Leading articles

	The IL23 axis plays a key role in the pathogenesis of IBD Dermot McGovern and Fiona Powrie Gut 2007; 56: 1333-1336. doi:10.1136/gut.2006.115402 [Abstract] [Full text] [PDF] [Request Permissions]

Digest

	Digest Robin Spiller and Emad M El-Omar Gut 2007; 56: 1333. [Extract] [Full text] [PDF] [Request Permissions]

Miscellaneous

	Multiple liver lesions in a smoker J Sharkey, K R Palmer, I D R Arnott, and S Glancy Gut 2007; 56: 1336. doi:10.1136/gut.2006.104893 [Extract] [Full text] [PDF] [Request Permissions]
	A cause of cholestatic jaundice P G Wheeler, A Atrey, A Healey, K M Taylor, and L R Jiao Gut 2007; 56: 1346. doi:10.1136/gut.2006.107029 [Extract] [Full text] [PDF] [Request Permissions]
	EDITOR’S QUIZ: GI SNAPSHOT Gut 2007; 56: 1352. [Extract] [Full text] [PDF] [Request Permissions]
	A huge intra-abdominal mass in a young man T Tsujino, H Kogure, N Sasahira, H Isayama, M Tada, T Kawabe, M Omata, M Akahane, K Sano, and M Makuuchi Gut 2007; 56: 1372. doi:10.1136/gut.2006.102814 [Extract] [Full text] [PDF] [Request Permissions]
	EDITOR’S QUIZ: GI SNAPSHOT Gut 2007; 56: 1386. [Extract] [Full text] [PDF] [Request Permissions]
	EDITOR’S QUIZ: GI SNAPSHOT Gut 2007; 56: 1393. doi:10.1136/gut.2006.102814a [Extract] [Full text] [PDF] [Request Permissions]
	Jaundice in a chronic hepatitis B carrier R Noun, S Zeidan, C Ghorra, S Slaba, L Menassa-Moussa, and R Sayegh Gut 2007; 56: 1409. doi:10.1136/gut.2006.103887 [Extract] [Full text] [PDF] [Request Permissions]
	EDITOR’S QUIZ: GI SNAPSHOT Gut 2007; 56: 1425. doi:10.1136/gut.2006.103887a [Extract] [Full text] [PDF] [Request Permissions]

Commentaries

	2 ligand: a new, smart pill for visceral pain in patients with hypersensitive irritable bowel syndrome? Michael Camilleri Gut 2007; 56: 1337-1338. doi:10.1136/gut.2007.127514 [Extract] [Full text] [PDF] [Request Permissions]
	Latent coeliac disease or coeliac disease beyond villous atrophy? Katri Kaukinen, Pekka Collin, and Markku Mäki Gut 2007; 56: 1339-1340. doi:10.1136/gut.2006.113084 [Extract] [Full text] [PDF] [Request Permissions]
	Giving APCmin tumours a SPARC Alex Gregorieff and Hans Clevers Gut 2007; 56: 1341-1343. [Extract] [Full text] [PDF] [Request Permissions]   Published Online First: 19 April 2007. doi:10.1136/gut.2007.122135
	What is the role of iFOBT in screening for colorectal cancer? David F Ransohoff Gut 2007; 56: 1343-1344. doi:10.1136/gut.2007.124107 [Extract] [Full text] [PDF] [Request Permissions]
	Antioxidants in acute pancreatitis C D Johnson Gut 2007; 56: 1344-1345. doi:10.1136/gut.2007.122101 [Extract] [Full text] [PDF] [Request Permissions]

Oesophagus

	Intraluminal acid induces oesophageal shortening via capsaicin-sensitive neurokinin neurons William G Paterson, David V Miller, Neil Dilworth, Joseph B Assini, Sandra Lourenssen, and Michael G Blennerhassett Gut 2007; 56: 1347-1352. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 24 May 2007. doi:10.1136/gut.2006.115881

