Leading articles

	Endocannabinoid overactivity and intestinal inflammation V Di Marzo and A A Izzo Gut 2006; 55: 1373-1376. doi:10.1136/gut.2005.090472 [Abstract] [Full text] [PDF] [Request Permissions]

Digest

	Digest Robin Spiller Gut 2006; 55: 1373. [Extract] [Full text] [PDF] [Request Permissions]

Commentaries

	Drinking from the fountain of promise: biomarkers in the surveillance of Barrett’s oesophagus—the glass is half full! S L Preston and J A Jankowski Gut 2006; 55: 1377-1379. doi:10.1136/gut.2006.096461 [Extract] [Full text] [PDF] [Request Permissions]
	Impedance-pH monitoring in proton pump inhibitor resistant patients: ready for clinical application? J P Galmiche Gut 2006; 55: 1379-1381. doi:10.1136/gut.2006.098806 [Extract] [Full text] [PDF] [Request Permissions]
	Hypnosis for non-cardiac chest pain O S Palsson and W E Whitehead Gut 2006; 55: 1381-1384. doi:10.1136/gut.2006.095489 [Extract] [Full text] [PDF] [Request Permissions]
	Another important function for an old friend! The role of iron in colorectal carcinogenesis J R Butterworth Gut 2006; 55: 1384-1386. doi:10.1136/gut.2006.098350 [Extract] [Full text] [PDF] [Request Permissions]
	Folate: a magic bullet or a double edged sword for colorectal cancer prevention? Y-I Kim Gut 2006; 55: 1387-1389. doi:10.1136/gut.2006.095463 [Extract] [Full text] [PDF] [Request Permissions]

Oesophagus

	TP53 and progression from Barrett’s metaplasia to oesophageal adenocarcinoma in a UK population cohort L Murray, A Sedo, M Scott, D McManus, J M Sloan, L J Hardie, D Forman, and C P Wild Gut 2006; 55: 1390-1397. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 8 May 2006. doi:10.1136/gut.2005.083295
	Acid and non-acid reflux in patients with persistent symptoms despite acid suppressive therapy: a multicentre study using combined ambulatory impedance-pH monitoring I Mainie, R Tutuian, S Shay, M Vela, X Zhang, D Sifrim, and D O Castell Gut 2006; 55: 1398-1402. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 23 March 2006. doi:10.1136/gut.2005.087668

Miscellanea

	An unusual cause of rectal bleeding K P Basavaraju, R J Hale, and N K Ahluwalia Gut 2006; 55: 1402. doi:10.1136/gut.2005.088666 [Extract] [Full text] [PDF] [Request Permissions]
	Answer Gut 2006; 55: 1408. [Extract] [Full text] [PDF] [Request Permissions]
	Weight loss and an abdominal mass after resection of a lung carcinoma T Kiyokawa, Y Asato, Y Komuro, J Imura, F Yoshimi, and R Amemiya Gut 2006; 55: 1422. doi:10.1136/gut.2005.090035 [Extract] [Full text] [PDF] [Request Permissions]
	Unusual findings in the biliary tract N Ueno, Y Kawaguchi, I Kawana, and S Umemura Gut 2006; 55: 1435. doi:10.1136/gut.2005.086520 [Extract] [Full text] [PDF] [Request Permissions]
	Answer Gut 2006; 55: 1439. [Extract] [Full text] [PDF] [Request Permissions]
	A case of a "fragile" oesophagus G K Anagnostopoulos, T Shonde, P Kaye, and K Ragunath Gut 2006; 55: 1495. doi:10.1136/gut.2006.091579 [Extract] [Full text] [PDF] [Request Permissions]
	Answer Gut 2006; 55: 1511. [Extract] [Full text] [PDF] [Request Permissions]
	Answer Gut 2006; 55: 1528. [Extract] [Full text] [PDF] [Request Permissions]

