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May 2004 (Volume 53, Number 5). [Index by author]

	(Cover illustration)	Leading articles Digest Commentaries Oesophagus Small intestine Irritable bowel syndrome Gastrointestinal infection Inflammation Inflammatory bowel disease Colon Pancreas Biliary disease Liver Case reports Recent advances in clinical practice JournalScan Letters Corrections

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Leading articles

Hepcidin and its role in iron absorption
K J Robson
Gut 2004; 53: 617-619. doi:10.1136/gut.2003.027631 [Abstract] [Full text] [PDF] [Request Permissions]

Digest

Digest
Robin Spiller
Gut 2004; 53: 617. [Extract] [Full text] [PDF] [Request Permissions]

Commentaries

Probiotics in inflammatory bowel disease: is it all gut flora modulation?
S Ghosh, D van Heel, and R J Playford
Gut 2004; 53: 620-622. doi:10.1136/gut.2003.034249 [Extract] [Full text] [PDF] [Request Permissions]

Fistulising Crohn’s disease: MMPs gone awry
D Schuppan and T Freitag
Gut 2004; 53: 622-624. doi:10.1136/gut.2003.034207 [Extract] [Full text] [PDF] [Request Permissions]

Hepcidin: what every gastroenterologist should know
A P Walker, J Partridge, S K Srai, and J S Dooley
Gut 2004; 53: 624-627. doi:10.1136/gut.2003.030304 [Extract] [Full text] [PDF] [Request Permissions]

Bringing science to the art of diagnosis
P Moayyedi
Gut 2004; 53: 627-628. doi:10.1136/gut.2003.032219 [Extract] [Full text] [PDF] [Request Permissions]

Oesophagus

Pneumatic dilation for achalasia: late results of a prospective follow up investigation
V F Eckardt, I Gockel, and G Bernhard
Gut 2004; 53: 629-633. doi:10.1136/gut.2003.029298 [Abstract] [Full text] [PDF] [Request Permissions]

Accuracy of staging in early oesophageal cancer using high resolution endoscopy and high resolution endosonography: a comparative, prospective, and blinded trial
A May, E Günter, F Roth, L Gossner, M Stolte, M Vieth, and C Ell
Gut 2004; 53: 634-640. doi:10.1136/gut.2003.029421 [Abstract] [Full text] [PDF] [Request Permissions]

Small intestine

In vivo targeting of intestinal and extraintestinal transglutaminase 2 by coeliac autoantibodies
I R Korponay-Szabó, T Halttunen, Z Szalai, K Laurila, R Király, J B Kovács, L Fésüs, and M Mäki
Gut 2004; 53: 641-648. doi:10.1136/gut.2003.024836 [Abstract] [Full text] [PDF] [Request Permissions]

Oats to children with newly diagnosed coeliac disease: a randomised double blind study
L Högberg, P Laurin, K Fälth-Magnusson, C Grant, E Grodzinsky, G Jansson, H Ascher, L Browaldh, J-Å Hammersjö, E Lindberg, U Myrdal, and L Stenhammar
Gut 2004; 53: 649-654. doi:10.1136/gut.2003.026948 [Abstract] [Full text] [PDF] [Request Permissions]

Changes in the expression of intestinal iron transport and hepatic regulatory molecules explain the enhanced iron absorption associated with pregnancy in the rat
K N Millard, D M Frazer, S J Wilkins, and G J Anderson
Gut 2004; 53: 655-660. doi:10.1136/gut.2003.031153 [Abstract] [Full text] [PDF] [Request Permissions]

Sites of symptomatic gas retention during intestinal lipid perfusion in healthy subjects
A C Hernando-Harder, J Serra, F Azpiroz, and J-R Malagelada
Gut 2004; 53: 661-665. doi:10.1136/gut.2003.026385 [Abstract] [Full text] [PDF] [Request Permissions]

Irritable bowel syndrome

Diagnostic yield of alarm features in irritable bowel syndrome and functional dyspepsia
J Hammer, G D Eslick, S C Howell, E Altiparmak, and N J Talley
Gut 2004; 53: 666-672. doi:10.1136/gut.2003.021857 [Abstract] [Full text] [PDF] [Request Permissions]

Gastrointestinal infection

Clostridium difficile associated diarrhoea in hospitalised patients: onset in the community and hospital and role of flexible sigmoidoscopy
S S Johal, J Hammond, K Solomon, P D James, and Y R Mahida
Gut 2004; 53: 673-677. doi:10.1136/gut.2003.028803 [Abstract] [Full text] [PDF] [Request Permissions]

