Leading articles

	Role of BRCA1 and BRCA2 mutations in pancreatic cancer Julia B Greer and David C Whitcomb Gut 2007; 56: 601-605. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 14 September 2006. doi:10.1136/gut.2006.101220

Digest

	Digest Robin Spiller and Emad El-Omar Gut 2007; 56: 601. [Extract] [Full text] [PDF] [Request Permissions]

Miscellaneous

	An unsuspected cause of chronic diarrhoea Salvatore Greco, Giovanni Maconi, Marco Lazzaroni, Luca Pastore, and Gabriele Bianchi Porro Gut 2007; 56: 605. doi:10.1136/gut.2006.095224 [Extract] [Full text] [PDF] [Request Permissions]
	An acute left-sided hydrothorax Hsien-Ling Chou, Shy-Shin Chang, and Chieng-Chang Lee Gut 2007; 56: 644. doi:10.1136/gut.2006.096123 [Extract] [Full text] [PDF] [Request Permissions]
	EDITOR’S QUIZ: GI SNAPSHOT Gut 2007; 56: 668. doi:10.1136/gut.2006.095224a [Extract] [Full text] [PDF] [Request Permissions]
	Familial liver disease Y Reddy, Z Twaij, and P D Mullins Gut 2007; 56: 676. doi:10.1136/gut.2006.097402 [Extract] [Full text] [PDF] [Request Permissions]
	EDITOR’S QUIZ: GI SNAPSHOT Gut 2007; 56: 698. doi:10.1136/gut.2006.096123a [Extract] [Full text] [PDF] [Request Permissions]
	EDITOR’S QUIZ: GI SNAPSHOT Gut 2007; 56: 732. doi:10.1136/gut.2006.097402a [Extract] [Full text] [PDF] [Request Permissions]

Commentaries

	Pathogenesis of gastrinomas associated with multiple endocrine neoplasia type 1 D M Pritchard Gut 2007; 56: 606-607. doi:10.1136/gut.2006.113985 [Extract] [Full text] [PDF] [Request Permissions]
	Avoiding unnecessary surgery in irritable bowel syndrome George F Longstreth Gut 2007; 56: 608-610. doi:10.1136/gut.2006.115006 [Extract] [Full text] [PDF] [Request Permissions]
	The role of Escherichia coli in inflammatory bowel disease Jonathan M Rhodes Gut 2007; 56: 610-612. doi:10.1136/gut.2006.111872 [Extract] [Full text] [PDF] [Request Permissions]
	Iron, haemochromatosis and thalassaemia as risk factors for fibrosis in hepatitis C virus infection Mark Thursz Gut 2007; 56: 613-614. doi:10.1136/gut.2006.113076 [Extract] [Full text] [PDF] [Request Permissions]

Oesophagus

	Prevalence of oesophageal eosinophils and eosinophilic oesophagitis in adults: the population-based Kalixanda study Jukka Ronkainen, Nicholas J Talley, Pertti Aro, Tom Storskrubb, Sven-Erik Johansson, Tore Lind, Elisabeth Bolling-Sternevald, Michael Vieth, Manfred Stolte, Marjorie M Walker, and Lars Agréus Gut 2007; 56: 615-620. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 29 November 2006. doi:10.1136/gut.2006.107714
	A critical role of serum response factor in myofibroblast differentiation during experimental oesophageal ulcer healing in rats Jianyuan Chai, Manith Norng, Andrzej S Tarnawski, and Justine Chow Gut 2007; 56: 621-630. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 26 October 2006. doi:10.1136/gut.2006.106674

Stomach and duodenum

	Gastritis staging in clinical practice: the OLGA staging system Massimo Rugge, Alberto Meggio, Gianmaria Pennelli, Francesco Piscioli, Luciano Giacomelli, Giovanni De Pretis, and David Y Graham Gut 2007; 56: 631-636. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 1 December 2006. doi:10.1136/gut.2006.106666
	Allelic deletion of the MEN1 gene in duodenal gastrin and somatostatin cell neoplasms and their precursor lesions M Anlauf, A Perren, T Henopp, T Rudolf, N Garbrecht, A Schmitt, A Raffel, O Gimm, E Weihe, W T Knoefel, H Dralle, Ph U Heitz, P Komminoth, and G Klöppel Gut 2007; 56: 637-644. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 29 November 2006. doi:10.1136/gut.2006.108910