Neurogastroenterology

	Treatment of non-cardiac chest pain: a controlled trial of hypnotherapy H Jones, P Cooper, V Miller, N Brooks, and P J Whorwell Gut 2006; 55: 1403-1408. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 20 April 2006. doi:10.1136/gut.2005.086694
	Meal induced rectosigmoid tone modification: a low caloric meal accurately separates functional and organic gastrointestinal disease patients M Di Stefano, E Miceli, A Missanelli, S Mazzocchi, and G R Corazza Gut 2006; 55: 1409-1414. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 24 January 2006. doi:10.1136/gut.2005.076323

Inflammatory bowel disease

	Crucial role of the melanocortin receptor MC1R in experimental colitis C Maaser, K Kannengiesser, C Specht, A Lügering, T Brzoska, T A Luger, W Domschke, and T Kucharzik Gut 2006; 55: 1415-1422. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 16 March 2006. doi:10.1136/gut.2005.083634
	Pharmacogenetics during standardised initiation of thiopurine treatment in inflammatory bowel disease U Hindorf, M Lindqvist, C Peterson, P Söderkvist, M Ström, H Hjortswang, A Pousette, and S Almer Gut 2006; 55: 1423-1431. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 16 March 2006. doi:10.1136/gut.2005.074930
	Narrow band imaging with magnification for dysplasia detection and pit pattern assessment in ulcerative colitis surveillance: a case with multiple dysplasia associated lesions or masses J E East, N Suzuki, A von Herbay, and B P Saunders Gut 2006; 55: 1432-1435. doi:10.1136/gut.2005.087171 [Abstract] [Full text] [PDF] [Request Permissions]

Colorectal cancer

	Abnormal oral mucosal light reflectance: a new clinical marker of high risk for colorectal cancer C De Felice, M Gentile, A Barducci, A Bellosi, S Parrini, G Chitano, and G Latini Gut 2006; 55: 1436-1439. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 9 February 2006. doi:10.1136/gut.2005.083618
	Disease severity and genetic pathways in attenuated familial adenomatous polyposis vary greatly but depend on the site of the germline mutation O M Sieber, S Segditsas, A L Knudsen, J Zhang, J Luz, A J Rowan, S L Spain, C Thirlwell, K M Howarth, E E M Jaeger, J Robinson, E Volikos, A Silver, G Kelly, S Aretz, I Frayling, P Hutter, M Dunlop, T Guenther, K Neale, R Phillips, K Heinimann, and I P M Tomlinson Gut 2006; 55: 1440-1448. [Abstract] [Full text] [web only tables] [PDF] [Request Permissions]   Published Online First: 4 February 2006. doi:10.1136/gut.2005.087106
	Modulation of iron transport proteins in human colorectal carcinogenesis M J Brookes, S Hughes, F E Turner, G Reynolds, N Sharma, T Ismail, G Berx, A T McKie, N Hotchin, G J Anderson, T Iqbal, and C Tselepis Gut 2006; 55: 1449-1460. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 26 April 2006. doi:10.1136/gut.2006.094060
	Low folate levels may protect against colorectal cancer B Van Guelpen, J Hultdin, I Johansson, G Hallmans, R Stenling, E Riboli, A Winkvist, and R Palmqvist Gut 2006; 55: 1461-1466. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 25 April 2006. doi:10.1136/gut.2005.085480
	Extensive DNA methylation in normal colorectal mucosa in hyperplastic polyposis P Minoo, K Baker, R Goswami, G Chong, W D Foulkes, A R Ruszkiewicz, M Barker, D Buchanan, J Young, and J R Jass Gut 2006; 55: 1467-1474. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 9 February 2006. doi:10.1136/gut.2005.082859

