Leading articles

	Stress-related changes in oesophageal permeability: filling the gaps of GORD? Johan D Söderholm Gut 2007; 56: 1177-1180. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 20 April 2007. doi:10.1136/gut.2007.120691

Digest

	Digest Robin Spiller and Emad El-Omar Gut 2007; 56: 1177. [Extract] [Full text] [PDF] [Request Permissions]

Commentaries

	Risks and benefits of combining immunosuppressives and biological agents in inflammatory bowel disease: is the synergy worth the risk? Stephen B Hanauer Gut 2007; 56: 1181-1183. doi:10.1136/gut.2006.115980 [Extract] [Full text] [web only appendix] [PDF] [Request Permissions]
	The classics in perspective Julián Panés and Subrata Ghosh Gut 2007; 56: 1184-1186. doi:10.1136/gut.2007.121830 [Extract] [Full text] [web only appendix] [PDF] [Request Permissions]
	Fatty liver in chronic hepatitis C infection: unravelling the mechanisms Jude A Oben and Emma Paulon Gut 2007; 56: 1186-1188. doi:10.1136/gut.2006.118422 [Extract] [Full text] [PDF] [Request Permissions]

Gut tutorial

	Chronic pancreatitis: diagnosis and management of complications N I Church, S P Pereira, D Churchill, S Cairns, A R W Hatfield, and G J M Webster Gut 2007; 56: 1189-1190. doi:10.1136/gut.2007.132498 [Extract] [Full text] [PDF] [Request Permissions]   BMJ Learning: Take this module on BMJ Learning

Miscellaneous

	Acute liver failure in a patient with lung cancer K M Jamil, T Van Hagan, J Trotter, W Cheng, and N Kontorinis Gut 2007; 56: 1190. doi:10.1136/gut.2006.095547 [Extract] [Full text] [PDF] [Request Permissions]
	EDITOR’S QUIZ: GI SNAPSHOT Gut 2007; 56: 1209. doi:10.1136/gut.2006.095547a [Extract] [Full text] [PDF] [Request Permissions]
	Oesophagogastric fistula: a post-operative complication A Alzaraa, C Kelty, G Jacob, and D White Gut 2007; 56: 1225. doi:10.1136/gut.2006.105551 [Extract] [Full text] [PDF] [Request Permissions]
	EDITOR’S QUIZ: GI SNAPSHOT Gut 2007; 56: 1231. doi:10.1136/gut.2006.105551a [Extract] [Full text] [PDF] [Request Permissions]
	Sigmoid stricture in a 39-year-old female S Greco, C Penati, S Ardizzone, and G Bianchi Porro Gut 2007; 56: 1247. doi:10.1136/gut.2006.106583 [Extract] [Full text] [PDF] [Request Permissions]
	EDITOR’S QUIZ: GI SNAPSHOT Gut 2007; 56: 1256. doi:10.1136/gut.2006.106583a [Extract] [Full text] [PDF] [Request Permissions]

Gastro-oesophageal reflux

	Critical role of stress in increased oesophageal mucosa permeability and dilated intercellular spaces Ricard Farré, Rita De Vos, Karel Geboes, Kristine Verbecke, Pieter Vanden Berghe, Inge Depoortere, Kathleen Blondeau, Jan Tack, and Daniel Sifrim Gut 2007; 56: 1191-1197. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 1 February 2007. doi:10.1136/gut.2006.113688

Small bowel

	Is surveillance of the small bowel indicated for Lynch syndrome families? G L ten Kate, J H Kleibeuker, F M Nagengast, M Craanen, A Cats, F H Menko, and H F A Vasen Gut 2007; 56: 1198-1201. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 4 April 2007. doi:10.1136/gut.2006.118299

