Leading articles

	Gastrointestinal complications of pelvic radiotherapy: are they of any importance? J Andreyev Gut 2005; 54: 1051-1054. doi:10.1136/gut.2004.062596 [Abstract] [Full text] [PDF] [Request Permissions]

Digest

	Digest Robin Spiller Gut 2005; 54: 1051. [Extract] [Full text] [PDF] [Request Permissions]

Commentaries

	Risks and benefits of azathioprine therapy D P B McGovern and D P Jewell Gut 2005; 54: 1055-1059. doi:10.1136/gut.2004.053231 [Extract] [Full text] [PDF] [Request Permissions]
	5-HT3 receptor antagonists ameliorate fatigue: so much potential, so little knowledge! N M Barnes Gut 2005; 54: 1056-1057. doi:10.1136/gut.2004.063545 [Extract] [Full text] [PDF] [Request Permissions]
	Predicting mortality by the Glasgow alcoholic hepatitis score: the long awaited progress? H Tilg and A Kaser Gut 2005; 54: 1057-1059. doi:10.1136/gut.2004.063420 [Extract] [Full text] [PDF] [Request Permissions]

Clinical @lert

	New IBD genes? D McGovern and T Ahmad Gut 2005; 54: 1060-1061. doi:10.1136/gut.2004.048918 [Abstract] [Full text] [PDF] [Request Permissions]

Miscellanea

	An unusual cause of rectal bleeding in a patient with rheumatoid arthritis A Hokama, K Tanaka, M Nakamoto, N Uchima, F Kinjo, and A Saito Gut 2005; 54: 1061. doi:10.1136/gut.2004.062406 [Extract] [Full text] [PDF] [Request Permissions]
	Answer Gut 2005; 54: 1071. [Extract] [Full text] [PDF] [Request Permissions]
	An unusual case of biliary pain J Boujaoude, B Abboud, M Chemaly, K Hachem, and A Zoughbi Gut 2005; 54: 1106. doi:10.1136/gut.2004.059659 [Extract] [Full text] [PDF] [Request Permissions]
	The radiologist made the diagnosis J R Bebb and K H Latief Gut 2005; 54: 1113. doi:10.1136/gut.2004.063339 [Extract] [Full text] [PDF] [Request Permissions]
	Answer Gut 2005; 54: 1145. [Extract] [Full text] [PDF] [Request Permissions]
	Answer Gut 2005; 54: 1168. [Extract] [Full text] [PDF] [Request Permissions]
	An unusual cause of melena K P Basavaraju, K Armitage, C R Hunt, and N K Ahluwalia Gut 2005; 54: 1180. doi:10.1136/gut.2004.063305 [Extract] [Full text] [PDF] [Request Permissions]
	Answer Gut 2005; 54: 1193. [Extract] [Full text] [PDF] [Request Permissions]

Oesophagus

	Increasing incidence of Barrett’s oesophagus in the general population E M van Soest, J P Dieleman, P D Siersema, M C J M Sturkenboom, and E J Kuipers Gut 2005; 54: 1062-1066. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 27 April 2005. doi:10.1136/gut.2004.063685
	Symptom association probability and symptom sensitivity index: preferable but still suboptimal predictors of response to high dose omeprazole S A Taghavi, M Ghasedi, M Saberi-Firoozi, M Alizadeh-Naeeni, K Bagheri-Lankarani, M J Kaviani, and L Hamidpour Gut 2005; 54: 1067-1071. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 21 April 2005. doi:10.1136/gut.2004.054981
	Diffusion of cytotoxic concentrations of nitric oxide generated luminally at the gastro-oesophageal junction of rats K Asanuma, K Iijima, H Sugata, S Ohara, T Shimosegawa, and T Yoshimura Gut 2005; 54: 1072-1077. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 28 April 2005. doi:10.1136/gut.2004.063107

Gastric motility

	Gastric motor effects of peptide and non-peptide ghrelin agonists in mice in vivo and in vitro T Kitazawa, B De Smet, K Verbeke, I Depoortere, and T L Peeters Gut 2005; 54: 1078-1084. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 20 April 2005. doi:10.1136/gut.2005.065896

Small bowel

	Longitudinal mechanical tension induces growth in the small bowel of juvenile rats S D Safford, A J Freemerman, K M Safford, R Bentley, and M A Skinner Gut 2005; 54: 1085-1090. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 19 April 2005. doi:10.1136/gut.2004.061481

