Leading articles

	Relevance of volume and proximal extent of reflux in gastro-oesophageal reflux disease D Sifrim Gut 2005; 54: 175-178. doi:10.1136/gut.2004.043984 [Abstract] [Full text] [PDF] [Request Permissions]

Digest

	Digest Robin Spiller Gut 2005; 54: 175. [Extract] [Full text] [PDF] [Request Permissions]

Miscellanea

	Caecal tumour with hepatic metastases? S Rajendra and K Kutty Gut 2005; 54: 178. doi:10.1136/gut.2004.046102 [Extract] [Full text] [PDF] [Request Permissions]
	Black oesophagus—cause? A Sako, J Kitayama, T Inoue, S Kaizaki, H Nagawa, and H Suzuki Gut 2005; 54: 192. doi:10.1136/gut.2004.044784 [Extract] [Full text] [PDF] [Request Permissions]
	EDITOR’S QUIZ: GI SNAPSHOT Gut 2005; 54: 200. [Extract] [Full text] [PDF] [Request Permissions]
	An unusual CT S Baydar, A Hatipoglu, A Sezer, C Ibis, I Coskun, H Umit, and A Tezel Gut 2005; 54: 206. doi:10.1136/gut.2004.046441 [Extract] [Full text] [PDF] [Request Permissions]
	Chronic intermittent vomiting after scoliosis surgery A Hokama, R Tomiyama, K Kishimoto, F Kinjo, A Saito, and M Matayoshi Gut 2005; 54: 222. doi:10.1136/gut.2004.044313 [Extract] [Full text] [PDF] [Request Permissions]
	EDITOR’S QUIZ: GI SNAPSHOT Gut 2005; 54: 227. [Extract] [Full text] [PDF] [Request Permissions]
	EDITOR’S QUIZ: GI SNAPSHOT Gut 2005; 54: 249. [Extract] [Full text] [PDF] [Request Permissions]
	EDITOR’S QUIZ: GI SNAPSHOT Gut 2005; 54: 281. [Extract] [Full text] [PDF] [Request Permissions]
	Gut Tutorial: chronic diarrhoea Gut 2005; 54: 296. [Extract] [Full text] [PDF] [Request Permissions]   BMJ Learning: Take this module on BMJ Learning

Commentaries

	Gatekeeper reflux repair system; a mechanistic hypothesis P J Kahrilas and T J Lee Gut 2005; 54: 179-180. doi:10.1136/gut.2004.051805 [Extract] [Full text] [PDF] [Request Permissions]
	Granuloma formation in the different phenotypes of Crohn’s disease F Hofstaedter Gut 2005; 54: 180-181. doi:10.1136/gut.2004.048082 [Extract] [Full text] [PDF] [Request Permissions]
	Value of MR colonography for assessment of inflammatory bowel disease? Believe what you see—see what you believe C Gasche and K Turetschek Gut 2005; 54: 181-182. doi:10.1136/gut.2004.044982 [Extract] [Full text] [PDF] [Request Permissions]

Gastro-oesophageal reflux

	Effect of endoscopic augmentation of the lower oesophageal sphincter (Gatekeeper reflux repair system) on intraoesophageal dynamic characteristics of acid reflux M Cicala, A Gabbrielli, S Emerenziani, M P L Guarino, M Ribolsi, R Caviglia, and G Costamagna Gut 2005; 54: 183-186. doi:10.1136/gut.2004.040501 [Abstract] [Full text] [PDF] [Request Permissions]

Oesophageal cancer

	Histological precursors of oesophageal squamous cell carcinoma: results from a 13 year prospective follow up study in a high risk population G-Q Wang, C C Abnet, Q Shen, K J Lewin, X-D Sun, M J Roth, Y-L Qiao, S D Mark, Z-W Dong, P R Taylor, and S M Dawsey Gut 2005; 54: 187-192. doi:10.1136/gut.2004.046631 [Abstract] [Full text] [PDF] [Request Permissions]

Stomach

	Apple polyphenol extracts prevent damage to human gastric epithelial cells in vitro and to rat gastric mucosa in vivo G Graziani, G D’Argenio, C Tuccillo, C Loguercio, A Ritieni, F Morisco, C Del Vecchio Blanco, V Fogliano, and M Romano Gut 2005; 54: 193-200. doi:10.1136/gut.2004.046292 [Abstract] [Full text] [PDF] [Request Permissions]

Gastric cancer

	Reduced expression of epidermal growth factor receptor related protein in gastric cancer W S Moon, A S Tarnawski, J Chai, J T Yang, and A P N Majumdar Gut 2005; 54: 201-206. doi:10.1136/gut.2003.027078 [Abstract] [Full text] [PDF] [Request Permissions]