Stomach

	The sequential therapy regimen for Helicobacter pylori eradication: a pooled-data analysis Angelo Zullo, Vincenzo De Francesco, Cesare Hassan, Sergio Morini, and Dino Vaira Gut 2007; 56: 1353-1357. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 12 June 2007. doi:10.1136/gut.2007.125658
	Clinical impact of genetic aberrations in gastric MALT lymphoma: a comprehensive analysis using interphase fluorescence in situ hybridisation Shotaro Nakamura, Hongtao Ye, Chris M Bacon, Alison Goatly, Hongxiang Liu, Alison H Banham, Roland Ventura, Takayuki Matsumoto, Mitsuo Iida, Yutaka Ohji, Takashi Yao, Masazumi Tsuneyoshi, and Ming-Qing Du Gut 2007; 56: 1358-1363. [Abstract] [Full text] [web only table] [PDF] [Request Permissions]   Published Online First: 24 May 2007. doi:10.1136/gut.2007.123729
	Endoscopic clipping versus injection and thermo-coagulation in the treatment of non-variceal upper gastrointestinal bleeding: a meta-analysis Joseph J Y Sung, Kelvin K F Tsoi, Larry H Lai, Justin C Y Wu, and James Y W Lau Gut 2007; 56: 1364-1373. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 12 June 2007. doi:10.1136/gut.2007.123976

Coeliac disease

	Survival in refractory coeliac disease and enteropathy-associated T-cell lymphoma: retrospective evaluation of single-centre experience A Al-toma, W H M Verbeek, M Hadithi, B M E von Blomberg, and C J J Mulder Gut 2007; 56: 1373-1378. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 30 April 2007. doi:10.1136/gut.2006.114512
	Long-term follow-up of 61 coeliac patients diagnosed in childhood: evolution toward latency is possible on a normal diet Tamara Matysiak-Budnik, Georgia Malamut, Natacha Patey-Mariaud de Serre, Etienne Grosdidier, Sylvie Seguier, Nicole Brousse, Sophie Caillat-Zucman, Nadine Cerf-Bensussan, Jacques Schmitz, and Christophe Cellier Gut 2007; 56: 1379-1386. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 15 February 2007. doi:10.1136/gut.2006.100511

Inflammatory bowel disease

	The risk of developing Crohn’s disease after an appendectomy: a population-based cohort study in Sweden and Denmark Gilaad G Kaplan, Bo V Pedersen, Roland E Andersson, Bruce E Sands, Joshua Korzenik, and Morten Frisch Gut 2007; 56: 1387-1392. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 9 May 2007. doi:10.1136/gut.2007.121467
	New serological markers in inflammatory bowel disease are associated with complicated disease behaviour Marc Ferrante, Liesbet Henckaerts, Marie Joossens, Marie Pierik, Sofie Joossens, Nir Dotan, Gary L Norman, Rom T Altstock, Kristel Van Steen, Paul Rutgeerts, Gert Van Assche, and Séverine Vermeire Gut 2007; 56: 1394-1403. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 24 April 2007. doi:10.1136/gut.2006.108043
	Nodular regenerative hyperplasia in patients with inflammatory bowel disease treated with azathioprine G Vernier-Massouille, J Cosnes, M Lemann, P Marteau, W Reinisch, D Laharie, G Cadiot, Y Bouhnik, M De Vos, A Boureille, B Duclos, P Seksik, J-Y Mary, and J-F Colombel Gut 2007; 56: 1404-1409. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 15 May 2007. doi:10.1136/gut.2006.114363

Colorectal cancer

	Deficiency of SPARC suppresses intestinal tumorigenesis in APCMin/+ mice Owen J Sansom, Fiona C Mansergh, Martin J Evans, Julie A Wilkins, and Alan R Clarke Gut 2007; 56: 1410-1414. [Abstract] [Full text] [web only appendices] [PDF] [Request Permissions]   Published Online First: 13 February 2007. doi:10.1136/gut.2006.116921
	Evaluation of a card collection-based faecal immunochemical test in screening for colorectal cancer using a two-tier reflex approach Callum G Fraser, Catriona M Mathew, N Ashley G Mowat, John A Wilson, Francis A Carey, and Robert J C Steele Gut 2007; 56: 1415-1418. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 19 February 2007. doi:10.1136/gut.2007.119651
	Who to treat with adjuvant therapy in Dukes B/stage II colorectal cancer? The need for high quality pathology Eva J A Morris, Nicola J Maughan, David Forman, and Philip Quirke Gut 2007; 56: 1419-1425. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 9 May 2007. doi:10.1136/gut.2006.116830
	The angiogenic switch occurs at the adenoma stage of the adenoma–carcinoma sequence in colorectal cancer Carolyn A Staton, Andrew S A Chetwood, Iain C Cameron, Simon S Cross, Nicola J Brown, and Malcolm W R Reed Gut 2007; 56: 1426-1432. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 12 June 2007. doi:10.1136/gut.2007.125286