Inflammation

Colonic epithelial cell mediated suppression of CD4 T cell activation
S M Cruickshank, L D McVay, D C Baumgart, P J Felsburg, and S R Carding
Gut 2004; 53: 678-684. doi:10.1136/gut.2003.029967 [Abstract] [Full text] [PDF] [Request Permissions]

Inflammatory bowel disease

Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease
S J Ott, M Musfeldt, D F Wenderoth, J Hampe, O Brant, U R Fölsch, K N Timmis, and S Schreiber
Gut 2004; 53: 685-693. doi:10.1136/gut.2003.025403 [Abstract] [Full text] [PDF] [Request Permissions]

Is the mucosal route of administration essential for probiotic function? Subcutaneous administration is associated with attenuation of murine colitis and arthritis
B Sheil, J McCarthy, L O’Mahony, M W Bennett, P Ryan, J J Fitzgibbon, B Kiely, J K Collins, and F Shanahan
Gut 2004; 53: 694-700. doi:10.1136/gut.2003.027789 [Abstract] [Full text] [PDF] [Request Permissions]

Expression and localisation of matrix metalloproteinases and their natural inhibitors in fistulae of patients with Crohn’s disease
T Kirkegaard, A Hansen, E Bruun, and J Brynskov
Gut 2004; 53: 701-709. doi:10.1136/gut.2003.017442 [Abstract] [Full text] [PDF] [Request Permissions]

Development of colonic neoplasia in p53 deficient mice with experimental colitis induced by dextran sulphate sodium
S Fujii, T Fujimori, H Kawamata, J Takeda, K Kitajima, F Omotehara, T Kaihara, T Kusaka, K Ichikawa, Y Ohkura, Y Ono, J Imura, S Yamaoka, C Sakamoto, Y Ueda, and T Chiba
Gut 2004; 53: 710-716. doi:10.1136/gut.2003.028779 [Abstract] [Full text] [PDF] [Request Permissions]

Colon

Colorectal visceral perception in diverticular disease
C H M Clemens, M Samsom, J Roelofs, G P van Berge Henegouwen, and A J P M Smout
Gut 2004; 53: 717-722. doi:10.1136/gut.2003.018093 [Abstract] [Full text] [PDF] [Request Permissions]

Pancreas

Absence of PRSS1 mutations and association of SPINK1 trypsin inhibitor mutations in hereditary and non-hereditary chronic pancreatitis
G R Chandak, M M Idris, D N Reddy, K R Mani, S Bhaskar, G V Rao, and L Singh
Gut 2004; 53: 723-728. doi:10.1136/gut.2003.026526 [Abstract] [Full text] [PDF] [Request Permissions]

Biliary disease

A prospective randomised study of "covered" versus "uncovered" diamond stents for the management of distal malignant biliary obstruction
H Isayama, Y Komatsu, T Tsujino, N Sasahira, K Hirano, N Toda, Y Nakai, N Yamamoto, M Tada, H Yoshida, Y Shiratori, T Kawabe, and M Omata
Gut 2004; 53: 729-734. doi:10.1136/gut.2003.018945 [Abstract] [Full text] [PDF] [Request Permissions]

Liver

Pro-hepcidin: expression and cell specific localisation in the liver and its regulation in hereditary haemochromatosis, chronic renal insufficiency, and renal anaemia
H Kulaksiz, S G Gehrke, A Janetzko, D Rost, T Bruckner, B Kallinowski, and W Stremmel
Gut 2004; 53: 735-743. doi:10.1136/gut.2003.022863 [Abstract] [Full text] [PDF] [Request Permissions]

Natural history of compensated viral cirrhosis: a prospective study on the incidence and hierarchy of major complications
L Benvegnù, M Gios, S Boccato, and A Alberti
Gut 2004; 53: 744-749. doi:10.1136/gut.2003.020263 [Abstract] [Full text] [PDF] [Request Permissions]

Long term prognosis of fatty liver: risk of chronic liver disease and death
S Dam-Larsen, M Franzmann, I B Andersen, P Christoffersen, L B Jensen, T I A Sørensen, U Becker, and F Bendtsen
Gut 2004; 53: 750-755. doi:10.1136/gut.2003.019984 [Abstract] [Full text] [PDF] [Request Permissions]