Inflammation

	Regulatory CD4+CD25+ cells reverse imbalances in the T cell pool of bone marrow transplanted TG26 mice leading to the prevention of colitis C Veltkamp, R B Sartor, T Giese, F Autschbach, I Kaden, R Veltkamp, D Rost, B Kallinowski, and W Stremmel Gut 2005; 54: 207-214. doi:10.1136/gut.2004.046953 [Abstract] [Full text] [PDF] [Request Permissions]

Inflammatory bowel disease

	Frequency and significance of granulomas in a cohort of incident cases of Crohn’s disease D Heresbach, J L Alexandre, B Branger, J F Bretagne, E Cruchant, A Dabadie, M Dartois-Hoguin, P M Girardot, H Jouanolle, J Kerneis, J C Le Verger, V Louvain, J Politis, M Richecoeur, M Robaszkiewicz, J A Seyrig the ABERMAD Gut 2005; 54: 215-222. doi:10.1136/gut.2004.041715 [Abstract] [Full text] [PDF] [Request Permissions]
	Epithelioid granulomas, pattern recognition receptors, and phenotypes of Crohn’s disease M Pierik, G De Hertogh, S Vermeire, G Van Assche, P Van Eyken, S Joossens, G Claessens, R Vlietinck, P Rutgeerts, and K Geboes Gut 2005; 54: 223-227. doi:10.1136/gut.2004.042572 [Abstract] [Full text] [PDF] [Request Permissions]
	Patients with active inflammatory bowel disease lack immature peripheral blood plasmacytoid and myeloid dendritic cells D C Baumgart, D Metzke, J Schmitz, A Scheffold, A Sturm, B Wiedenmann, and A U Dignass Gut 2005; 54: 228-236. doi:10.1136/gut.2004.040360 [Abstract] [Full text] [PDF] [Request Permissions]
	Impact of the increasing use of immunosuppressants in Crohn’s disease on the need for intestinal surgery J Cosnes, I Nion-Larmurier, L Beaugerie, P Afchain, E Tiret, and J-P Gendre Gut 2005; 54: 237-241. doi:10.1136/gut.2004.045294 [Abstract] [Full text] [Complete Version: Including Figure 2] [PDF] [Request Permissions]
	Synbiotic therapy (Bifidobacterium longum/Synergy 1) initiates resolution of inflammation in patients with active ulcerative colitis: a randomised controlled pilot trial E Furrie, S Macfarlane, A Kennedy, J H Cummings, S V Walsh, D A O’Neil, and G T Macfarlane Gut 2005; 54: 242-249. doi:10.1136/gut.2004.044834 [Abstract] [Full text] [PDF] [Request Permissions]
	Comparison of magnetic resonance imaging colonography with conventional colonoscopy for the assessment of intestinal inflammation in patients with inflammatory bowel disease: a feasibility study A G Schreyer, H C Rath, R Kikinis, M Völk, J Schölmerich, S Feuerbach, G Rogler, J Seitz, and H Herfarth Gut 2005; 54: 250-256. doi:10.1136/gut.2003.037390 [Abstract] [Full text] [PDF] [Request Permissions]
	Magnetic resonance colonography for the detection of inflammatory diseases of the large bowel: quantifying the inflammatory activity W M Ajaj, T C Lauenstein, G Pelster, G Gerken, S G Ruehm, J F Debatin, and S C Goehde Gut 2005; 54: 257-263. doi:10.1136/gut.2003.037085 [Abstract] [Full text] [PDF] [Request Permissions]

Colorectal cancer

	Exon 3 ß-catenin mutations are specifically associated with colorectal carcinomas in hereditary non-polyposis colorectal cancer syndrome V Johnson, E Volikos, S E Halford, E T Eftekhar Sadat, S Popat, I Talbot, K Truninger, J Martin, J Jass, R Houlston, W Atkin, I P M Tomlinson, and A R J Silver Gut 2005; 54: 264-267. doi:10.1136/gut.2004.048132 [Abstract] [Full text] [PDF] [Request Permissions]
	Survival differences between European and US patients with colorectal cancer: role of stage at diagnosis and surgery L Ciccolallo, R Capocaccia, M P Coleman, F Berrino, J W W Coebergh, R A M Damhuis, J Faivre, C Martinez-Garcia, H Møller, M Ponz de Leon, G Launoy, N Raverdy, E M I Williams, and G Gatta Gut 2005; 54: 268-273. doi:10.1136/gut.2004.044214 [Abstract] [Full text] [PDF] [Request Permissions]

Pancreas

	Serum antibodies to carbonic anhydrase IV in patients with autoimmune pancreatitis I Nishimori, E Miyaji, K Morimoto, K Nagao, M Kamada, and S Onishi Gut 2005; 54: 274-281. doi:10.1136/gut.2004.049064 [Abstract] [Full text] [PDF] [Request Permissions]

