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August 2004 (Volume 53, Number 8). [Index by author]

	(Cover illustration)	Leading articles Digest Miscellanea Commentaries Oesophagus Helicobacter pylori Coeliac disease Irritable bowel syndrome Small intestine Inflammatory bowel disease Colorectal cancer Pancreatic cancer Liver Reviews Recent advances in basic science Recent advances in clinical practice JournalScan Book reviews Corrections

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Leading articles

Effects of growth factors and receptor blockade on gastrointestinal cancer
R J Playford, H Wassan, and S Ghosh
Gut 2004; 53: 1059-1063. doi:10.1136/gut.2003.038620 [Abstract] [Full text] [PDF] [Request Permissions]

Digest

Digest
Robin Spiller
Gut 2004; 53: 1059. [Extract] [Full text] [PDF] [Request Permissions]

Miscellanea

A calcified caecal mass
A Hokama, T Makishi, R Tomiyama, F Kinjo, A Saito, S Yamashiro, I Kinjo, K Miyagi, Y Kuniyoshi, and K Koja
Gut 2004; 53: 1063. doi:10.1136/gut.2003.034009 [Extract] [Full text] [PDF] [Request Permissions]

EDITOR’S QUIZ: GI SNAPSHOT
Gut 2004; 53: 1081. [Extract] [Full text] [PDF] [Request Permissions]

A male with a pelvic mass
K T Kjossev, N N Vladov, and J E Losanoff
Gut 2004; 53: 1122. doi:10.1136/gut.2003.024638 [Extract] [Full text] [PDF] [Request Permissions]

EDITOR’S QUIZ: GI SNAPSHOT
Gut 2004; 53: 1144. [Extract] [Full text] [PDF] [Request Permissions]

An unusual case of abdominal pain
N Yazaki, K Shiiba, S Ishii, T Mizoi, K Miura, A Oyama, N Tanaka, Y Murata, and I Sasaki
Gut 2004; 53: 1150. doi:10.1136/gut.2003.023929 [Extract] [Full text] [PDF] [Request Permissions]

EDITOR’S QUIZ: GI SNAPSHOT
Gut 2004; 53: 1158. [Extract] [Full text] [PDF] [Request Permissions]

Commentaries

Oesophageal cancer and gastro-oesophageal reflux: what is the relationship?
J Lagergren
Gut 2004; 53: 1064-1065. doi:10.1136/gut.2003.038471 [Extract] [Full text] [PDF] [Request Permissions]

T helper cell polarisation in coeliac disease: any (T-)bet ?
M H Holtmann and M F Neurath
Gut 2004; 53: 1065-1067. doi:10.1136/gut.2003.038232 [Extract] [Full text] [PDF] [Request Permissions]

East meets West: infection, nerves, and mast cells in the irritable bowel syndrome
S M Collins and G Barbara
Gut 2004; 53: 1068-1069. doi:10.1136/gut.2004.038893 [Extract] [Full text] [PDF] [Request Permissions]

Oesophagus

Risk of oesophageal cancer in Barrett’s oesophagus and gastro-oesophageal reflux
M Solaymani-Dodaran, R F A Logan, J West, T Card, and C Coupland
Gut 2004; 53: 1070-1074. doi:10.1136/gut.2003.028076 [Abstract] [Full text] [PDF] [Request Permissions]

Helicobacter pylori

Effect of Th1 cytokines on acid secretion in pharmacologically characterised mouse gastric glands
I T Padol and R H Hunt
Gut 2004; 53: 1075-1081. doi:10.1136/gut.2003.026435 [Abstract] [Full text] [PDF] [Request Permissions]

Cytokine gene polymorphisms influence mucosal cytokine expression, gastric inflammation, and host specific colonisation during Helicobacter pylori infection
R Rad, A Dossumbekova, B Neu, R Lang, S Bauer, D Saur, M Gerhard, and C Prinz
Gut 2004; 53: 1082-1089. doi:10.1136/gut.2003.029736 [Abstract] [Full text] [PDF] [Request Permissions]