Neurogastroenterology

	Increased colonic pain sensitivity in irritable bowel syndrome is the result of an increased tendency to report pain rather than increased neurosensory sensitivity Spencer D Dorn, Olafur S Palsson, Syed I M Thiwan, Motoyori Kanazawa, W Crawford Clark, Miranda A L van Tilburg, Douglas A Drossman, Yolanda Scarlett, Rona L Levy, Yehuda Ringel, Michael D Crowell, Kevin W Olden, and William E Whitehead Gut 2007; 56: 1202-1209. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 4 May 2007. doi:10.1136/gut.2006.117390
	Urocortin II mediates pro-inflammatory effects in human colonocytes via corticotropin-releasing hormone receptor 2 Alan C Moss, Pauline Anton, Tor Savidge, Paul Newman, Adam S Cheifetz, Jerome Gay, Sophia Paraschos, Michael Weinstein Winter, Mary P Moyer, Katia Karalis, Efi Kokkotou, and Charalabos Pothoulakis Gut 2007; 56: 1210-1217. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 5 April 2007. doi:10.1136/gut.2006.110668
	Effect of a second-generation 2 ligand (pregabalin) on visceral sensation in hypersensitive patients with irritable bowel syndrome L A Houghton, C Fell, P J Whorwell, I Jones, D P Sudworth, and J D Gale Gut 2007; 56: 1218-1225. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 19 April 2007. doi:10.1136/gut.2006.110858

Inflammatory bowel disease

	Effectiveness of concomitant immunosuppressive therapy in suppressing the formation of antibodies to infliximab in Crohn’s disease Severine Vermeire, Maja Noman, Gert Van Assche, Filip Baert, Geert D’Haens, and Paul Rutgeerts Gut 2007; 56: 1226-1231. [Abstract] [Full text] [web only appendix] [PDF] [Request Permissions]   Published Online First: 17 January 2007. doi:10.1136/gut.2006.099978
	Adalimumab for maintenance treatment of Crohn’s disease: results of the CLASSIC II trial W J Sandborn, S B Hanauer, P Rutgeerts, R N Fedorak, M Lukas, D G MacIntosh, R Panaccione, D Wolf, J D Kent, B Bittle, J Li, and P F Pollack Gut 2007; 56: 1232-1239. [Abstract] [Full text] [web only appendix] [PDF] [Request Permissions]   Published Online First: 13 February 2007. doi:10.1136/gut.2006.106781
	Reduced mucosal antimicrobial activity in Crohn’s disease of the colon Sabine Nuding, Klaus Fellermann, Jan Wehkamp, and Eduard F Stange Gut 2007; 56: 1240-1247. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 24 April 2007. doi:10.1136/gut.2006.118646
	Critical role of the CD40–CD40-ligand pathway in regulating mucosal inflammation-driven angiogenesis in inflammatory bowel disease S Danese, F Scaldaferri, S Vetrano, T Stefanelli, C Graziani, A Repici, R Ricci, G Straface, A Sgambato, A Malesci, C Fiocchi, and S Rutella Gut 2007; 56: 1248-1256. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 22 February 2007. doi:10.1136/gut.2006.111989
	Interleukin 31 mediates MAP kinase and STAT1/3 activation in intestinal epithelial cells and its expression is upregulated in inflammatory bowel disease Julia Dambacher, Florian Beigel, Julia Seiderer, Dirk Haller, Burkhard Göke, Christoph J Auernhammer, and Stephan Brand Gut 2007; 56: 1257-1265. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 20 April 2007. doi:10.1136/gut.2006.118679

Pancreatic cancer

	Activation of the epidermal growth factor signalling pathway by tissue plasminogen activator in pancreas cancer cells Mariano Hurtado, Juan José Lozano, Elisabeth Castellanos, Luis A López-Fernández, Keith Harshman, Carlos Martínez-A, Angel R Ortiz, Timothy M Thomson, and Rosanna Paciucci Gut 2007; 56: 1266-1274. [Abstract] [Full text] [web only appendices] [PDF] [Request Permissions]   Published Online First: 23 April 2007. doi:10.1136/gut.2006.097188
	Dendritic cell-based vaccination combined with gemcitabine increases survival in a murine pancreatic carcinoma model C Bauer, F Bauernfeind, A Sterzik, M Orban, M Schnurr, H A Lehr, S Endres, A Eigler, and M Dauer Gut 2007; 56: 1275-1282. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 29 March 2007. doi:10.1136/gut.2006.108621

