Digest

	Digest Robin Spiller and Magnus Simren Gut 2008; 57: i-ii. [Extract] [Full text] [PDF] [Request Permissions]

Leader

	Disorders of a modern lifestyle: reconciling the epidemiology of inflammatory bowel diseases Charles N Bernstein and Fergus Shanahan Gut 2008; 57: 1185-1191. [Extract] [Full text] [PDF] [Request Permissions]   Published Online First: 30 May 2008. doi:10.1136/gut.2007.122143

Editor's quiz: GI snapshot

	An abnormal rectal flat lesion L Petruzziello, C Spada, A Crucitti, P Familiari, and G Costamagna Gut 2008; 57: 1192. doi:10.1136/gut.2007.146688 [Extract] [Full text] [PDF] [Request Permissions]
	ANSWER Gut 2008; 57: 1220. doi:10.1136/gut.2007.146688a [Extract] [Full text] [PDF] [Request Permissions]
	Ulcers and the colon: keep an open mind G W Moran, R Hejmadi, E Campbell, and R Boulton Gut 2008; 57: 1221. doi:10.1136/gut.2008.149732 [Extract] [Full text] [PDF] [Request Permissions]
	Epigastric discomfort after outpatient endoscopy L Kamper and P Haage Gut 2008; 57: 1260. doi:10.1136/gut.2007.147967 [Extract] [Full text] [PDF] [Request Permissions]
	A puzzling presentation of pancreatitis W Laleman, E Vanhoutte, D Vanbeckevoort, R Aerts, W Van Steenbergen, and C Verslype Gut 2008; 57: 1261. doi:10.1136/gut.2008.149401 [Extract] [Full text] [PDF] [Request Permissions]
	ANSWER Gut 2008; 57: 1267. doi:10.1136/gut.2008.149732a [Extract] [Full text] [PDF] [Request Permissions]
	Abdominal pain and shock in a 73-year-old patient Y-J Chen, C-C Hsieh, P-S Lai, and C-C Lee Gut 2008; 57: 1282. doi:10.1136/gut.2007.146175 [Extract] [Full text] [PDF] [Request Permissions]
	ANSWER Gut 2008; 57: 1287. doi:10.1136/gut.2008.149401a [Extract] [Full text] [PDF] [Request Permissions]
	ANSWER Gut 2008; 57: 1296. doi:10.1136/gut.2007.146175a [Extract] [Full text] [PDF] [Request Permissions]
	Metachronous multi-organ lesions in a jaundiced patient H J Kim, J H Byun, S S Lee, S H Park, M-G Lee, M-H Kim, and E S Yu Gut 2008; 57: 1297. doi:10.1136/gut.2007.138529 [Extract] [Full text] [PDF] [Request Permissions]
	ANSWER Gut 2008; 57: 1299. doi:10.1136/gut.2007.138529a [Extract] [Full text] [PDF] [Request Permissions]
	ANSWER Gut 2008; 57: 1314. doi:10.1136/gut.2007.147967a [Extract] [Full text] [PDF] [Request Permissions]

Commentaries

	Purinergic receptors as future targets for treatment of functional GI disorders Geoffrey Burnstock Gut 2008; 57: 1193-1194. doi:10.1136/gut.2008.151134 [Extract] [Full text] [PDF] [Request Permissions]
	Surveillance programmes for colorectal cancer in inflammatory bowel disease: have we got it right? Charles N Bernstein Gut 2008; 57: 1194-1196. doi:10.1136/gut.2008.152009 [Extract] [Full text] [PDF] [Request Permissions]
	Simple measures to prevent post-ERCP pancreatitis? Pier Alberto Testoni Gut 2008; 57: 1197-1198. doi:10.1136/gut.2008.153080 [Extract] [Full text] [PDF] [Request Permissions]
	Role of hedgehog signalling in bile ductular cells Ian N Hines and Richard A Rippe Gut 2008; 57: 1198-1199. doi:10.1136/gut.2008.153098 [Extract] [Full text] [PDF] [Request Permissions]