Small intestine

	p53 independent induction of PUMA mediates intestinal apoptosis in response to ischaemia–reperfusion Bin Wu, Wei Qiu, Peng Wang, Hui Yu, Tao Cheng, Gerard P Zambetti, Lin Zhang, and Jian Yu Gut 2007; 56: 645-654. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 24 November 2006. doi:10.1136/gut.2006.101683

Irritable bowel syndrome

	Irritable bowel syndrome and negative appendectomy: a prospective multivariable investigation Ching-Liang Lu, Chun-Chu Liu, Jong-Ling Fuh, Pei-Yi Liu, Chew-Wun Wu, Full-Young Chang, and Shou-Dong Lee Gut 2007; 56: 655-660. doi:10.1136/gut.2006.112672 [Abstract] [Full text] [PDF] [Request Permissions]

Intestinal microflora and immunity

Gut microbiota composition and development of atopic manifestations in infancy: the KOALA Birth Cohort Study John Penders, Carel Thijs, Piet A van den Brandt, Ischa Kummeling, Bianca Snijders, Foekje Stelma, Hanne Adams, Ronald van Ree, and Ellen E Stobberingh Gut 2007; 56: 661-667. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 17 October 2006. doi:10.1136/gut.2006.100164

Inflammatory bowel disease

	High prevalence of Escherichia coli belonging to the B2+D phylogenetic group in inflammatory bowel disease Roman Kotlowski, Charles N Bernstein, Shadi Sepehri, and Denis O Krause Gut 2007; 56: 669-675. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 6 October 2006. doi:10.1136/gut.2006.099796

Colorectal cancer

	Option appraisal of population-based colorectal cancer screening programmes in England Paul Tappenden, James Chilcott, Simon Eggington, Hannah Sakai, Jonathon Karnon, and Julietta Patnick Gut 2007; 56: 677-684. [Abstract] [Full text] [web only appendix] [PDF] [Request Permissions]   Published Online First: 1 December 2006. doi:10.1136/gut.2006.095109

Pancreas

Suppression of transforming growth factor ß signalling aborts caerulein induced pancreatitis and eliminates restricted stimulation at high caerulein concentrations Stefan Wildi, Jörg Kleeff, Julia Mayerle, Arthur Zimmermann, Erwin P Böttinger, Lalage Wakefield, Markus W Büchler, Helmut Friess, and Murray Korc Gut 2007; 56: 685-692. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 29 November 2006. doi:10.1136/gut.2006.105833

Hepatitis

	Heterozygous ß-globin gene mutations as a risk factor for iron accumulation and liver fibrosis in chronic hepatitis C Massimo Sartori, Silvano Andorno, Michela Pagliarulo, Cristina Rigamonti, Cristina Bozzola, Patrizia Pergolini, Roberta Rolla, Anna Suno, Renzo Boldorini, Giorgio Bellomo, and Emanuele Albano Gut 2007; 56: 693-698. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 29 November 2006. doi:10.1136/gut.2006.106641
	Predicting response to peginterferon -2a, lamivudine and the two combined for HBeAg-negative chronic hepatitis B F Bonino, P Marcellin, G K K Lau, S Hadziyannis, R Jin, T Piratvisuth, G Germanidis, C Yurdaydin, M Diago, S Gurel, M-Y Lai, M R Brunetto, P Farci, M Popescu, P McCloud for the Peginterferon Alfa-2a HBeAg-Negative Chronic Hepatitis B Study Group Gut 2007; 56: 699-705. [Abstract] [Full text] [conflict statement] [PDF] [Request Permissions]   Published Online First: 24 November 2006. doi:10.1136/gut.2005.089722

Liver fibrosis

	Adenovirus-mediated expression of BMP-7 suppresses the development of liver fibrosis in rats Kohji Kinoshita, Yuji Iimuro, Kohji Otogawa, Shizuya Saika, Yutaka Inagaki, Yuji Nakajima, Norifumi Kawada, Jiro Fujimoto, Scott L Friedman, and Kazuo Ikeda Gut 2007; 56: 706-714. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 24 November 2006. doi:10.1136/gut.2006.092460

JournalScan

	JournalScan Gut 2007; 56: 715. [Extract] [Full text] [PDF] [Request Permissions]

Recent advances in basic science

	Bone marrow stem cells and liver disease Y N Kallis, M R Alison, and S J Forbes Gut 2007; 56: 716-724. [Extract] [Full text] [PDF] [Request Permissions]   Published Online First: 4 December 2006. doi:10.1136/gut.2006.098442

Recent advances in clinical practice

	Risks and benefits of biologic therapy for inflammatory bowel diseases Geert D’Haens Gut 2007; 56: 725-732. doi:10.1136/gut.2006.103564 [Extract] [Full text] [PDF] [Request Permissions]

