reinshagen, K-H Schäfer, G Adler, and J Kirsch
Gut 2004; 53: 222-228. doi:10.1136/gut.2003.012625 [Abstract] [Full text] [PDF] [Request Permissions]

Evidence for the presence of functional protease activated receptor 4 (PAR₄) in the rat colon
F Mulè, R Pizzuti, A Capparelli, and N Vergnolle
Gut 2004; 53: 229-234. doi:10.1136/gut.2003.021899 [Abstract] [Full text] [PDF] [Request Permissions]

Intestine cancer

Molecular targets for tumour progression in gastrointestinal stromal tumours
N Koon, R Schneider-Stock, M Sarlomo-Rikala, J Lasota, M Smolkin, G Petroni, A Zaika, C Boltze, F Meyer, L Andersson, S Knuutila, M Miettinen, and W El-Rifai
Gut 2004; 53: 235-240. doi:10.1136/gut.2003.021238 [Abstract] [Full text] [PDF] [Request Permissions]

Intestine microbiology

Randomised clinical trial of synbiotic therapy in elective surgical patients
A D G Anderson, C E McNaught, P K Jain, and J MacFie
Gut 2004; 53: 241-245. doi:10.1136/gut.2003.024620 [Abstract] [Full text] [PDF] [Request Permissions]

Inflammatory bowel disease

Antibiotic use and the development of Crohn’s disease
T Card, R F A Logan, L C Rodrigues, and J G Wheeler
Gut 2004; 53: 246-250. doi:10.1136/gut.2003.025239 [Abstract] [Full text] [PDF] [Request Permissions]

Hip fractures in patients with inflammatory bowel disease and their relationship to corticosteroid use: a population based cohort study
T Card, J West, R Hubbard, and R F A Logan
Gut 2004; 53: 251-255. doi:10.1136/gut.2003.026799 [Abstract] [Full text] [PDF] [Request Permissions]

Pancolonic indigo carmine dye spraying for the detection of dysplasia in ulcerative colitis
M D Rutter, B P Saunders, G Schofield, A Forbes, A B Price, and I C Talbot
Gut 2004; 53: 256-260. doi:10.1136/gut.2003.016386 [Abstract] [Full text] [PDF] [Request Permissions]

Colon cancer

Sporadic duodenal adenoma is associated with colorectal neoplasia
M A Murray, M J Zimmerman, and H C Ee
Gut 2004; 53: 261-265. doi:10.1136/gut.2003.025320 [Abstract] [Full text] [PDF] [Request Permissions]

Familial adenomatous polyposis patients without an identified APC germline mutation have a severe phenotype
M L Bisgaard, R Ripa, A L Knudsen, and S Bülow
Gut 2004; 53: 266-270. doi:10.1136/gut.2003.019042 [Abstract] [Full text] [PDF] [Request Permissions]

Analysis of candidate modifier loci for the severity of colonic familial adenomatous polyposis, with evidence for the importance of the N-acetyl transferases
M D Crabtree, C Fletcher, M Churchman, S V Hodgson, K Neale, R K S Phillips, and I P M Tomlinson
Gut 2004; 53: 271-276. doi:10.1136/gut.2003.015586 [Abstract] [Full text] [PDF] [Request Permissions]

A prospective study of colonoscopy practice in the UK today: are we adequately prepared for national colorectal cancer screening tomorrow?
C J A Bowles, R Leicester, C Romaya, E Swarbrick, C B Williams, and O Epstein
Gut 2004; 53: 277-283. doi:10.1136/gut.2003.016436 [Abstract] [Full text] [PDF] [Request Permissions]

Efficacy of high magnification chromoscopic colonoscopy for the diagnosis of neoplasia in flat and depressed lesions of the colorectum: a prospective analysis
D P Hurlstone, S S Cross, I Adam, A J Shorthouse, S Brown, D S Sanders, and A J Lobo
Gut 2004; 53: 284-290. doi:10.1136/gut.2003.027623 [Abstract] [Full text] [PDF] [Request Permissions]

Accuracy of reporting of family history of colorectal cancer
R J Mitchell, D Brewster, H Campbell, M E M Porteous, A H Wyllie, C C Bird, and M G Dunlop
Gut 2004; 53: 291-295. doi:10.1136/gut.2003.027896 [Abstract] [Full text] [PDF] [Request Permissions]