Gastro-oesophageal reflux

	Long-term results and risk factor analysis for recurrence after curative endoscopic therapy in 349 patients with high-grade intraepithelial neoplasia and mucosal adenocarcinoma in Barrett’s oesophagus O Pech, A Behrens, A May, L Nachbar, L Gossner, T Rabenstein, H Manner, E Guenter, J Huijsmans, M Vieth, M Stolte, and C Ell Gut 2008; 57: 1200-1206. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 6 May 2008. doi:10.1136/gut.2007.142539
	Comparing laparoscopic antireflux surgery with esomeprazole in the management of patients with chronic gastro-oesophageal reflux disease: a 3-year interim analysis of the LOTUS trial L Lundell, S Attwood, C Ell, R Fiocca, J-P Galmiche, J Hatlebakk, T Lind, O Junghard, and on behalf of the LOTUS trial collaborators Gut 2008; 57: 1207-1213. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 9 May 2008. doi:10.1136/gut.2008.148833

Helicobacter pylori

	Cost-effectiveness of and satisfaction with a Helicobacter pylori "test and treat" strategy compared with prompt endoscopy in young Asians with dyspepsia S Mahadeva, Y-C Chia, A Vinothini, M Mohazmi, and K-L Goh Gut 2008; 57: 1214-1220. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 25 April 2008. doi:10.1136/gut.2007.147728

Intestinal inflammation

	Protease-activated receptor-2 activation: a major actor in intestinal inflammation E Hyun, P Andrade-Gordon, M Steinhoff, and N Vergnolle Gut 2008; 57: 1222-1229. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 6 May 2008. doi:10.1136/gut.2008.150722

Neurogastroenterology

	P2X receptor-mediated visceral hyperalgesia in a rat model of chronic visceral hypersensitivity G-Y Xu, M Shenoy, J H Winston, S Mittal, and P J Pasricha Gut 2008; 57: 1230-1237. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 12 February 2008. doi:10.1136/gut.2007.134221

Colorectal cancer

	Modelling future capacity needs and spending on colonoscopy in the English bowel cancer screening programme K E Nnoaham and C Lines Gut 2008; 57: 1238-1245. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 25 April 2008. doi:10.1136/gut.2007.146050
	High frequency of early colorectal cancer in inflammatory bowel disease M W M D Lutgens, F P Vleggaar, M E I Schipper, P C F Stokkers, C J van der Woude, D W Hommes, D J de Jong, G Dijkstra, A A van Bodegraven, B Oldenburg, and M Samsom Gut 2008; 57: 1246-1251. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 12 March 2008. doi:10.1136/gut.2007.143453
	Inherited predisposition to colorectal adenomas caused by multiple rare alleles of MUTYH but not OGG1, NUDT1, NTH1 or NEIL 1, 2 or 3 A R Dallosso, S Dolwani, N Jones, S Jones, J Colley, J Maynard, S Idziaszczyk, V Humphreys, J Arnold, A Donaldson, D Eccles, A Ellis, D G Evans, I M Frayling, F J Hes, R S Houlston, E R Maher, M Nielsen, S Parry, E Tyler, V Moskvina, J P Cheadle, and J R Sampson Gut 2008; 57: 1252-1255. [Abstract] [Full text] [web only tables] [PDF] [Request Permissions]   Published Online First: 30 May 2008. doi:10.1136/gut.2007.145748
	Automated immunochemical quantitation of haemoglobin in faeces collected on cards for screening for colorectal cancer C G Fraser, C M Mathew, K McKay, F A Carey, and R J C Steele Gut 2008; 57: 1256-1260. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 8 May 2008. doi:10.1136/gut.2008.153494

Pancreas

	A meta-analysis of rectal NSAIDs in the prevention of post-ERCP pancreatitis B J Elmunzer, A K Waljee, G H Elta, J R Taylor, S M A Fehmi, and P D R Higgins Gut 2008; 57: 1262-1267. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 28 March 2008. doi:10.1136/gut.2007.140756