Hepatitis

	The hepatitis C virus and immune evasion: non-structural 3/4A transgenic mice are resistant to lethal tumour necrosis factor mediated liver disease L Frelin, E D Brenndörfer, G Ahlén, M Weiland, C Hultgren, M Alheim, H Glaumann, B Rozell, D R Milich, J G Bode, and M Sällberg Gut 2006; 55: 1475-1483. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 9 March 2006. doi:10.1136/gut.2005.085050
	Diminished frequency of hepatitis C virus specific interferon secreting CD4+ T cells in human immunodeficiency virus/hepatitis C virus coinfected patients G Harcourt, E Gomperts, S Donfield, P Klenerman the Hemophilia Growth and Development Study Gut 2006; 55: 1484-1487. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 16 March 2006. doi:10.1136/gut.2005.083758
	Resistance to adefovir dipivoxil in lamivudine resistant chronic hepatitis B patients treated with adefovir dipivoxil J E Yeon, W Yoo, S P Hong, Y J Chang, S K Yu, J H Kim, Y S Seo, H J Chung, M S Moon, S-O Kim, K S Byun, and C H Lee Gut 2006; 55: 1488-1495. [Abstract] [Full text] [web only table][conflict of interest] [PDF] [Request Permissions]   Published Online First: 4 February 2006. doi:10.1136/gut.2005.077099

JournalScan

	JournalScan Gut 2006; 55: 1496. [Extract] [Full text] [PDF] [Request Permissions]

Recent advances in basic science

	Antiangiogenic therapy in human gastrointestinal malignancies J Heidemann, D G Binion, W Domschke, and T Kucharzik Gut 2006; 55: 1497-1511. doi:10.1136/gut.2005.088229 [Extract] [Full text] [PDF] [Request Permissions]

Recent advances in clinical practice

	Alterations in intestinal permeability M C Arrieta, L Bistritz, and J B Meddings Gut 2006; 55: 1512-1520. doi:10.1136/gut.2005.085373 [Extract] [Full text] [conflict of interest] [PDF] [Request Permissions]

Letters

	Long term suppressive therapy with pegylated interferon for chronic hepatitis C associated membranoproliferative glomerulonephritis I H Y Cua, V Kwan, M Henriquez, J Kench, and J George Gut 2006; 55: 1521-1522. doi:10.1136/gut.2006.094508 [Extract] [Full text] [PDF] [Request Permissions]
	Diagnosis of lymphogranuloma venereum from biopsy samples I M C Martin, S A Alexander, C A Ison, N Macdonald, K McCarthy, and H Ward Gut 2006; 55: 1522-1523. doi:10.1136/gut.2006.096370 [Extract] [Full text] [PDF] [Request Permissions]
	Efficacy of ecabet sodium enema on steroid resistant or steroid dependent ulcerative colitis M Iizuka, H Itou, S Konno, T Shirasaka, Y Horie, K Shindo, and S Watanabe Gut 2006; 55: 1523. doi:10.1136/gut.2006.099440 [Extract] [Full text] [PDF] [Request Permissions]
	EUS could detect ascites missed by CT scan • Author’s reply K-M Chu, Y T Lee, and E K W Ng Gut 2006; 55: 1524. [Extract] [Full text] [PDF] [Request Permissions]
	Anti-TNF- therapy for orofacial granulomatosis: proceed with caution D R Gaya, S Aitken, J Fennell, J Satsangi, and A G Shand Gut 2006; 55: 1524-1525. doi:10.1136/gut.2006.099143 [Extract] [Full text] [PDF] [Request Permissions]
	Adverse events in clinical trials with azathioprine and mesalamine for prevention of postoperative recurrence of Crohn’s disease H Herfarth, C Tjaden, M Lukas, F Obermeier, K Dilger, R Müller, J Schölmerich A Z T-1 Study Group Gut 2006; 55: 1525-1526. [Extract] [Full text] [PDF] [Request Permissions]
	Impaired portal circulation resulting from L-arginine deficiency in patients with lysinuric protein intolerance T Takeda, H Watanabe, T Saito, K Saito, H Takeda, H Togashi, J Fujii, Y Takasago, and S Kawata Gut 2006; 55: 1526-1527. doi:10.1136/gut.2005.086603 [Extract] [Full text] [PDF] [Request Permissions]
	Association study of TNFSF15 polymorphisms in Japanese patients with inflammatory bowel disease Y Kakuta, Y Kinouchi, K Negoro, S Takahashi, and T Shimosegawa Gut 2006; 55: 1527-1528. doi:10.1136/gut.2006.100297 [Extract] [Full text] [PDF] [Request Permissions]