Recent advances in clinical science

Management of infectious diarrhoea
A C Casburn-Jones and M J G Farthing
Gut 2004; 53: 296-305. doi:10.1136/gut.2003.022103 [Extract] [Full text] [PDF] [Request Permissions]

Debate

Early surgical intervention in ulcerative colitis
R R Cima and J H Pemberton
Gut 2004; 53: 306-307. doi:10.1136/gut.2003.001719 [Extract] [Full text] [PDF] [Request Permissions]

Early surgical intervention in ulcerative colitis
M A Kamm
Gut 2004; 53: 308-309. doi:10.1136/gut.2003.001727 [Extract] [Full text] [PDF] [Request Permissions]

H pylori eradication and Gord

Effect of Helicobacter pylori eradication on the treatment of gastro-oesophageal reflux disease
J E Richter
Gut 2004; 53: 310-311. doi:10.1136/gut.2003.019844 [Abstract] [Full text] [PDF] [Request Permissions]

Helicobacter pylori eradication does not exacerbate gastro-oesophageal reflux disease
P Malfertheiner
Gut 2004; 53: 312-313. doi:10.1136/gut.2003.019836 [Abstract] [Full text] [PDF] [Request Permissions]

JournalScan

JournalScan
Gut 2004; 53: 314. [Extract] [Full text] [PDF] [Request Permissions]

Letters

Ghrelin and Helicobacter pylori • Authors’ reply
C D R Murray, A V Emmanuel, C U Nwokolo, and H Randeva
Gut 2004; 53: 315. [Extract] [Full text] [PDF] [Request Permissions]

Helicobacter pylori, ghrelin, and obesity • Author’s reply
R C Macadam, V Borse, I Dodo, S G Pollard, C U Nwokolo, and H Randeva
Gut 2004; 53: 315-316. [Extract] [Full text] [PDF] [Request Permissions]

Corrections

CORRECTION
Gut 2004; 53: 316. [Extract] [Full text] [PDF] [Request Permissions]

Cover

Effect of cytokines on enteric glia (from the paper by von Boyen et al, pp 222-8).

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	Endothelin and vascular function in liver disease K Moore Gut 2004; 53: 159-161. doi:10.1136/gut.2003.024703 [Abstract] [Full text] [PDF] [Request Permissions]

	Digest Robin Spiller Gut 2004; 53: 159. [Extract] [Full text] [PDF] [Request Permissions]

	Cerebral venous thrombosis in acute inflammatory bowel disease G Singh, S Sarkar, K Manoj, C Shorrock, and P Isaacs Gut 2004; 53: 161. doi:10.1136/gut.2003.027730 [Extract] [Full text] [PDF] [Request Permissions]

	GI SNAPSHOT Gut 2004; 53: 206. doi:10.1136/gut.2003.27730A [Extract] [Full text] [PDF] [Request Permissions]

	Are we underestimating acid reflux? S J Spechler Gut 2004; 53: 162-163. doi:10.1136/gut.2003.025205 [Extract] [Full text] [PDF] [Request Permissions]

	A snapshot of colonoscopy practice in England: stimulus for improvement K Palmer and A I Morris Gut 2004; 53: 163-165. doi:10.1136/gut.2003.022053 [Extract] [Full text] [PDF] [Request Permissions]

	Surveillance colonoscopy in ulcerative colitis: magnifying chromoendoscopy in the spotlight R Kiesslich and M F Neurath Gut 2004; 53: 165-167. doi:10.1136/gut.2003.026351 [Extract] [Full text] [PDF] [Request Permissions]

	Studies of acid exposure immediately above the gastro-oesophageal squamocolumnar junction: evidence of short segment reflux J Fletcher, A Wirz, E Henry, and K E L McColl Gut 2004; 53: 168-173. doi:10.1136/gut.2003.022160 [Abstract] [Full text] [PDF] [Request Permissions]

	*Effect of Helicobacter pylori* eradication on treatment of gastro-oesophageal reflux disease: a double blind, placebo controlled, randomised trial** J C Y Wu, F K L Chan, J Y L Ching, W-K Leung, Y Hui, R Leong, S C S Chung, and J J Y Sung Gut 2004; 53: 174-179. doi:10.1136/gut.2003.012641 [Abstract] [Full text] [PDF] [Request Permissions]

