Leading articles

	Proton pump inhibitors and gastric neoplasia E J Kuipers Gut 2006; 55: 1217-1221. doi:10.1136/gut.2005.090514 [Abstract] [Full text] [PDF] [Request Permissions]

Digest

	Digest Robin Spiller and Alastair Watson Gut 2006; 55: 1217. [Extract] [Full text] [PDF] [Request Permissions]

Commentaries

	Ablating Barrett’s metaplastic epithelium: are the techniques ready for clinical use? J J G H M Bergman and P Fockens Gut 2006; 55: 1222-1223. doi:10.1136/gut.2006.092106 [Extract] [Full text] [PDF] [Request Permissions]
	Tacrolimus—finally! K R Herrlinger, K Fellermann, and E F Stange Gut 2006; 55: 1224-1225. doi:10.1136/gut.2006.093302 [Extract] [Full text] [PDF] [Request Permissions]
	Role of interleukin 6 in a murine model of Crohn’s ileitis: are cytokine/anticytokine strategies the future for IBD therapies? T T Pizarro, S A De La Rue, and F Cominelli Gut 2006; 55: 1226-1227. doi:10.1136/gut.2005.083121 [Extract] [Full text] [PDF] [Request Permissions]
	Human pancreatitis and the role of cathepsin B M M Lerch and W Halangk Gut 2006; 55: 1228-1230. doi:10.1136/gut.2006.092114 [Extract] [Full text] [PDF] [Request Permissions]
	Role of endothelin in systemic and portal resistance in cirrhosis P W Angus Gut 2006; 55: 1230-1232. doi:10.1136/gut.2005.088633 [Extract] [Full text] [PDF] [Request Permissions]

Barrett's oesophagus

	A randomised controlled trial of ablation of Barrett’s oesophagus with multipolar electrocoagulation versus argon plasma coagulation in combination with acid suppression: long term results P Sharma, S Wani, A P Weston, A Bansal, M Hall, S Mathur, A Prasad, and R E Sampliner Gut 2006; 55: 1233-1239. doi:10.1136/gut.2005.086777 [Abstract] [Full text] [PDF] [Request Permissions]

Gut immunology

	The gut–joint axis: cross reactive food antibodies in rheumatoid arthritis M Hvatum, L Kanerud, R Hällgren, and P Brandtzaeg Gut 2006; 55: 1240-1247. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 16 February 2006. doi:10.1136/gut.2005.076901

Inflammatory bowel disease

	Survival and cause specific mortality in patients with inflammatory bowel disease: a long term outcome study in Olmsted County, Minnesota, 1940–2004 T Jess, E V Loftus, Jr, W S Harmsen, A R Zinsmeister, W J Tremaine, L J Melton, III, P Munkholm, and W J Sandborn Gut 2006; 55: 1248-1254. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 19 January 2006. doi:10.1136/gut.2005.079350
	A randomised dose finding study of oral tacrolimus (FK506) therapy in refractory ulcerative colitis H Ogata, T Matsui, M Nakamura, M Iida, M Takazoe, Y Suzuki, and T Hibi Gut 2006; 55: 1255-1262. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 16 February 2006. doi:10.1136/gut.2005.081794
	STAT3 activation via interleukin 6 trans-signalling contributes to ileitis in SAMP1/Yit mice K Mitsuyama, S Matsumoto, S Rose-John, A Suzuki, T Hara, N Tomiyasu, K Handa, O Tsuruta, H Funabashi, J Scheller, A Toyonaga, and M Sata Gut 2006; 55: 1263-1269. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 8 May 2006. doi:10.1136/gut.2005.079343