Liver disease

	MELD score and serum sodium in the prediction of survival of patients with cirrhosis awaiting liver transplantation Maria-Carlota Londoño, Andrés Cárdenas, Mónica Guevara, Llorenç Quintó, Dara de las Heras, Miguel Navasa, Antoni Rimola, Juan-Carlos Garcia-Valdecasas, Vicente Arroyo, and Pere Ginès Gut 2007; 56: 1283-1290. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 23 April 2007. doi:10.1136/gut.2006.102764
	Proton pump inhibitors suppress absorption of dietary non-haem iron in hereditary haemochromatosis Carol Hutchinson, Catherine A Geissler, Jonathan J Powell, and Adrian Bomford Gut 2007; 56: 1291-1295. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 7 March 2007. doi:10.1136/gut.2006.108613
	Post-load insulin resistance is an independent predictor of hepatic fibrosis in virus C chronic hepatitis and in non-alcoholic fatty liver disease G Svegliati-Baroni, E Bugianesi, T Bouserhal, F Marini, F Ridolfi, F Tarsetti, F Ancarani, E Petrelli, E Peruzzi, M Lo Cascio, M Rizzetto, G Marchesini, and A Benedetti Gut 2007; 56: 1296-1301. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 28 March 2007. doi:10.1136/gut.2006.107946

Hepatitis C

	The genotype 3-specific hepatitis C virus core protein residue phenylalanine 164 increases steatosis in an in vitro cellular model C Hourioux, R Patient, A Morin, E Blanchard, A Moreau, S Trassard, B Giraudeau, and P Roingeard Gut 2007; 56: 1302-1308. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 9 January 2007. doi:10.1136/gut.2006.108647

JournalScan

	JournalScan Gut 2007; 56: 1309. [Extract] [Full text] [PDF] [Request Permissions]

Recent advances in clinical practice

	Diagnosis, prevention and treatment of hepatorenal syndrome in cirrhosis Francesco Salerno, Alexander Gerbes, Pere Ginès, Florence Wong, and Vicente Arroyo Gut 2007; 56: 1310-1318. [Extract] [Full text] [PDF] [Request Permissions]   Published Online First: 27 March 2007. doi:10.1136/gut.2006.107789