	Effect of childhood adversity on health related quality of life in patients with upper abdominal or chest pain A-M Biggs, Q Aziz, B Tomenson, and F Creed Gut 2004; 53: 180-186. doi:10.1136/gut.2003.020974 [Abstract] [Full text] [PDF] [Request Permissions]

	Helicobacter pylori infection modifies gastric and plasma ghrelin dynamics in Mongolian gerbils H Suzuki, T Masaoka, H Hosoda, T Ota, Y Minegishi, S Nomura, K Kangawa, and H Ishii Gut 2004; 53: 187-194. doi:10.1136/gut.2003.021568 [Abstract] [Full text] [PDF] [Request Permissions]

	Chemoprevention of gastric cancer by celecoxib in rats P J Hu, J Yu, Z R Zeng, W K Leung, H L Lin, B D Tang, A H C Bai, and J J Y Sung Gut 2004; 53: 195-200. doi:10.1136/gut.2003.021477 [Abstract] [Full text] [PDF] [Request Permissions]

	Mislocalisation of hephaestin, a multicopper ferroxidase involved in basolateral intestinal iron transport, in the sex linked anaemia mouse Y M Kuo, T Su, H Chen, Z Attieh, B A Syed, A T McKie, G J Anderson, J Gitschier, and C D Vulpe Gut 2004; 53: 201-206. doi:10.1136/gut.2003.019026 [Abstract] [Full text] [PDF] [Request Permissions]

	The role of platelet activating factor in a neonatal piglet model of necrotising enterocolitis A K Ewer, W Al-Salti, A M Coney, J M Marshall, P Ramani, and I W Booth Gut 2004; 53: 207-213. doi:10.1136/gut.2003.024521 [Abstract] [Full text] [PDF] [Request Permissions]

	Nitric oxide inhibitable isoforms of adenylate cyclase mediate epithelial secretory dysfunction following exposure to ionising radiation S L Freeman and W K MacNaughton Gut 2004; 53: 214-221. doi:10.1136/gut.2003.023895 [Abstract] [Full text] [PDF] [Request Permissions]

	Proinflammatory cytokines increase glial fibrillary acidic protein expression in enteric glia G B T von Boyen, M Steinkamp, M Reinshagen, K-H Schäfer, G Adler, and J Kirsch Gut 2004; 53: 222-228. doi:10.1136/gut.2003.012625 [Abstract] [Full text] [PDF] [Request Permissions]

	Evidence for the presence of functional protease activated receptor 4 (PAR₄) in the rat colon F Mulè, R Pizzuti, A Capparelli, and N Vergnolle Gut 2004; 53: 229-234. doi:10.1136/gut.2003.021899 [Abstract] [Full text] [PDF] [Request Permissions]

	Molecular targets for tumour progression in gastrointestinal stromal tumours N Koon, R Schneider-Stock, M Sarlomo-Rikala, J Lasota, M Smolkin, G Petroni, A Zaika, C Boltze, F Meyer, L Andersson, S Knuutila, M Miettinen, and W El-Rifai Gut 2004; 53: 235-240. doi:10.1136/gut.2003.021238 [Abstract] [Full text] [PDF] [Request Permissions]

	Randomised clinical trial of synbiotic therapy in elective surgical patients A D G Anderson, C E McNaught, P K Jain, and J MacFie Gut 2004; 53: 241-245. doi:10.1136/gut.2003.024620 [Abstract] [Full text] [PDF] [Request Permissions]

	Antibiotic use and the development of Crohn’s disease T Card, R F A Logan, L C Rodrigues, and J G Wheeler Gut 2004; 53: 246-250. doi:10.1136/gut.2003.025239 [Abstract] [Full text] [PDF] [Request Permissions]

	Hip fractures in patients with inflammatory bowel disease and their relationship to corticosteroid use: a population based cohort study T Card, J West, R Hubbard, and R F A Logan Gut 2004; 53: 251-255. doi:10.1136/gut.2003.026799 [Abstract] [Full text] [PDF] [Request Permissions]

