Leading articles

	Gastrointestinal endoscopy: past and future M V Sivak Gut 2006; 55: 1061-1064. doi:10.1136/gut.2005.086371 [Abstract] [Full text] [PDF] [Request Permissions]

Digest

	Digest Robin Spiller and Alastair Watson Gut 2006; 55: 1061. [Extract] [Full text] [PDF] [Request Permissions]

Miscellanea

	A unusual cause of anaemia G Neumayr and G Kuehebacher Gut 2006; 55: 1064. doi:10.1136/gut.2005.087023 [Extract] [Full text] [PDF] [Request Permissions]
	Answer Gut 2006; 55: 1077. [Extract] [Full text] [PDF] [Request Permissions]
	Ingested foreign body, to remove or not to remove M K Shariff, K Oppong, and N Thompson Gut 2006; 55: 1103. doi:10.1136/gut.2005.083543 [Extract] [Full text] [PDF] [Request Permissions]
	An unusual cause of abdominal pain M J Williams, S Chippington, J Lund, and A F Goddard Gut 2006; 55: 1123. doi:10.1136/gut.2005.085993 [Extract] [Full text] [PDF] [Request Permissions]
	An unusual chest infection S Logathanan, A Leonard, P Kakar, S Kiani, and S Y Iftikhar Gut 2006; 55: 1130. doi:10.1136/gut.2005.084947 [Extract] [Full text] [PDF] [Request Permissions]
	Answer Gut 2006; 55: 1137. [Extract] [Full text] [PDF] [Request Permissions]
	Answer Gut 2006; 55: 1155. [Extract] [Full text] [PDF] [Request Permissions]
	Answer Gut 2006; 55: 1164. [Extract] [Full text] [PDF] [Request Permissions]

Commentaries

	How do SSRIs help patients with irritable bowel syndrome? F Creed Gut 2006; 55: 1065-1067. doi:10.1136/gut.2005.086348 [Extract] [Full text] [Competing interest statement] [PDF] [Request Permissions]
	Significance of anti-inflammatory effects of PPAR agonists? G Rogler Gut 2006; 55: 1067-1069. doi:10.1136/gut.2005.089946 [Extract] [Full text] [PDF] [Request Permissions]
	Recurrence rates in Crohn’s disease: predicting the future and predicting the past D B Sachar Gut 2006; 55: 1069-1070. doi:10.1136/gut.2005.088658 [Extract] [Full text] [PDF] [Request Permissions]
	Interfering with interferons in inflammatory bowel disease S Ghosh, R Chaudhary, M Carpani, and R Playford Gut 2006; 55: 1071-1073. doi:10.1136/gut.2005.090134 [Extract] [Full text] [PDF] [Request Permissions]
	Human hepatic stellate cells are resistant to apoptosis: implications for human fibrogenic liver disease N Kawada Gut 2006; 55: 1073-1074. doi:10.1136/gut.2005.090449 [Extract] [Full text] [PDF] [Request Permissions]
	Acute hepatitis C virus infection: a neglected disease? W L Irving Gut 2006; 55: 1075-1077. doi:10.1136/gut.2005.085407 [Extract] [Full text] [Competing interest statement] [PDF] [Request Permissions]

Barrett's oesophagus

Elastic scattering spectroscopy accurately detects high grade dysplasia and cancer in Barrett’s oesophagus L B Lovat, K Johnson, G D Mackenzie, B R Clark, M R Novelli, S Davies, M O’Donovan, C Selvasekar, S M Thorpe, D Pickard, R Fitzgerald, T Fearn, I Bigio, and S G Bown Gut 2006; 55: 1078-1083. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 9 February 2006. doi:10.1136/gut.2005.081497

Small intestine

Molecular characterisation of non-absorptive and absorptive enterocytes in human small intestine N Gassler, D Newrzella, C Böhm, S Lyer, L Li, O Sorgenfrei, L van Laer, B Sido, J Mollenhauer, A Poustka, P Schirmacher, and N Gretz Gut 2006; 55: 1084-1089. [Abstract] [Full text] [Web-only tables and figures] [PDF] [Request Permissions]   Published Online First: 23 March 2006. doi:10.1136/gut.2005.073262

Neurogastroenterology

	Lactobacillus farciminis treatment suppresses stress induced visceral hypersensitivity: a possible action through interaction with epithelial cell cytoskeleton contraction A Ait-Belgnaoui, W Han, F Lamine, H Eutamene, J Fioramonti, L Bueno, and V Theodorou Gut 2006; 55: 1090-1094. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 28 February 2006. doi:10.1136/gut.2005.084194
	A controlled crossover study of the selective serotonin reuptake inhibitor citalopram in irritable bowel syndrome J Tack, D Broekaert, B Fischler, L Van Oudenhove, A M Gevers, and J Janssens Gut 2006; 55: 1095-1103. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 9 January 2006. doi:10.1136/gut.2005.077503