Coeliac disease

Regulation of the T helper cell type 1 transcription factor T-bet in coeliac disease mucosa
I Monteleone, G Monteleone, G Del Vecchio Blanco, P Vavassori, S Cucchiara, T T MacDonald, and F Pallone
Gut 2004; 53: 1090-1095. doi:10.1136/gut.2003.030551 [Abstract] [Full text] [PDF] [Request Permissions]

Irritable bowel syndrome

Bacillary dysentery as a causative factor of irritable bowel syndrome and its pathogenesis
L-H Wang, X-C Fang, and G-Z Pan
Gut 2004; 53: 1096-1101. doi:10.1136/gut.2003.021154 [Abstract] [Full text] [PDF] [Request Permissions]

Altered visceral perceptual and neuroendocrine response in patients with irritable bowel syndrome during mental stress
I Posserud, P Agerforz, R Ekman, E S Björnsson, H Abrahamsson, and M Simrén
Gut 2004; 53: 1102-1108. doi:10.1136/gut.2003.017962 [Abstract] [Full text] [PDF] [Request Permissions]

Small intestine

Chemical nociception in the jejunum induced by capsaicin
B Schmidt, J Hammer, P Holzer, and H F Hammer
Gut 2004; 53: 1109-1116. doi:10.1136/gut.2003.029793 [Abstract] [Full text] [PDF] [Request Permissions]

Inflammatory bowel disease

Anti-Saccharomyces cerevisiae antibody (ASCA) positivity is associated with increased risk for early surgery in Crohn’s disease
D G Forcione, M J Rosen, J B Kisiel, and B E Sands
Gut 2004; 53: 1117-1122. doi:10.1136/gut.2003.030734 [Abstract] [Full text] [PDF] [Request Permissions]

Clinical significance of azathioprine active metabolite concentrations in inflammatory bowel disease
S Wright, D S Sanders, A J Lobo, and L Lennard
Gut 2004; 53: 1123-1128. doi:10.1136/gut.2003.032896 [Abstract] [Full text] [PDF] [Request Permissions]

Measurement of vitamin D levels in inflammatory bowel disease patients reveals a subset of Crohn’s disease patients with elevated 1,25-dihydroxyvitamin D and low bone mineral density
M T Abreu, V Kantorovich, E A Vasiliauskas, U Gruntmanis, R Matuk, K Daigle, S Chen, D Zehnder, Y-C Lin, H Yang, M Hewison, and J S Adams
Gut 2004; 53: 1129-1136. doi:10.1136/gut.2003.036657 [Abstract] [Full text] [PDF] [Request Permissions]

Colorectal cancer

BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum
T Kambara, L A Simms, V L J Whitehall, K J Spring, C V A Wynter, M D Walsh, M A Barker, S Arnold, A McGivern, N Matsubara, N Tanaka, T Higuchi, J Young, J R Jass, and B A Leggett
Gut 2004; 53: 1137-1144. doi:10.1136/gut.2003.037671 [Abstract] [Full text] [PDF] [Request Permissions]

Glucagon-like peptide 2 (GLP-2) accelerates the growth of colonic neoplasms in mice
J Thulesen, B Hartmann, K J Hare, H Kissow, C Ørskov, J J Holst, and S S Poulsen
Gut 2004; 53: 1145-1150. doi:10.1136/gut.2003.035212 [Abstract] [Full text] [PDF] [Request Permissions]

Downregulation of prostaglandin E receptor subtype EP₃ during colon cancer development
Y Shoji, M Takahashi, T Kitamura, K Watanabe, T Kawamori, T Maruyama, Y Sugimoto, M Negishi, S Narumiya, T Sugimura, and K Wakabayashi
Gut 2004; 53: 1151-1158. doi:10.1136/gut.2003.028787 [Abstract] [Full text] [PDF] [Request Permissions]

Pancreatic cancer

Altered glucose metabolism and proteolysis in pancreatic cancer cell conditioned myoblasts: searching for a gene expression pattern with a microarray analysis of 5000 skeletal muscle genes
D Basso, C Millino, E Greco, C Romualdi, P Fogar, A Valerio, M Bellin, C-F Zambon, F Navaglia, N Dussini, A Avogaro, S Pedrazzoli, G Lanfranchi, and M Plebani
Gut 2004; 53: 1159-1166. doi:10.1136/gut.2003.024471 [Abstract] [Full text] [PDF] [Request Permissions]