Case reports

Iron chelation therapy in aceruloplasminaemia: study of a patient with a novel missense mutation
R Mariani, C Arosio, S Pelucchi, M Grisoli, A Piga, P Trombini, and A Piperno
Gut 2004; 53: 756-758. doi:10.1136/gut.2003.030429 [Abstract] [Full text] [PDF] [Request Permissions]

Recent advances in clinical practice

Developments in liver transplantation
J Neuberger
Gut 2004; 53: 759-768. doi:10.1136/gut.2003.024927 [Extract] [Full text] [PDF] [Request Permissions]

JournalScan

JournalScan
Gut 2004; 53: 769. [Extract] [Full text] [PDF] [Request Permissions]

Letters

Investigation of chronic diarrhoea • Authors’ reply
R C G Pollok, P Thomas, and A Forbes
Gut 2004; 53: 770. [Extract] [Full text] [PDF] [Request Permissions]

Interstitial pneumonia associated with autoimmune pancreatitis • Author’s reply
T Taniguchi, M Ko, S Seko, O Nishida, F Inoue, H Kobayashi, T Saiga, M Okamoto, T Fukuse, T Kamisawa, N Funata, and A Okamoto
Gut 2004; 53: 770-771. [Extract] [Full text] [PDF] [Request Permissions]

The diagnostic dilemmas in discrimination between pancreatic carcinoma and chronic pancreatitis
P Ruszniewski, D Malka, P Hammel, F Maire, P Rufat, I Madeira, F Pessione, and P Lévy
Gut 2004; 53: 771. [Extract] [Full text] [PDF] [Request Permissions]

In search of the correct strategy for preventing the spread of HCV infection
M Montella, A Crispo, and J Wynn-Bellezza
Gut 2004; 53: 771-772. [Extract] [Full text] [PDF] [Request Permissions]

Cross reactivity due to positive canrenone interference
R G Romanelli and P Gentilini
Gut 2004; 53: 772-773. [Extract] [Full text] [PDF] [Request Permissions]

Responses to endothelin-1 in patients with advanced cirrhosis before and after liver transplantation
P W Angus, R B Vaughan, and J P F Chin-Dusting
Gut 2004; 53: 773. [Extract] [Full text] [PDF] [Request Permissions]

Cluster’s last stand
S C Howell, G D Eslick, and N J Talley
Gut 2004; 53: 773-774. [Extract] [Full text] [PDF] [Request Permissions]

Small bowel carcinoma and coeliac disease
P H R Green and S D Rampertab
Gut 2004; 53: 774. [Extract] [Full text] [PDF] [Request Permissions]

Corrections

RETRACTION
Gut 2004; 53: 774. [Extract] [Full text] [PDF] [Request Permissions]

Cover

Expression and regulation of pro-hepcidin (from the paper by Kulaksiz et al, pp 735-43).

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	Hepcidin and its role in iron absorption K J Robson Gut 2004; 53: 617-619. doi:10.1136/gut.2003.027631 [Abstract] [Full text] [PDF] [Request Permissions]

	Digest Robin Spiller Gut 2004; 53: 617. [Extract] [Full text] [PDF] [Request Permissions]

	Probiotics in inflammatory bowel disease: is it all gut flora modulation? S Ghosh, D van Heel, and R J Playford Gut 2004; 53: 620-622. doi:10.1136/gut.2003.034249 [Extract] [Full text] [PDF] [Request Permissions]

	Fistulising Crohn’s disease: MMPs gone awry D Schuppan and T Freitag Gut 2004; 53: 622-624. doi:10.1136/gut.2003.034207 [Extract] [Full text] [PDF] [Request Permissions]

	Hepcidin: what every gastroenterologist should know A P Walker, J Partridge, S K Srai, and J S Dooley Gut 2004; 53: 624-627. doi:10.1136/gut.2003.030304 [Extract] [Full text] [PDF] [Request Permissions]

	Bringing science to the art of diagnosis P Moayyedi Gut 2004; 53: 627-628. doi:10.1136/gut.2003.032219 [Extract] [Full text] [PDF] [Request Permissions]

	Pneumatic dilation for achalasia: late results of a prospective follow up investigation V F Eckardt, I Gockel, and G Bernhard Gut 2004; 53: 629-633. doi:10.1136/gut.2003.029298 [Abstract] [Full text] [PDF] [Request Permissions]

	Accuracy of staging in early oesophageal cancer using high resolution endoscopy and high resolution endosonography: a comparative, prospective, and blinded trial A May, E Günter, F Roth, L Gossner, M Stolte, M Vieth, and C Ell Gut 2004; 53: 634-640. doi:10.1136/gut.2003.029421 [Abstract] [Full text] [PDF] [Request Permissions]