Inflammatory bowel disease

	Peroxisome proliferator activated receptor in colonic epithelial cells protects against experimental inflammatory bowel disease M Adachi, R Kurotani, K Morimura, Y Shah, M Sanford, B B Madison, D L Gumucio, H E Marin, J M Peters, H A Young, and F J Gonzalez Gut 2006; 55: 1104-1113. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 17 March 2006. doi:10.1136/gut.2005.081745
	Analysis of the influence of OCTN1/2 variants within the IBD5 locus on disease susceptibility and growth indices in early onset inflammatory bowel disease R K Russell, H E Drummond, E R Nimmo, N H Anderson, C L Noble, D C Wilson, P M Gillett, P McGrogan, K Hassan, L T Weaver, W M Bisset, G Mahdi, and J Satsangi Gut 2006; 55: 1114-1123. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 9 February 2006. doi:10.1136/gut.2005.082107
	Phenotype at diagnosis predicts recurrence rates in Crohn’s disease F L Wolters, M G Russel, J Sijbrandij, T Ambergen, S Odes, L Riis, E Langholz, P Politi, A Qasim, I Koutroubakis, E Tsianos, S Vermeire, J Freitas, G van Zeijl, O Hoie, T Bernklev, M Beltrami, D Rodriguez, R W Stockbrügger, B Moum on behalf of the European Collaborative Study Group on Inflammatory Bowel Disease (EC-IBD) Gut 2006; 55: 1124-1130. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 16 December 2005. doi:10.1136/gut.2005.084061
	Fontolizumab, a humanised anti-interferon antibody, demonstrates safety and clinical activity in patients with moderate to severe Crohn’s disease D W Hommes, T L Mikhajlova, S Stoinov, D Stimac, B Vucelic, J Lonovics, M Zákuciová, G D’Haens, G Van Assche, S Ba, S Lee, and T Pearce Gut 2006; 55: 1131-1137. [Abstract] [Full text] [Competing interest statement] [PDF] [Request Permissions]   Published Online First: 28 February 2006. doi:10.1136/gut.2005.079392
	A dose escalating, placebo controlled, double blind, single dose and multidose, safety and tolerability study of fontolizumab, a humanised anti-interferon antibody, in patients with moderate to severe Crohn’s disease W Reinisch, D W Hommes, G Van Assche, J-F Colombel, J-P Gendre, B Oldenburg, A Teml, K Geboes, H Ding, L Zhang, M Tang, M Cheng, S J H van Deventer, P Rutgeerts, and T Pearce Gut 2006; 55: 1138-1144. [Abstract] [Full text] [Competing interest statement] [PDF] [Request Permissions]   Published Online First: 21 February 2006. doi:10.1136/gut.2005.079434

Colorectal cancer

	Does a negative screening colonoscopy ever need to be repeated? H Brenner, J Chang-Claude, C M Seiler, T Stürmer, and M Hoffmeister Gut 2006; 55: 1145-1150. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 9 February 2006. doi:10.1136/gut.2005.087130
	Sporadic adenoma in ulcerative colitis: endoscopic resection is an adequate treatment M Vieth, H Behrens, and M Stolte Gut 2006; 55: 1151-1155. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 19 January 2006. doi:10.1136/gut.2005.075531
	A recombinant anti-carcinoembryonic antigen immunoreceptor with combined CD3-CD28 signalling targets T cells from colorectal cancer patients against their tumour cells A Hombach, C Schlimper, E Sievers, S Frank, H H Schild, T Sauerbruch, I G H Schmidt-Wolf, and H Abken Gut 2006; 55: 1156-1164. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 27 September 2005. doi:10.1136/gut.2005.076208

Pancreatitis

	A selective COX-2 inhibitor suppresses chronic pancreatitis in an animal model (WBN/Kob rats): significant reduction of macrophage infiltration and fibrosis T Reding, D Bimmler, A Perren, L-K Sun, F Fortunato, F Storni, and R Graf Gut 2006; 55: 1165-1173. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 1 December 2005. doi:10.1136/gut.2005.077925

Liver disease

Overexpression of Bcl-2 by activated human hepatic stellate cells: resistance to apoptosis as a mechanism of progressive hepatic fibrogenesis in humans E Novo, F Marra, E Zamara, L Valfrè di Bonzo, L Monitillo, S Cannito, I Petrai, A Mazzocca, A Bonacchi, R S M De Franco, S Colombatto, R Autelli, M Pinzani, and M Parola Gut 2006; 55: 1174-1182. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 19 January 2006. doi:10.1136/gut.2005.082701