Epithelial cell biology

	Absence of Fer protein tyrosine kinase exacerbates endotoxin induced intestinal epithelial barrier dysfunction in vivo W Qi, K V J Ebbert, A W B Craig, P A Greer, and D-M McCafferty Gut 2005; 54: 1091-1097. doi:10.1136/gut.2004.061887 [Abstract] [Full text] [PDF] [Request Permissions]
	Key role of the sympathetic microenvironment for the interplay of tumour necrosis factor and interleukin 6 in normal but not in inflamed mouse colon mucosa R H Straub, K Stebner, P Härle, F Kees, W Falk, and J Schölmerich Gut 2005; 54: 1098-1106. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 21 April 2005. doi:10.1136/gut.2004.062877

Colonic motility

	Interstitial cells of Cajal are involved in the afferent limb of the rectoanal inhibitory reflex F de Lorijn, W J de Jonge, T Wedel, J M Vanderwinden, M A Benninga, and G E Boeckxstaens Gut 2005; 54: 1107-1113. doi:10.1136/gut.2004.051045 [Abstract] [Full text] [PDF] [Request Permissions]

Inflammatory bowel disease

	Systemic administration of the chemokine macrophage inflammatory protein 1 exacerbates inflammatory bowel disease in a mouse model S L-F Pender, V Chance, C V Whiting, M Buckley, M Edwards, R Pettipher, and T T MacDonald Gut 2005; 54: 1114-1120. doi:10.1136/gut.2004.052779 [Abstract] [Full text] [PDF] [Request Permissions]
	Increased risk of lymphoma among inflammatory bowel disease patients treated with azathioprine and 6-mercaptopurine A Kandiel, A G Fraser, B I Korelitz, C Brensinger, and J D Lewis Gut 2005; 54: 1121-1125. doi:10.1136/gut.2004.049460 [Abstract] [Full text] [Competing interest statement] [PDF] [Request Permissions]
	Dynamics of mucosal permeability and inflammation in collagenous colitis before, during, and after loop ileostomy A Münch, J D Söderholm, C Wallon, Å Öst, G Olaison, and M Ström Gut 2005; 54: 1126-1128. doi:10.1136/gut.2004.058750 [Abstract] [Full text] [PDF] [Request Permissions]

Colon cancer

	NF1 gene loss of heterozygosity and expression analysis in sporadic colon cancer T Cacev, S Radosevic, R Spaventi, K Pavelic, and S Kapitanovic Gut 2005; 54: 1129-1135. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 19 April 2005. doi:10.1136/gut.2004.053348
	Leptin stimulates the proliferation of human colon cancer cells in vitro but does not promote the growth of colon cancer xenografts in nude mice or intestinal tumorigenesis in ApcMin/+ mice T Aparicio, L Kotelevets, A Tsocas, J-P Laigneau, I Sobhani, E Chastre, and T Lehy Gut 2005; 54: 1136-1145. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 27 April 2005. doi:10.1136/gut.2004.060533
	Family history and molecular features of children, adolescents, and young adults with colorectal carcinoma C Durno, M Aronson, B Bapat, Z Cohen, and S Gallinger Gut 2005; 54: 1146-1150. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 21 April 2005. doi:10.1136/gut.2005.066092

Liver

	Randomised controlled trial comparing percutaneous radiofrequency thermal ablation, percutaneous ethanol injection, and percutaneous acetic acid injection to treat hepatocellular carcinoma of 3 cm or less S-M Lin, C-J Lin, C-C Lin, C-W Hsu, and Y-C Chen Gut 2005; 54: 1151-1156. doi:10.1136/gut.2004.045203 [Abstract] [Full text] [PDF] [Request Permissions]

Gut tutorial

	Crohn’s or abdominal tuberculosis? A Forbes Gut 2005; 54: 1156. [Extract] [Full text] [PDF] [Request Permissions]   BMJ Learning: Take this module on BMJ Learning