Letters

	The role of the selective serotonin reuptake inhibitor citalopram in irritable bowel syndrome • Authors’ response L A S van Kerkhoven, R J F Laheij, J B M J Jansen, Lukas Van Oudenhove, and Jan Tack Gut 2007; 56: 733. [Extract] [Full text] [PDF] [Request Permissions]
	Mechanical lithotripsy for Bouveret’s syndrome • Authors’ response Muhammad Afzal, Debabrata Ghosh, Timothy Leigh, K-K Yau, Wing-Tai Siu, and Micheal Ka-Wah Li Gut 2007; 56: 733-734. doi:10.1136/gut.2006.111591 [Extract] [Full text] [PDF] [Request Permissions]
	Bevacizumab and postponed suture leakages after surgery for ulcerative colitis and rectal cancer Antoine Adenis, Luc Vanseymortier, David Foissey, and Jean-Frédéric Colombel Gut 2007; 56: 734. doi:10.1136/gut.2006.112524 [Extract] [Full text] [PDF] [Request Permissions]
	Fertility and ileal pouch-anal anastomosis • Authors’ response Timothy W Eglinton, Akbar K Waljee, Jennifer F Waljee, Arden M Morris, and Peter D R Higgins Gut 2007; 56: 735. doi:10.1136/gut.2006.114322 [Extract] [Full text] [PDF] [Request Permissions]
	Transplantation for alcoholic liver disease Andrea De Gottardi and Jérôme Dumortier Gut 2007; 56: 735-736. [Extract] [Full text] [PDF] [Request Permissions]   Published Online First: 5 December 2006. doi:10.1136/gut.2006.115022
	Role of RET and ko=PHOX2B gene polymorphisms in risk of Hirschsprung’s disease in Chinese population Xiaoping Miao, Maria-Mercè Garcia-Barceló, Man-ting So, Thomas Yuk-Yu Leon, Danny Ko-chun Lau, Ting-Ting Liu, Edwin Kin-Wai Chan, Lawrence Chuen-Leung Lan, Kenneth Kak-yuen Wong, Vincent Chi-hang Lui, and Paul Kwong-hang Tam Gut 2007; 56: 736. doi:10.1136/gut.2006.116145 [Extract] [Full text] [PDF] [Request Permissions]
	The incidence and risks of liver biopsy in non-cirrhotic patients: An evaluation of 3806 biopsies Jee-Fu Huang, Ming-Yen Hsieh, Chia-Yen Dai, Nai-Jen Hou, Li-Po Lee, Zu-Yau Lin, Shinn-Chern Chen, Liang-Yen Wang, Ming-Yuh Hsieh, Wen-Yu Chang, Ming-Lung Yu, and Wan-Long Chuang Gut 2007; 56: 736-737. doi:10.1136/gut.2006.115410 [Extract] [Full text] [PDF] [Request Permissions]
	The role of gender on clearance of hepatitis C virus: a different story in an area endemic for hepatitis B and C Chia-Yen Dai, Jee-Fu Huang, Ming-Yen Hsieh, Li-Po Lee, Chi-Kung Ho, Wan-Long Chuang, and Ming-Lung Yu Gut 2007; 56: 737-738. doi:10.1136/gut.2006.116384 [Extract] [Full text] [PDF] [Request Permissions]
	Relation between incidence of hepatic carcinogenesis and integration value of alanine aminotransferase in patients with hepatitis C virus infection Takashi Kumada, Hidenori Toyoda, Seiki Kiriyama, Yasuhiro Sone, Makoto Tanikawa, Yasuhiro Hisanaga, Akira Kanamori, Junji Kondo, Takahiro Yamauchi, and Satoshi Nakano Gut 2007; 56: 738-739. doi:10.1136/gut.2006.118455 [Extract] [Full text] [PDF] [Request Permissions]

Book reviews

	Upper Gastrointestinal Surgery N Theodorou Gut 2007; 56: 739-740. doi:10.1136/gut.2005.078204 [Extract] [Full text] [PDF] [Request Permissions]
	Challenges in Inflammatory Bowel Disease, 2nd Edition James Lindsay Gut 2007; 56: 740. doi:10.1136/gut.2006.106617 [Extract] [Full text] [PDF] [Request Permissions]
	Clinical Dilemmas in Inflammatory Bowel Disease D P Jewell Gut 2007; 56: 740. doi:10.1136/gut.2006.106609 [Extract] [Full text] [PDF] [Request Permissions]