Liver

Repeated adenoviral administration into the biliary tract can induce repeated expression of the original gene construct in rat livers without immunosuppressive strategies
K Tominaga, S Kuriyama, H Yoshiji, A Deguchi, Y Kita, F Funakoshi, T Masaki, K Kurokohchi, N Uchida, T Tsujimoto, and H Fukui
Gut 2004; 53: 1167-1173. doi:10.1136/gut.2003.013748 [Abstract] [Full text] [PDF] [Request Permissions]

Increased DMT1 but not IREG1 or HFE mRNA following iron depletion therapy in hereditary haemochromatosis
T Kelleher, E Ryan, S Barrett, M Sweeney, V Byrnes, C O’Keane, and J Crowe
Gut 2004; 53: 1174-1179. doi:10.1136/gut.2003.033811 [Abstract] [Full text] [PDF] [Request Permissions]

Expression of somatostatin receptors in normal and cirrhotic human liver and in hepatocellular carcinoma
H Reynaert, K Rombouts, A Vandermonde, D Urbain, U Kumar, P Bioulac-Sage, M Pinzani, J Rosenbaum, and A Geerts
Gut 2004; 53: 1180-1189. doi:10.1136/gut.2003.036053 [Abstract] [Full text] [PDF] [Request Permissions]

Reviews

Iron, anaemia, and inflammatory bowel diseases
C Gasche, M C E Lomer, I Cavill, and G Weiss
Gut 2004; 53: 1190-1197. doi:10.1136/gut.2003.035758 [Abstract] [Full text] [PDF] [Request Permissions]

Recent advances in basic science

Brain imaging and functional gastrointestinal disorders: has it helped our understanding?
A R Hobson and Q Aziz
Gut 2004; 53: 1198-1206. doi:10.1136/gut.2003.035642 [Extract] [Full text] [PDF] [Request Permissions]

Recent advances in clinical practice

Endoscopic antireflux procedures
J Arts, J Tack, and J P Galmiche
Gut 2004; 53: 1207-1214. doi:10.1136/gut.2003.025460 [Extract] [Full text] [PDF] [Request Permissions]

JournalScan

JournalScan
Gut 2004; 53: 1215. [Extract] [Full text] [PDF] [Request Permissions]

Book reviews

Aging and the Gastrointestinal Tract
O F W James
Gut 2004; 53: 1216. [Extract] [Full text] [PDF] [Request Permissions]

Corrections

CORRECTIONS
Gut 2004; 53: 1216. doi:10.1136/gut.2003.023937corr1 [Extract] [Full text] [PDF] [Request Permissions]

CORRECTIONS
Gut 2004; 53: 1216. doi:10.1136/gut.2003.027789corr1 [Extract] [Full text] [PDF] [Request Permissions]

Cover

Repeated adenoviral administration into the biliary tract (from the paper by Tominaga et al, pp 1167-1173).

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	Effects of growth factors and receptor blockade on gastrointestinal cancer R J Playford, H Wassan, and S Ghosh Gut 2004; 53: 1059-1063. doi:10.1136/gut.2003.038620 [Abstract] [Full text] [PDF] [Request Permissions]

	Digest Robin Spiller Gut 2004; 53: 1059. [Extract] [Full text] [PDF] [Request Permissions]

	A calcified caecal mass A Hokama, T Makishi, R Tomiyama, F Kinjo, A Saito, S Yamashiro, I Kinjo, K Miyagi, Y Kuniyoshi, and K Koja Gut 2004; 53: 1063. doi:10.1136/gut.2003.034009 [Extract] [Full text] [PDF] [Request Permissions]

	EDITOR’S QUIZ: GI SNAPSHOT Gut 2004; 53: 1081. [Extract] [Full text] [PDF] [Request Permissions]

	A male with a pelvic mass K T Kjossev, N N Vladov, and J E Losanoff Gut 2004; 53: 1122. doi:10.1136/gut.2003.024638 [Extract] [Full text] [PDF] [Request Permissions]

	EDITOR’S QUIZ: GI SNAPSHOT Gut 2004; 53: 1144. [Extract] [Full text] [PDF] [Request Permissions]