	Pancolonic indigo carmine dye spraying for the detection of dysplasia in ulcerative colitis M D Rutter, B P Saunders, G Schofield, A Forbes, A B Price, and I C Talbot Gut 2004; 53: 256-260. doi:10.1136/gut.2003.016386 [Abstract] [Full text] [PDF] [Request Permissions]

	Sporadic duodenal adenoma is associated with colorectal neoplasia M A Murray, M J Zimmerman, and H C Ee Gut 2004; 53: 261-265. doi:10.1136/gut.2003.025320 [Abstract] [Full text] [PDF] [Request Permissions]

	*Familial adenomatous polyposis patients without an identified APC* germline mutation have a severe phenotype** M L Bisgaard, R Ripa, A L Knudsen, and S Bülow Gut 2004; 53: 266-270. doi:10.1136/gut.2003.019042 [Abstract] [Full text] [PDF] [Request Permissions]

	Analysis of candidate modifier loci for the severity of colonic familial adenomatous polyposis, with evidence for the importance of the N-acetyl transferases M D Crabtree, C Fletcher, M Churchman, S V Hodgson, K Neale, R K S Phillips, and I P M Tomlinson Gut 2004; 53: 271-276. doi:10.1136/gut.2003.015586 [Abstract] [Full text] [PDF] [Request Permissions]

	A prospective study of colonoscopy practice in the UK today: are we adequately prepared for national colorectal cancer screening tomorrow? C J A Bowles, R Leicester, C Romaya, E Swarbrick, C B Williams, and O Epstein Gut 2004; 53: 277-283. doi:10.1136/gut.2003.016436 [Abstract] [Full text] [PDF] [Request Permissions]

	Efficacy of high magnification chromoscopic colonoscopy for the diagnosis of neoplasia in flat and depressed lesions of the colorectum: a prospective analysis D P Hurlstone, S S Cross, I Adam, A J Shorthouse, S Brown, D S Sanders, and A J Lobo Gut 2004; 53: 284-290. doi:10.1136/gut.2003.027623 [Abstract] [Full text] [PDF] [Request Permissions]

	Accuracy of reporting of family history of colorectal cancer R J Mitchell, D Brewster, H Campbell, M E M Porteous, A H Wyllie, C C Bird, and M G Dunlop Gut 2004; 53: 291-295. doi:10.1136/gut.2003.027896 [Abstract] [Full text] [PDF] [Request Permissions]

	Management of infectious diarrhoea A C Casburn-Jones and M J G Farthing Gut 2004; 53: 296-305. doi:10.1136/gut.2003.022103 [Extract] [Full text] [PDF] [Request Permissions]

	Early surgical intervention in ulcerative colitis R R Cima and J H Pemberton Gut 2004; 53: 306-307. doi:10.1136/gut.2003.001719 [Extract] [Full text] [PDF] [Request Permissions]

	Early surgical intervention in ulcerative colitis M A Kamm Gut 2004; 53: 308-309. doi:10.1136/gut.2003.001727 [Extract] [Full text] [PDF] [Request Permissions]

	*Effect of Helicobacter pylori* eradication on the treatment of gastro-oesophageal reflux disease** J E Richter Gut 2004; 53: 310-311. doi:10.1136/gut.2003.019844 [Abstract] [Full text] [PDF] [Request Permissions]

	Helicobacter pylori eradication does not exacerbate gastro-oesophageal reflux disease P Malfertheiner Gut 2004; 53: 312-313. doi:10.1136/gut.2003.019836 [Abstract] [Full text] [PDF] [Request Permissions]

	JournalScan Gut 2004; 53: 314. [Extract] [Full text] [PDF] [Request Permissions]

	*Ghrelin and Helicobacter pylori* • Authors’ reply** C D R Murray, A V Emmanuel, C U Nwokolo, and H Randeva Gut 2004; 53: 315. [Extract] [Full text] [PDF] [Request Permissions]

	Helicobacter pylori, ghrelin, and obesity • Author’s reply R C Macadam, V Borse, I Dodo, S G Pollard, C U Nwokolo, and H Randeva Gut 2004; 53: 315-316. [Extract] [Full text] [PDF] [Request Permissions]

	CORRECTION Gut 2004; 53: 316. [Extract] [Full text] [PDF] [Request Permissions]