Liver

	Effect of central corticotropin releasing factor on hepatic circulation in rats: the role of the CRF2 receptor in the brain M Yoneda, K Nakamura, Y Nakade, M Tamano, T Kono, H Watanobe, T Shimada, H Hiraishi, and A Terano Gut 2005; 54: 282-288. doi:10.1136/gut.2003.036426 [Abstract] [Full text] [PDF] [Request Permissions]
	The value of residual liver volume as a predictor of hepatic dysfunction and infection after major liver resection M J Schindl, D N Redhead, K C H Fearon, O J Garden, S J Wigmore on behalf of the Edinburgh Liver Surgery and Transplantation Experimental Research Group Gut 2005; 54: 289-296. doi:10.1136/gut.2004.046524 [Abstract] [Full text] [PDF] [Request Permissions]
	Changes to hepatocyte ploidy and binuclearity profiles during human chronic viral hepatitis H Toyoda, O Bregerie, A Vallet, B Nalpas, G Pivert, C Brechot, and C Desdouets Gut 2005; 54: 297-302. doi:10.1136/gut.2004.043893 [Abstract] [Full text] [PDF] [Request Permissions]

Recent advances in clinical practice

	Cytokines and the pathogenesis of non-alcoholic steatohepatitis A M Diehl, Z P Li, H Z Lin, and S Q Yang Gut 2005; 54: 303-306. doi:10.1136/gut.2003.024935 [Extract] [Full text] [PDF] [Request Permissions]

JournalScan

	JournalScan Gut 2005; 54: 307. [Extract] [Full text] [PDF] [Request Permissions]

Letters

	Toll-like receptor 4 gene in IBD: further evidence for genetic heterogeneity in Europe • Author’s reply I D R Arnott, G-T Ho, E R Nimmo, J Satsangi, D Franchimont, S Vermeire, J Deviere, and P J Rutgeerts Gut 2005; 54: 308-309. [Extract] [Full text] [PDF] [Request Permissions]
	Portopulmonary hypertension in cirrhosis: the pathogenetic challenge F Wong Gut 2005; 54: 309. [Extract] [Full text] [PDF] [Request Permissions]
	Oesophageal entrapment of wireless capsule endoscopy in valvular patients E Redondo-Cerezo, A Pérez-Sola, C Gómez, G Pérez-Vigara, J I Pérez-García, J Morillas, and J A González-Martín Gut 2005; 54: 309-310. doi:10.1136/gut.2004.051318 [Extract] [Full text] [PDF] [Request Permissions]
	Endogenous heparinoids in acute variceal bleeding U Thalheimer, C Triantos, D Samonakis, D Patch, A K Burroughs, A Riddell, and D Perry Gut 2005; 54: 310-311. doi:10.1136/gut.2004.051474 [Extract] [Full text] [PDF] [Request Permissions]
	Changing epidemiology of IPSID in Southern Iran K B Lankarani, S M Masoompour, M B Masoompour, R Malekzadeh, S Z Tabei, and M Haghshenas Gut 2005; 54: 311-312. doi:10.1136/gut.2004.050526 [Extract] [Full text] [PDF] [Request Permissions]
	Microscopic (collagenous and lymphocytic) colitis triggered by food allergy M Weidenhiller, S Müller, D Schwab, E G Hahn, M Raithel, and S Winterkamp Gut 2005; 54: 312-313. doi:10.1136/gut.2004.049767 [Extract] [Full text] [Conflict of Interest Statement] [PDF] [Request Permissions]
	Acetic acid spray in colonoscopy: an alternative to chromoendoscopy Y J Kawamura, K Togashi, J Sasaki, and F Konishi Gut 2005; 54: 313. [Extract] [Full text] [PDF] [Request Permissions]
	Infliximab failure in cap polyposis V Maunoury, M Breisse, P Desreumaux, L Gambiez, and J-F Colombel Gut 2005; 54: 313-314. doi:10.1136/gut.2004.053686 [Extract] [Full text] [PDF] [Request Permissions]
	Differential modulation of p38 mitogen activated protein kinase and STAT3 signalling pathways by infliximab and etanercept in intestinal T cells from patients with Crohn’s disease • Author’s reply P Rosenstiel, J Agnholt, J Kelsen, V Medici, G H Waetzig, D Seegert, S Schreiber, A Di Sabatino, R Ciccocioppo, R Morera, and G R Corazza Gut 2005; 54: 314-316. [Extract] [Full text] [PDF] [Request Permissions]

Book reviews

	Small and Large Intestine S J Middleton Gut 2005; 54: 316. [Extract] [Full text] [PDF] [Request Permissions]

Corrections

	CORRECTION Gut 2005; 54: 316. doi:10.1136/gut.2003.035113corr1 [Extract] [Full text] [PDF] [Request Permissions]