	An unusual case of abdominal pain N Yazaki, K Shiiba, S Ishii, T Mizoi, K Miura, A Oyama, N Tanaka, Y Murata, and I Sasaki Gut 2004; 53: 1150. doi:10.1136/gut.2003.023929 [Extract] [Full text] [PDF] [Request Permissions]

	EDITOR’S QUIZ: GI SNAPSHOT Gut 2004; 53: 1158. [Extract] [Full text] [PDF] [Request Permissions]

	Oesophageal cancer and gastro-oesophageal reflux: what is the relationship? J Lagergren Gut 2004; 53: 1064-1065. doi:10.1136/gut.2003.038471 [Extract] [Full text] [PDF] [Request Permissions]

	T helper cell polarisation in coeliac disease: any (T-)bet ? M H Holtmann and M F Neurath Gut 2004; 53: 1065-1067. doi:10.1136/gut.2003.038232 [Extract] [Full text] [PDF] [Request Permissions]

	East meets West: infection, nerves, and mast cells in the irritable bowel syndrome S M Collins and G Barbara Gut 2004; 53: 1068-1069. doi:10.1136/gut.2004.038893 [Extract] [Full text] [PDF] [Request Permissions]

	Risk of oesophageal cancer in Barrett’s oesophagus and gastro-oesophageal reflux M Solaymani-Dodaran, R F A Logan, J West, T Card, and C Coupland Gut 2004; 53: 1070-1074. doi:10.1136/gut.2003.028076 [Abstract] [Full text] [PDF] [Request Permissions]

	Effect of Th1 cytokines on acid secretion in pharmacologically characterised mouse gastric glands I T Padol and R H Hunt Gut 2004; 53: 1075-1081. doi:10.1136/gut.2003.026435 [Abstract] [Full text] [PDF] [Request Permissions]

	*Cytokine gene polymorphisms influence mucosal cytokine expression, gastric inflammation, and host specific colonisation during Helicobacter pylori* infection** R Rad, A Dossumbekova, B Neu, R Lang, S Bauer, D Saur, M Gerhard, and C Prinz Gut 2004; 53: 1082-1089. doi:10.1136/gut.2003.029736 [Abstract] [Full text] [PDF] [Request Permissions]

	Regulation of the T helper cell type 1 transcription factor T-bet in coeliac disease mucosa I Monteleone, G Monteleone, G Del Vecchio Blanco, P Vavassori, S Cucchiara, T T MacDonald, and F Pallone Gut 2004; 53: 1090-1095. doi:10.1136/gut.2003.030551 [Abstract] [Full text] [PDF] [Request Permissions]

	Bacillary dysentery as a causative factor of irritable bowel syndrome and its pathogenesis L-H Wang, X-C Fang, and G-Z Pan Gut 2004; 53: 1096-1101. doi:10.1136/gut.2003.021154 [Abstract] [Full text] [PDF] [Request Permissions]

	Altered visceral perceptual and neuroendocrine response in patients with irritable bowel syndrome during mental stress I Posserud, P Agerforz, R Ekman, E S Björnsson, H Abrahamsson, and M Simrén Gut 2004; 53: 1102-1108. doi:10.1136/gut.2003.017962 [Abstract] [Full text] [PDF] [Request Permissions]

	Chemical nociception in the jejunum induced by capsaicin B Schmidt, J Hammer, P Holzer, and H F Hammer Gut 2004; 53: 1109-1116. doi:10.1136/gut.2003.029793 [Abstract] [Full text] [PDF] [Request Permissions]

	*Anti-Saccharomyces cerevisiae* antibody (ASCA) positivity is associated with increased risk for early surgery in Crohn’s disease** D G Forcione, M J Rosen, J B Kisiel, and B E Sands Gut 2004; 53: 1117-1122. doi:10.1136/gut.2003.030734 [Abstract] [Full text] [PDF] [Request Permissions]

	Clinical significance of azathioprine active metabolite concentrations in inflammatory bowel disease S Wright, D S Sanders, A J Lobo, and L Lennard Gut 2004; 53: 1123-1128. doi:10.1136/gut.2003.032896 [Abstract] [Full text] [PDF] [Request Permissions]