	In vivo targeting of intestinal and extraintestinal transglutaminase 2 by coeliac autoantibodies I R Korponay-Szabó, T Halttunen, Z Szalai, K Laurila, R Király, J B Kovács, L Fésüs, and M Mäki Gut 2004; 53: 641-648. doi:10.1136/gut.2003.024836 [Abstract] [Full text] [PDF] [Request Permissions]

	Oats to children with newly diagnosed coeliac disease: a randomised double blind study L Högberg, P Laurin, K Fälth-Magnusson, C Grant, E Grodzinsky, G Jansson, H Ascher, L Browaldh, J-Å Hammersjö, E Lindberg, U Myrdal, and L Stenhammar Gut 2004; 53: 649-654. doi:10.1136/gut.2003.026948 [Abstract] [Full text] [PDF] [Request Permissions]

	Changes in the expression of intestinal iron transport and hepatic regulatory molecules explain the enhanced iron absorption associated with pregnancy in the rat K N Millard, D M Frazer, S J Wilkins, and G J Anderson Gut 2004; 53: 655-660. doi:10.1136/gut.2003.031153 [Abstract] [Full text] [PDF] [Request Permissions]

	Sites of symptomatic gas retention during intestinal lipid perfusion in healthy subjects A C Hernando-Harder, J Serra, F Azpiroz, and J-R Malagelada Gut 2004; 53: 661-665. doi:10.1136/gut.2003.026385 [Abstract] [Full text] [PDF] [Request Permissions]

	Diagnostic yield of alarm features in irritable bowel syndrome and functional dyspepsia J Hammer, G D Eslick, S C Howell, E Altiparmak, and N J Talley Gut 2004; 53: 666-672. doi:10.1136/gut.2003.021857 [Abstract] [Full text] [PDF] [Request Permissions]

	Clostridium difficile associated diarrhoea in hospitalised patients: onset in the community and hospital and role of flexible sigmoidoscopy S S Johal, J Hammond, K Solomon, P D James, and Y R Mahida Gut 2004; 53: 673-677. doi:10.1136/gut.2003.028803 [Abstract] [Full text] [PDF] [Request Permissions]

	Colonic epithelial cell mediated suppression of CD4 T cell activation S M Cruickshank, L D McVay, D C Baumgart, P J Felsburg, and S R Carding Gut 2004; 53: 678-684. doi:10.1136/gut.2003.029967 [Abstract] [Full text] [PDF] [Request Permissions]

	Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease S J Ott, M Musfeldt, D F Wenderoth, J Hampe, O Brant, U R Fölsch, K N Timmis, and S Schreiber Gut 2004; 53: 685-693. doi:10.1136/gut.2003.025403 [Abstract] [Full text] [PDF] [Request Permissions]

	Is the mucosal route of administration essential for probiotic function? Subcutaneous administration is associated with attenuation of murine colitis and arthritis B Sheil, J McCarthy, L O’Mahony, M W Bennett, P Ryan, J J Fitzgibbon, B Kiely, J K Collins, and F Shanahan Gut 2004; 53: 694-700. doi:10.1136/gut.2003.027789 [Abstract] [Full text] [PDF] [Request Permissions]

	Expression and localisation of matrix metalloproteinases and their natural inhibitors in fistulae of patients with Crohn’s disease T Kirkegaard, A Hansen, E Bruun, and J Brynskov Gut 2004; 53: 701-709. doi:10.1136/gut.2003.017442 [Abstract] [Full text] [PDF] [Request Permissions]

	Development of colonic neoplasia in p53 deficient mice with experimental colitis induced by dextran sulphate sodium S Fujii, T Fujimori, H Kawamata, J Takeda, K Kitajima, F Omotehara, T Kaihara, T Kusaka, K Ichikawa, Y Ohkura, Y Ono, J Imura, S Yamaoka, C Sakamoto, Y Ueda, and T Chiba Gut 2004; 53: 710-716. doi:10.1136/gut.2003.028779 [Abstract] [Full text] [PDF] [Request Permissions]

	Colorectal visceral perception in diverticular disease C H M Clemens, M Samsom, J Roelofs, G P van Berge Henegouwen, and A J P M Smout Gut 2004; 53: 717-722. doi:10.1136/gut.2003.018093 [Abstract] [Full text] [PDF] [Request Permissions]