Pancreas

	Missense mutations in pancreatic secretory trypsin inhibitor (SPINK1) cause intracellular retention and degradation Orsolya Király, Thomas Wartmann, and Miklós Sahin-Tóth Gut 2007; 56: 1433-1438. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 24 May 2007. doi:10.1136/gut.2006.115725
	Randomised, double blind, placebo controlled trial of intravenous antioxidant (n-acetylcysteine, selenium, vitamin C) therapy in severe acute pancreatitis Ajith K Siriwardena, James M Mason, Srinivasan Balachandra, Anil Bagul, Simon Galloway, Laura Formela, Jonathan G Hardman, and Saurabh Jamdar Gut 2007; 56: 1439-1444. [Abstract] [Full text] [web only appendix] [PDF] [Request Permissions]   Published Online First: 13 March 2007. doi:10.1136/gut.2006.115873

Hepatitis

	Periportal and sinusoidal liver dendritic cells suppressing T helper type 1-mediated hepatitis Tomohiro Watanabe, Hiroaki Katsukura, Tsutomu Chiba, Toru Kita, and Yoshio Wakatsuki Gut 2007; 56: 1445-1451. doi:10.1136/gut.2007.121251 [Abstract] [Full text] [PDF] [Request Permissions]

JournalScan

	JournalScan Gut 2007; 56: 1452. [Extract] [Full text] [PDF] [Request Permissions]

Recent advances in basic science

	Serrated pathway colorectal cancer in the population: genetic consideration Joanne Young, Mark Jenkins, Susan Parry, Bruce Young, Derek Nancarrow, Dallas English, Graham Giles, and Jeremy Jass Gut 2007; 56: 1453-1459. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 12 June 2007. doi:10.1136/gut.2007.126870

Gut tutorial

	A patient with dysphagia J Y Kang Gut 2007; 56: 1459. doi:10.1136/gut.2007.132506 [Extract] [Full text] [PDF] [Request Permissions]   BMJ Learning: Take this module on BMJ Learning

Recent advances in clinical practice

Advances in counselling and surveillance of patients at risk for pancreatic cancer Randall E Brand, Markus M Lerch, Wendy S Rubinstein, John P Neoptolemos, David C Whitcomb, Ralph H Hruban, Teresa A Brentnall, Henry T Lynch, Marcia I Canto Participants of the Fourth International Symposium of Inherited Diseases of the Pancreas Gut 2007; 56: 1460-1469. doi:10.1136/gut.2006.108456 [Abstract] [Full text] [PDF] [Request Permissions]