	Measurement of vitamin D levels in inflammatory bowel disease patients reveals a subset of Crohn’s disease patients with elevated 1,25-dihydroxyvitamin D and low bone mineral density M T Abreu, V Kantorovich, E A Vasiliauskas, U Gruntmanis, R Matuk, K Daigle, S Chen, D Zehnder, Y-C Lin, H Yang, M Hewison, and J S Adams Gut 2004; 53: 1129-1136. doi:10.1136/gut.2003.036657 [Abstract] [Full text] [PDF] [Request Permissions]

	BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum T Kambara, L A Simms, V L J Whitehall, K J Spring, C V A Wynter, M D Walsh, M A Barker, S Arnold, A McGivern, N Matsubara, N Tanaka, T Higuchi, J Young, J R Jass, and B A Leggett Gut 2004; 53: 1137-1144. doi:10.1136/gut.2003.037671 [Abstract] [Full text] [PDF] [Request Permissions]

	Glucagon-like peptide 2 (GLP-2) accelerates the growth of colonic neoplasms in mice J Thulesen, B Hartmann, K J Hare, H Kissow, C Ørskov, J J Holst, and S S Poulsen Gut 2004; 53: 1145-1150. doi:10.1136/gut.2003.035212 [Abstract] [Full text] [PDF] [Request Permissions]

	Downregulation of prostaglandin E receptor subtype EP₃ during colon cancer development Y Shoji, M Takahashi, T Kitamura, K Watanabe, T Kawamori, T Maruyama, Y Sugimoto, M Negishi, S Narumiya, T Sugimura, and K Wakabayashi Gut 2004; 53: 1151-1158. doi:10.1136/gut.2003.028787 [Abstract] [Full text] [PDF] [Request Permissions]

	Repeated adenoviral administration into the biliary tract can induce repeated expression of the original gene construct in rat livers without immunosuppressive strategies K Tominaga, S Kuriyama, H Yoshiji, A Deguchi, Y Kita, F Funakoshi, T Masaki, K Kurokohchi, N Uchida, T Tsujimoto, and H Fukui Gut 2004; 53: 1167-1173. doi:10.1136/gut.2003.013748 [Abstract] [Full text] [PDF] [Request Permissions]

	Increased DMT1 but not IREG1 or HFE mRNA following iron depletion therapy in hereditary haemochromatosis T Kelleher, E Ryan, S Barrett, M Sweeney, V Byrnes, C O’Keane, and J Crowe Gut 2004; 53: 1174-1179. doi:10.1136/gut.2003.033811 [Abstract] [Full text] [PDF] [Request Permissions]

	Expression of somatostatin receptors in normal and cirrhotic human liver and in hepatocellular carcinoma H Reynaert, K Rombouts, A Vandermonde, D Urbain, U Kumar, P Bioulac-Sage, M Pinzani, J Rosenbaum, and A Geerts Gut 2004; 53: 1180-1189. doi:10.1136/gut.2003.036053 [Abstract] [Full text] [PDF] [Request Permissions]

	Iron, anaemia, and inflammatory bowel diseases C Gasche, M C E Lomer, I Cavill, and G Weiss Gut 2004; 53: 1190-1197. doi:10.1136/gut.2003.035758 [Abstract] [Full text] [PDF] [Request Permissions]

	Brain imaging and functional gastrointestinal disorders: has it helped our understanding? A R Hobson and Q Aziz Gut 2004; 53: 1198-1206. doi:10.1136/gut.2003.035642 [Extract] [Full text] [PDF] [Request Permissions]

	Endoscopic antireflux procedures J Arts, J Tack, and J P Galmiche Gut 2004; 53: 1207-1214. doi:10.1136/gut.2003.025460 [Extract] [Full text] [PDF] [Request Permissions]

	JournalScan Gut 2004; 53: 1215. [Extract] [Full text] [PDF] [Request Permissions]

	Aging and the Gastrointestinal Tract O F W James Gut 2004; 53: 1216. [Extract] [Full text] [PDF] [Request Permissions]

	CORRECTIONS Gut 2004; 53: 1216. doi:10.1136/gut.2003.023937corr1 [Extract] [Full text] [PDF] [Request Permissions]

	CORRECTIONS Gut 2004; 53: 1216. doi:10.1136/gut.2003.027789corr1 [Extract] [Full text] [PDF] [Request Permissions]