Letters

	Iron deficiency anaemia: further education regarding the British Society of Gastroenterology guidelines is required Kim Gregory, Melanie Halliday, Charles Averill, Nij Bhala, Chris Tselepis, and Tariq Iqbal Gut 2007; 56: 1319. doi:10.1136/gut.2006.117838 [Extract] [Full text] [PDF] [Request Permissions]
	Association of BclI polymorphism of the glucocorticoid receptor gene locus with response to glucocorticoids in inflammatory bowel disease Sara De Iudicibus, Gabriele Stocco, Stefano Martelossi, Ilenia Drigo, Stefania Norbedo, Paolo Lionetti, Elena Pozzi, Arrigo Barabino, Giuliana Decorti, Fiora Bartoli, and Alessandro Ventura Gut 2007; 56: 1319-1320. doi:10.1136/gut.2006.116160 [Extract] [Full text] [PDF] [Request Permissions]
	MYO9B polymorphisms in patients with inflammatory bowel disease C Núñez, J Oliver, J L Mendoza, M Gómez-García, A Piñero, C Taxonera, M Díaz-Rubio, M A López-Nevot, E G de la Concha, A Nieto, E Urcelay, A Martínez, and J Martín Gut 2007; 56: 1321-1322. doi:10.1136/gut.2007.121905 [Extract] [Full text] [PDF] [Request Permissions]
	Cathepsin B gene polymorphism Val26 is not associated with idiopathic chronic pancreatitis in European patients F U Weiss, C-O Behn, P Simon, M Ruthenbürger, W Halangk, and M M Lerch Gut 2007; 56: 1322-1323. doi:10.1136/gut.2007.122507 [Extract] [Full text] [PDF] [Request Permissions]
	Familial association of benign pancreatic hyperenzymaemia and pancreatic cancer L Gullo, M Migliori, P Fusaroli, and G Caletti Gut 2007; 56: 1323-1324. doi:10.1136/gut.2007.125062 [Extract] [Full text] [PDF] [Request Permissions]
	Safe endoscopic polypectomy of jejunal polyps with a detachable snare during double balloon enteroscopy • Author’s reply M Matsushita, M Shimatani, K Uchida, K Okazaki, H-H Yen, and Y-Y Chen Gut 2007; 56: 1324-1325. [Extract] [Full text] [PDF] [Request Permissions]
	Remission and relapse of Crohn’s disease following autologous haematopoietic stem cell transplantation for non-Hodgkin’s lymphoma V Anumakonda, B Hayee, and G Chung-Faye Gut 2007; 56: 1325. [Extract] [Full text] [PDF] [Request Permissions]   Published Online First: 16 April 2007. doi:10.1136/gut.2006.111377
	Activated innate immune system in irritable bowel syndrome? J Langhorst, A Wieder, A Michalsen, F Musial, G J Dobos, and A Rueffer Gut 2007; 56: 1325-1326. [Extract] [Full text] [PDF] [Request Permissions]   Published Online First: 11 April 2007. doi:10.1136/gut.2007.125005
	Is there an association between coeliac disease and irritable bowel syndrome? J S Leeds and D S Sanders Gut 2007; 56: 1326-1327. [Extract] [Full text] [PDF] [Request Permissions]
	Risk of pancreatic cancer in patients with cystic fibrosis P Maisonneuve, B C Marshall, and A B Lowenfels Gut 2007; 56: 1327-1328. doi:10.1136/gut.2007.125278 [Extract] [Full text] [PDF] [Request Permissions]
	Glucocorticoid receptor isoform expression does not predict steroid treatment response in IBD M Hausmann, H Herfarth, J Schölmerich, and G Rogler Gut 2007; 56: 1328-1329. doi:10.1136/gut.2006.108035 [Extract] [Full text] [PDF] [Request Permissions]
	A non-invasive screen for infectivity in transmissible spongiform encephalopathies D G Glover, B J Pollard, L González, S Sisó, D Kennedy, and M Jeffrey Gut 2007; 56: 1329-1331. doi:10.1136/gut.2007.123141 [Extract] [Full text] [PDF] [Request Permissions]
	Transient elastography in patients with non-alcoholic fatty liver disease (NAFLD) M Yoneda, K Fujita, M Inamori, A Nakajima, M Tamano, and H Hiraishi Gut 2007; 56: 1330-1331. [Extract] [Full text] [erratum] [PDF] [Request Permissions]   Published Online First: 30 April 2007. doi:10.1136/gut.2007.126417

Book reviews

	The Enterobacteria, 2nd Edition Paul Everest Gut 2007; 56: 1331. doi:10.1136/gut.2007.121509 [Extract] [Full text] [PDF] [Request Permissions]
	Challenges in Colorectal Cancer Madhava Pai and Ruben Canelo Gut 2007; 56: 1332. doi:10.1136/gut.2006.106591 [Extract] [Full text] [PDF] [Request Permissions]
	Fast Facts: Inflammatory Bowel Disease, 2nd ed Marc Ferrante Gut 2007; 56: 1332. doi:10.1136/gut.2007.121400 [Extract] [Full text] [PDF] [Request Permissions]