Hepatitis

	Higher clearance of hepatitis C virus infection in females compared with males I Bakr, C Rekacewicz, M El Hosseiny, S Ismail, M El Daly, S El-Kafrawy, G Esmat, M A Hamid, M K Mohamed, and A Fontanet Gut 2006; 55: 1183-1187. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 24 January 2006. doi:10.1136/gut.2005.078147
	Altered expression and activation of signal transducers and activators of transcription (STATs) in hepatitis C virus infection: in vivo and in vitro studies E Larrea, R Aldabe, E Molano, C M Fernandez-Rodriguez, A Ametzazurra, M P Civeira, and J Prieto Gut 2006; 55: 1188-1196. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 24 August 2005. doi:10.1136/gut.2005.070060

JournalScan

	JournalScan Gut 2006; 55: 1197. [Extract] [Full text] [PDF] [Request Permissions]

Recent advances in clinical practice

	Fertility and pregnancy in the patient with inflammatory bowel disease U Mahadevan Gut 2006; 55: 1198-1206. doi:10.1136/gut.2005.078097 [Extract] [Full text] [Competing interest statement] [PDF] [Request Permissions]

Letters

	Reduced microbial diversity in inflammatory bowel diseases S J Ott and S Schreiber Gut 2006; 55: 1207. [Extract] [Full text] [Competing interest statement] [PDF] [Request Permissions]
	Analysis of the c-kit gene in patients with slow transit constipation W-D Tong, B-H Liu, L-Y Zhang, and S-B Zhang Gut 2006; 55: 1207-1208. doi:10.1136/gut.2006.094953 [Extract] [Full text] [PDF] [Request Permissions]
	Does longitudinal muscle contraction of the oesophagus hold important secrets? N A Tipnis and R K Mittal Gut 2006; 55: 1208. [Extract] [Full text] [PDF] [Request Permissions]
	Duration of lamivudine prophylaxis in inactive hepatitis B virus carriers with haemato/oncological malignancies who receive chemotherapy R Idilman Gut 2006; 55: 1208-1209. [Extract] [Full text] [PDF] [Request Permissions]
	Treatment of local ischaemia: another promising approach for gastrointestinal complications of pelvic radiotherapy T Konishi, T Watanabe, and H Nagawa Gut 2006; 55: 1209. [Extract] [Full text] [PDF] [Request Permissions]
	A severe but reversible refractory sprue X Dray, F Joly, A Lavergne-Slove, X Treton, Y Bouhnik, and B Messing Gut 2006; 55: 1210-1211. doi:10.1136/gut.2005.089987 [Extract] [Full text] [PDF] [Request Permissions]
	Severe recurrent Crohn’s disease of ileocolonic anastomosis and antimicrobial (anti-mycobacterial) therapy T J Borody and L B Heifets Gut 2006; 55: 1211. [Extract] [Full text] [PDF] [Request Permissions]
	Complication rates of ablation therapies for hepatocellular carcinoma: a difficult comparison with an easy solution V Arienti and S Pretolani Gut 2006; 55: 1211. [Extract] [Full text] [PDF] [Request Permissions]
	Increased risk of NASH in patients carrying the C(–159)T polymorphism in the CD14 gene promoter region P Brun, I Castagliuolo, A R Floreani, A Buda, L Blasone, G Palù, and D Martines Gut 2006; 55: 1212. doi:10.1136/gut.2006.093336 [Extract] [Full text] [PDF] [Request Permissions]
	Lavage of a mucinous cystadenoma of the pancreas with povidone iodate E Gaia, P Salacone, and A Cataldi Gut 2006; 55: 1212-1213. doi:10.1136/gut.2006.095422 [Extract] [Full text] [PDF] [Request Permissions]
	BRAF mutation and gene methylation frequencies of colorectal tumours with microsatellite instability increase markedly with patient age B Iacopetta, W Q Li, F Grieu, A Ruszkiewicz, and K Kawakami Gut 2006; 55: 1213. doi:10.1136/gut.2006.095455 [Extract] [Full text] [PDF] [Request Permissions]
	[–215G>A; IVS3+2T>C] mutation in the SPINK1 gene causes exon 3 skipping and loss of the trypsin binding site K Kume, A Masamune, K Kikuta, and T Shimosegawa Gut 2006; 55: 1214. doi:10.1136/gut.2006.095752 [Extract] [Full text] [PDF] [Request Permissions]
	Neoadjuvant chemoradiation treatment impairs accuracy of MRI staging in rectal carcinoma J Jonas and R Bähr Gut 2006; 55: 1214-1215. doi:10.1136/gut.2006.095034 [Extract] [Full text] [PDF] [Request Permissions]

Book reviews

	Gastrointestinal Cancer H Wasan Gut 2006; 55: 1215-1216. doi:10.1136/gut.2005.078188 [Extract] [Full text] [PDF] [Request Permissions]