Viral hepatitis

	The CCR5-32 mutation: impact on disease outcome in individuals with hepatitis C infection from a single source C Goulding, A Murphy, G MacDonald, S Barrett, J Crowe, J Hegarty, S McKiernan, and D Kelleher Gut 2005; 54: 1157-1161. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 29 April 2005. doi:10.1136/gut.2004.055699
	Large scaled analysis of hepatitis B virus (HBV) DNA integration in HBV related hepatocellular carcinomas Y Murakami, K Saigo, H Takashima, M Minami, T Okanoue, C Bréchot, and P Paterlini-Bréchot Gut 2005; 54: 1162-1168. doi:10.1136/gut.2004.054452 [Abstract] [Full text] [Web-only table and figures] [PDF] [Request Permissions]
	Effect of ondansetron, a 5-HT3 receptor antagonist, on fatigue in chronic hepatitis C: a randomised, double blind, placebo controlled study T Piche, G Vanbiervliet, F Cherikh, Z Antoun, P M Huet, E Gelsi, J-F Demarquay, F-X Caroli-Bosc, S Benzaken, M-C Rigault, C Renou, P Rampal, and A Tran Gut 2005; 54: 1169-1173. doi:10.1136/gut.2004.055251 [Abstract] [Full text] [PDF] [Request Permissions]

Alcoholic liver disease

Analysis of factors predictive of mortality in alcoholic hepatitis and derivation and validation of the Glasgow alcoholic hepatitis score E H Forrest, C D J Evans, S Stewart, M Phillips, Y H Oo, N C McAvoy, N C Fisher, S Singhal, A Brind, G Haydon, J O’Grady, C P Day, P C Hayes, L S Murray, and A J Morris Gut 2005; 54: 1174-1179. doi:10.1136/gut.2004.050781 [Abstract] [Full text] [PDF] [Request Permissions]

JournalScan

	JournalScan Gut 2005; 54: 1181. [Extract] [Full text] [PDF] [Request Permissions]

Recent advances in basic science

	BACTERIAL INTERACTIONS WITH CELLS OF THE INTESTINAL MUCOSA: TOLL-LIKE RECEPTORS AND NOD2 E Cario Gut 2005; 54: 1182-1193. [Extract] [Full text] [PDF] [Request Permissions]   Published Online First: 19 April 2005. doi:10.1136/gut.2004.062794

Recent advances in clinical practice

	CHEMORADIOTHERAPY FOR COLORECTAL CANCER N Andre and W Schmiegel Gut 2005; 54: 1194-1202. doi:10.1136/gut.2004.062745 [Extract] [Full text] [Competing interest statement] [PDF] [Request Permissions]

Letters

	Food elimination in IBS: the case for IgG testing remains doubtful • Author’s reply J O Hunter, P J Whorwell, W Atkinson, and T A Sheldon Gut 2005; 54: 1203. [Extract] [Full text] [Competing interest statement] [PDF] [Request Permissions]
	IgG antibodies to foods in IBS P J Whorwell, K J Bentley, W Atkinson, and T A Sheldon Gut 2005; 54: 1204. [Extract] [Full text] [PDF] [Request Permissions]
	Two models better than one • Author’s reply C Hur, N S Nishioka, G S Gazelle, and N J Shaheen Gut 2005; 54: 1204. [Extract] [Full text] [PDF] [Request Permissions]
	When acquired thrombophilia mattered J S Hammond, L Jackson, A B Zaitoun, B J Rowlands, and G P Aithal Gut 2005; 54: 1204-1205. doi:10.1136/gut.2005.069740 [Extract] [Full text] [PDF] [Request Permissions]
	No association of the NFKB1 promoter polymorphism with ulcerative colitis in a British case control cohort M M Mirza, S A Fisher, C Onnie, C M Lewis, C G Mathew, J Sanderson, and A Forbes Gut 2005; 54: 1205-1206. doi:10.1136/gut.2005.070029 [Extract] [Full text] [PDF] [Request Permissions]
	Primary intestinal autoimmune disease as a cause of chronic intestinal pseudo-obstruction S Ghirardo, B Sauter, G Levy, I M Fiel, T Schiano, and G Gondolesi Gut 2005; 54: 1206-1207. doi:10.1136/gut.2005.069005 [Extract] [Full text] [PDF] [Request Permissions]
	HCV genotype 2 as a risk factor for reactivation of chronic HCV infection N Coppola, L M Vatiero, and E Sagnelli Gut 2005; 54: 1207. doi:10.1136/gut.2005.070649 [Extract] [Full text] [PDF] [Request Permissions]
	Management of acute pancreatitis O M Jolobe Gut 2005; 54: 1207-1208. doi:10.1136/gut.2005.070631 [Extract] [Full text] [Request Permissions]

Book reviews

	Kirsner’s Inflammatory Bowel Disease, 6th edn D A van Heel Gut 2005; 54: 1208. doi:10.1136/gut.2005.066704 [Extract] [Full text] [PDF] [Request Permissions]

Corrections

	CORRECTION Gut 2005; 54: 1208. [Extract] [Full text] [PDF] [Request Permissions]