	Absence of PRSS1 mutations and association of SPINK1 trypsin inhibitor mutations in hereditary and non-hereditary chronic pancreatitis G R Chandak, M M Idris, D N Reddy, K R Mani, S Bhaskar, G V Rao, and L Singh Gut 2004; 53: 723-728. doi:10.1136/gut.2003.026526 [Abstract] [Full text] [PDF] [Request Permissions]

	A prospective randomised study of "covered" versus "uncovered" diamond stents for the management of distal malignant biliary obstruction H Isayama, Y Komatsu, T Tsujino, N Sasahira, K Hirano, N Toda, Y Nakai, N Yamamoto, M Tada, H Yoshida, Y Shiratori, T Kawabe, and M Omata Gut 2004; 53: 729-734. doi:10.1136/gut.2003.018945 [Abstract] [Full text] [PDF] [Request Permissions]

	Pro-hepcidin: expression and cell specific localisation in the liver and its regulation in hereditary haemochromatosis, chronic renal insufficiency, and renal anaemia H Kulaksiz, S G Gehrke, A Janetzko, D Rost, T Bruckner, B Kallinowski, and W Stremmel Gut 2004; 53: 735-743. doi:10.1136/gut.2003.022863 [Abstract] [Full text] [PDF] [Request Permissions]

	Natural history of compensated viral cirrhosis: a prospective study on the incidence and hierarchy of major complications L Benvegnù, M Gios, S Boccato, and A Alberti Gut 2004; 53: 744-749. doi:10.1136/gut.2003.020263 [Abstract] [Full text] [PDF] [Request Permissions]

	Long term prognosis of fatty liver: risk of chronic liver disease and death S Dam-Larsen, M Franzmann, I B Andersen, P Christoffersen, L B Jensen, T I A Sørensen, U Becker, and F Bendtsen Gut 2004; 53: 750-755. doi:10.1136/gut.2003.019984 [Abstract] [Full text] [PDF] [Request Permissions]

	Iron chelation therapy in aceruloplasminaemia: study of a patient with a novel missense mutation R Mariani, C Arosio, S Pelucchi, M Grisoli, A Piga, P Trombini, and A Piperno Gut 2004; 53: 756-758. doi:10.1136/gut.2003.030429 [Abstract] [Full text] [PDF] [Request Permissions]

	Developments in liver transplantation J Neuberger Gut 2004; 53: 759-768. doi:10.1136/gut.2003.024927 [Extract] [Full text] [PDF] [Request Permissions]

	JournalScan Gut 2004; 53: 769. [Extract] [Full text] [PDF] [Request Permissions]

	Investigation of chronic diarrhoea • Authors’ reply R C G Pollok, P Thomas, and A Forbes Gut 2004; 53: 770. [Extract] [Full text] [PDF] [Request Permissions]

	Interstitial pneumonia associated with autoimmune pancreatitis • Author’s reply T Taniguchi, M Ko, S Seko, O Nishida, F Inoue, H Kobayashi, T Saiga, M Okamoto, T Fukuse, T Kamisawa, N Funata, and A Okamoto Gut 2004; 53: 770-771. [Extract] [Full text] [PDF] [Request Permissions]

	The diagnostic dilemmas in discrimination between pancreatic carcinoma and chronic pancreatitis P Ruszniewski, D Malka, P Hammel, F Maire, P Rufat, I Madeira, F Pessione, and P Lévy Gut 2004; 53: 771. [Extract] [Full text] [PDF] [Request Permissions]

	In search of the correct strategy for preventing the spread of HCV infection M Montella, A Crispo, and J Wynn-Bellezza Gut 2004; 53: 771-772. [Extract] [Full text] [PDF] [Request Permissions]

	Cross reactivity due to positive canrenone interference R G Romanelli and P Gentilini Gut 2004; 53: 772-773. [Extract] [Full text] [PDF] [Request Permissions]

	Responses to endothelin-1 in patients with advanced cirrhosis before and after liver transplantation P W Angus, R B Vaughan, and J P F Chin-Dusting Gut 2004; 53: 773. [Extract] [Full text] [PDF] [Request Permissions]

	Cluster’s last stand S C Howell, G D Eslick, and N J Talley Gut 2004; 53: 773-774. [Extract] [Full text] [PDF] [Request Permissions]

	Small bowel carcinoma and coeliac disease P H R Green and S D Rampertab Gut 2004; 53: 774. [Extract] [Full text] [PDF] [Request Permissions]

	RETRACTION Gut 2004; 53: 774. [Extract] [Full text] [PDF] [Request Permissions]