Miscellanea

	Catastrophic lower gastrointestinal complications following spinal surgery E J Dean, M Shrotri, V Tagore, D White, and S Sarkar Gut 2006; 55: 1262. doi:10.1136/gut.2005.084707 [Extract] [Full text] [PDF] [Request Permissions]
	Recurrent gastrointestinal haemorrhage from the distal duodenum M H Holtmann, T Keller, P R Galle, and R Kiesslich Gut 2006; 55: 1275. doi:10.1136/gut.2005.084772 [Extract] [Full text] [PDF] [Request Permissions]
	Answer Gut 2006; 55: 1289. [Extract] [Full text] [PDF] [Request Permissions]
	Tracheal-oesophageal fistula in a patient with lung cancer Y S Guan and Y Liu Gut 2006; 55: 1295. doi:10.1136/gut.2005.084087 [Extract] [Full text] [PDF] [Request Permissions]
	Answer Gut 2006; 55: 1305. [Extract] [Full text] [PDF] [Request Permissions]
	Answer Gut 2006; 55: 1331. [Extract] [Full text] [PDF] [Request Permissions]
	An infrequent cause of gastrointestinal bleeding S Greco, G Maconi, C Penati, A Norsa, and G Bianchi Porro Gut 2006; 55: 1339. doi:10.1136/gut.2005.086157 [Extract] [Full text] [PDF] [Request Permissions]
	Answer Gut 2006; 55: 1359. [Extract] [Full text] [PDF] [Request Permissions]

Pancreatitis

	Association of cathepsin B gene polymorphisms with tropical calcific pancreatitis S Mahurkar, M M Idris, D N Reddy, S Bhaskar, G V Rao, V Thomas, L Singh, and G R Chandak Gut 2006; 55: 1270-1275. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 21 February 2006. doi:10.1136/gut.2005.087403

Liver fibrosis

	Hepatic stellate cells express synemin, a protein bridging intermediate filaments to focal adhesions N Uyama, L Zhao, E Van Rossen, Y Hirako, H Reynaert, D H Adams, Z Xue, Z Li, R Robson, M Pekny, and A Geerts Gut 2006; 55: 1276-1289. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 16 February 2006. doi:10.1136/gut.2005.078865

Liver disease

	Endothelin-1 contributes to maintenance of systemic but not portal haemodynamics in patients with early cirrhosis: a randomised controlled trial D Tripathi, G Therapondos, J W Ferguson, D E Newby, D J Webb, and P C Hayes Gut 2006; 55: 1290-1295. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 24 January 2006. doi:10.1136/gut.2005.077453
	Intrahepatic upregulation of RhoA and Rho-kinase signalling contributes to increased hepatic vascular resistance in rats with secondary biliary cirrhosis Q Zhou, M Hennenberg, J Trebicka, K Jochem, L Leifeld, E Biecker, T Sauerbruch, and J Heller Gut 2006; 55: 1296-1305. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 21 February 2006. doi:10.1136/gut.2005.081059
	Insulin-like growth factor I improves intestinal barrier function in cirrhotic rats V Lorenzo-Zúñiga, C M Rodríguez-Ortigosa, R Bartolí, M-L Martínez-Chantar, L Martínez-Peralta, A Pardo, I Ojanguren, J Quiroga, R Planas, and J Prieto Gut 2006; 55: 1306-1312. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 24 January 2006. doi:10.1136/gut.2005.079988
	Chitotriosidase gene expression in Kupffer cells from patients with non-alcoholic fatty liver disease L Malaguarnera, M Di Rosa, A M Zambito, N dell’Ombra, F Nicoletti, and M Malaguarnera Gut 2006; 55: 1313-1320. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 6 July 2006. doi:10.1136/gut.2005.075697
	Cholesterol dependent downregulation of mouse and human apical sodium dependent bile acid transporter (ASBT) gene expression: molecular mechanism and physiological consequences C Thomas, J-F Landrier, D Gaillard, J Grober, M-C Monnot, A Athias, and P Besnard Gut 2006; 55: 1321-1331. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 16 February 2006. doi:10.1136/gut.2005.085555

Hepatitis

	Cost effectiveness of interferon or peginterferon with ribavirin for histologically mild chronic hepatitis C R Grieve, J Roberts, M Wright, M Sweeting, D DeAngelis, W Rosenberg, M Bassendine, J Main, and H Thomas Gut 2006; 55: 1332-1338. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 30 June 2005. doi:10.1136/gut.2005.064774

JournalScan

	JournalScan Gut 2006; 55: 1340. [Extract] [Full text] [PDF] [Request Permissions]

Recent advances in basic science

	PPAR as a new therapeutic target in inflammatory bowel diseases L Dubuquoy, C Rousseaux, X Thuru, L Peyrin-Biroulet, O Romano, P Chavatte, M Chamaillard, and P Desreumaux Gut 2006; 55: 1341-1349. doi:10.1136/gut.2006.093484 [Extract] [Full text] [PDF] [Request Permissions]