Letters

	Occult hepatitis B virus infection in patients with non-Hodgkin lymphoma: the need for early diagnosis in anti-Hbc positive patients E Persico, A De Renzo, V La Mura, S Bruno, M Masarone, R Torella, and M Persico Gut 2007; 56: 1470-1471. doi:10.1136/gut.2007.128777 [Extract] [Full text] [PDF] [Request Permissions]
	IgG4 associated autoimmune hepatitis: a differential diagnosis for classical autoimmune hepatitis T Umemura, Y Zen, H Hamano, T Ichijo, S Kawa, Y Nakanuma, and K Kiyosawa Gut 2007; 56: 1471-1472. [Extract] [Full text] [PDF] [Request Permissions]   Published Online First: 15 May 2007. doi:10.1136/gut.2007.122283
	The morphine–prostigmine provocation (Nardi) test for sphincter of Oddi dysfunction: results in healthy volunteers and in patients before and after transduodenal sphincteroplasty and transampullary septectomy D N Lobo, A S Takhar, A Thaper, M G Dube, and B J Rowlands Gut 2007; 56: 1472-1473. doi:10.1136/gut.2007.126375 [Extract] [Full text] [PDF] [Request Permissions]
	Urine based detection of intestinal mucosal cell damage in neonates with suspected necrotising enterocolitis J P M Derikx, N J Evennett, P L J Degraeuwe, T L Mulder, A A van Bijnen, L W E van Heurn, W A Buurman, and E Heineman Gut 2007; 56: 1473-1475. doi:10.1136/gut.2007.128934 [Extract] [Full text] [PDF] [Request Permissions]
	Peutz–Jeghers syndrome polyps are polyclonal with expanded progenitor cell compartment W W J de Leng, M Jansen, J J Keller, M de Gijsel, A N A Milne, F H M Morsink, M A J Weterman, C A Iacobuzio-Donahue, H C Clevers, F M Giardiello, and G J A Offerhaus Gut 2007; 56: 1475-1476. doi:10.1136/gut.2007.128132 [Extract] [Full text] [PDF] [Request Permissions]
	Lymphogranuloma venereum proctocolitis: mucosal T cell immunity of the rectum associated with chlamydial clearance and clinical recovery C van Nieuwkoop, J Gooskens, V T H B M Smit, E C J Claas, R A van Hogezand, A C M Kroes, and F P Kroon Gut 2007; 56: 1476-1477. doi:10.1136/gut.2007.128264 [Extract] [Full text] [PDF] [Request Permissions]
	Treatment of an atazanivir associated grade 4 hyperbilirubinaemia with efavirenz O Kummer, E Mossdorf, M Battegay, L Elzi, M Bodmer, S Krähenbühl, and M Haschke Gut 2007; 56: 1477-1478. doi:10.1136/gut.2007.126144 [Extract] [Full text] [PDF] [Request Permissions]
	Iron deficiency anaemia and perianastomotic ulceration as a late complication of ileal resection in infancy P Abdullannan and J W L Puntis Gut 2007; 56: 1478-1479. [Extract] [Full text] [PDF] [Request Permissions]
	Irritable bowel syndrome and negative appendectomy F Fleming and P Grace Gut 2007; 56: 1479. [Extract] [Full text] [PDF] [Request Permissions]
	Chemotherapy for mantle cell lymphoma • Authors’ reply R Sinharay, T Watanabe, H Hirono, K Hasegawa, K Soga, K Shibasaki, and Y Endo Gut 2007; 56: 1479-1480. [Extract] [Full text] [PDF] [Request Permissions]
	Does hyperhomocysteinaemia contribute to gastric carcinogenesis in Helicobacter pylori infected patients? • Author’s reply L Peyrin-Biroulet, Jean-Louis Guéant, A M C Rocha, G A Rocha, M C A Marino, and D M M Queiroz Gut 2007; 56: 1480-1481. [Extract] [Full text] [PDF] [Request Permissions]
	Biofilms in the normal human large bowel: fact rather than fiction R Randal Bollinger, Andrew S Barbas, Errol L Bush, Shu S Lin, and William Parker Gut 2007; 56: 1481-1482. [Extract] [Full text] [PDF] [Request Permissions]
	Pregabalin decreases visceral pain and prevents spinal neuronal activation in rats M Million, L Wang, D W Adelson, F Roman, L Diop, and Y Taché Gut 2007; 56: 1482-1484. doi:10.1136/gut.2007.129304 [Extract] [Full text] [PDF] [Request Permissions]
	Single aetiology and dual associations of cardiac cancer • Authors’ reply Johannes Lenglinger, Margit Eisler, Martin Riegler, Svein Hansen, Stein Emil Vollset, Mohammad H Derakhshan, and Kenneth E L McColl Gut 2007; 56: 1484-1485. [Extract] [Full text] [PDF] [Request Permissions]
	Relapse after treatment with peginterferon -2b alone or in combination with lamivudine in HBeAg positive chronic hepatitis B H J Flink, E H C J Buster, I Merican, F Nevens, G Kitis, J Cianciara, R A de Vries, B E Hansen, S W Schalm, and H L A Janssen Gut 2007; 56: 1485-1486. doi:10.1136/gut.2007.125633 [Extract] [Full text] [PDF] [Request Permissions]

Book reviews

	Clinical gastroenterology and hepatology John de Caestecker Gut 2007; 56: 1486-1487. doi:10.1136/gut.2007.121491 [Extract] [Full text] [PDF] [Request Permissions]
	The clinician’s guide to acid/peptic disorders and motility disorders of the gastrointestinal tract Emad M El-Omar Gut 2007; 56: 1487. doi:10.1136/gut.2007.121418 [Extract] [Full text] [PDF] [Request Permissions]
	Clinical nutrition in gastrointestinal disease Julian R F Walters Gut 2007; 56: 1487-1488. doi:10.1136/gut.2007.121566 [Extract] [Full text] [PDF] [Request Permissions]
	Immunology and diseases of the gut Allan M Mowat Gut 2007; 56: 1488. doi:10.1136/gut.2007.124156 [Extract] [Full text] [PDF] [Request Permissions]