Recent advances in clinical practice

	Treating viral hepatitis C: efficacy, side effects, and complications M P Manns, H Wedemeyer, and M Cornberg Gut 2006; 55: 1350-1359. doi:10.1136/gut.2005.076646 [Extract] [Full text] [Conflict of Interest] [PDF] [Request Permissions]

Letters

	Helicobacter pylori outer membrane proteins and gastric inflammation • Author’s reply A Dossumbekova, C Prinz, M Gerhard, L Brenner, S Backert, J G Kusters, R M Schmid, R Rad, and Y Yamaoka Gut 2006; 55: 1360-1361. [Extract] [Full text] [PDF] [Request Permissions]
	Severe self limiting sclerosing cholangitis after pancreaticoduodenectomy due to autoimmune pancreatitis A Schmassmann, P Zehnder, J-O Gebbers, and A Wildisen Gut 2006; 55: 1361-1362. doi:10.1136/gut.2006.097386 [Extract] [Full text] [PDF] [Request Permissions]
	Disappointing results of combination therapy for HCV? T Dudley, K O’Donnell, G Haydon, and D Mutimer Gut 2006; 55: 1362-1363. doi:10.1136/gut.2006.094292 [Extract] [Full text] [PDF] [Request Permissions]
	Leukotriene receptor antagonists as potential steroid sparing agents in a patient with serosal eosinophilic gastroenteritis M C Urek, M Kujundzic, M Banic, R Urek, T S Veic, and D Kardum Gut 2006; 55: 1363-1364. doi:10.1136/gut.2006.099465 [Extract] [Full text] [PDF] [Request Permissions]
	Prevention of abortion by ciclosporin treatment of fulminant ulcerative colitis during pregnancy S Angelberger, W Reinisch, and C Dejaco Gut 2006; 55: 1364-1365. [Extract] [Full text] [PDF] [Request Permissions]
	Effect of MRCP introduction on ERCP practice: are there implications for service and training? J T Jenkins, G Glass, S Ballantyne, and G M Fullarton Gut 2006; 55: 1365-1366. doi:10.1136/gut.2006.097055 [Extract] [Full text] [PDF] [Request Permissions]
	A novel method to determine small intestinal barrier function in human neonates in vivo M W Schaart, H Schierbeek, A C J M de Bruijn, D Tibboel, J B van Goudoever, and I B Renes Gut 2006; 55: 1366-1367. doi:10.1136/gut.2006.096016 [Extract] [Full text] [PDF] [Request Permissions]
	Genetic association of Fc receptor-like 3 polymorphisms with autoimmune pancreatitis in Japanese patients T Umemura, M Ota, H Hamano, Y Katsuyama, K Kiyosawa, and S Kawa Gut 2006; 55: 1367-1368. doi:10.1136/gut.2006.095059 [Extract] [Full text] [PDF] [Request Permissions]
	Extensive intestinal ischaemic necrosis in Wegener’s granulomatosis F M Shaikh, C B Sabu, T H Peirce, and S A Naqvi Gut 2006; 55: 1368-1369. doi:10.1136/gut.2006.096768 [Extract] [Full text] [PDF] [Request Permissions]
	Elevated CD4+/CD25+ T cell frequency and function during acute hepatitis C presage chronic evolution A Perrella, L Vitiello, L Atripaldi, P Conti, C Sbreglia, S Altamura, T Patarino, R Vela, G Morelli, P Bellopede, C Alone, L Racioppi, and O Perrella Gut 2006; 55: 1370-1371. doi:10.1136/gut.2006.099887 [Extract] [Full text] [PDF] [Request Permissions]
	Thalidomide in refractory haemorrhagic radiation induced proctitis M E Craanen, B van Triest, R H M Verheijen, and C J J Mulder Gut 2006; 55: 1371-1372. doi:10.1136/gut.2006.099416 [Extract] [Full text] [PDF] [Request Permissions]
	A case of rheumatoid arthritis with protein losing enteropathy induced by multiple diaphragmatic strictures of the small intestine: successful treatment by bougieing under double-balloon enteroscopy Y Kamata, M Iwamoto, H Nara, T Kamimura, N Takayashiki, H Yamamoto, K Sugano, T Yoshio, H Okazaki, and S Minota Gut 2006; 55: 1372. doi:10.1136/gut.2006.100446 [Extract] [Full text] [PDF] [Request Permissions]