Hepatology

	Dissection of familial correlations in hepatitis C virus (HCV) seroprevalence suggests intrafamilial viral transmission and genetic predisposition to infection S Plancoulaine, M K Mohamed, N Arafa, I Bakr, C Rekacewicz, D-A Trégouët, D Obach, M El Daly, V Thiers, C Féray, M Abdel-Hamid, L Abel, and A Fontanet Gut 2008; 57: 1268-1274. [Abstract] [Full text] [web only appendix] [PDF] [Request Permissions]   Published Online First: 14 May 2008. doi:10.1136/gut.2007.140681
	The hedgehog pathway regulates remodelling responses to biliary obstruction in rats A Omenetti, Y Popov, Y Jung, S S Choi, R P Witek, L Yang, K D Brown, D Schuppan, and A M Diehl Gut 2008; 57: 1275-1282. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 28 March 2008. doi:10.1136/gut.2008.148619
	Waist circumference correlates with liver fibrosis in children with non-alcoholic steatohepatitis M Manco, G Bedogni, M Marcellini, R Devito, P Ciampalini, M R Sartorelli, D Comparcola, F Piemonte, and V Nobili Gut 2008; 57: 1283-1287. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 24 January 2008. doi:10.1136/gut.2007.142919
	Reliability of transient elastography for the diagnosis of advanced fibrosis in chronic hepatitis C U Arena, F Vizzutti, J G Abraldes, G Corti, C Stasi, S Moscarella, S Milani, E Lorefice, A Petrarca, R G Romanelli, G Laffi, J Bosch, F Marra, and M Pinzani Gut 2008; 57: 1288-1293. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 30 April 2008. doi:10.1136/gut.2008.149708

Case reports

	Use of sirolimus (rapamycin) to treat refractory Crohn’s disease D C O Massey, F Bredin, and M Parkes Gut 2008; 57: 1294-1296. doi:10.1136/gut.2008.157297 [Abstract] [Full text] [PDF] [Request Permissions]

JournalScan

	JournalScan Gut 2008; 57: 1298. [Extract] [Full text] [PDF] [Request Permissions]

Recent advances in basic science

	Mechanisms of extrahepatic vasodilation in portal hypertension M Hennenberg, J Trebicka, T Sauerbruch, and J Heller Gut 2008; 57: 1300-1314. [Abstract] [Full text] [PDF] [Request Permissions]   Published Online First: 29 April 2008. doi:10.1136/gut.2007.144584

Recent advances in clinical practice

	The small intestinal bacterial overgrowth. Irritable bowel syndrome hypothesis: implications for treatment S Vanner Gut 2008; 57: 1315-1321. [Extract] [Full text] [PDF] [Request Permissions]   Published Online First: 4 February 2008. doi:10.1136/gut.2007.133629

Guidelines

	Guidelines for the management of anticoagulant and antiplatelet therapy in patients undergoing endoscopic procedures A M Veitch, T P Baglin, A H Gershlick, S M Harnden, R Tighe, and S Cairns Gut 2008; 57: 1322-1329. [Extract] [Full text] [PDF] [Request Permissions]   Published Online First: 9 May 2008. doi:10.1136/gut.2007.142497

PostScript

	Crohn’s-like enterocolitis associated with mycophenolic acid treatment D Dost, M E van Leerdam, H van Dekken, W Weimar, E J Kuipers, A H Bijl, and T van Gelder Gut 2008; 57: 1330. doi:10.1136/gut.2007.139972 [Extract] [Full text] [PDF] [Request Permissions]
	Iron deficiency anaemia guidelines: time for an update? J K Turner and J Green Gut 2008; 57: 1330-1331. [Extract] [Full text] [PDF] [Request Permissions]
	Narrow-band imaging and detection of colorectal adenoma K-H Lok and M-L Szeto Gut 2008; 57: 1331. [Extract] [Full text] [PDF] [Request Permissions]
	In vivo diagnosis of intestinal spirochaetosis by confocal endomicroscopy U Günther, H-J Epple, F Heller, C Loddenkemper, M Grünbaum, T Schneider, M Zeitz, and C Bojarski Gut 2008; 57: 1331-1333. [Extract] [Full text] [PDF] [Request Permissions]
	The effects of population-based faecal occult blood test screening upon emergency colorectal cancer admissions in Coventry and north Warwickshire R F A Logan Gut 2008; 57: 1333. [Extract] [Full text] [PDF] [Request Permissions]
	Author’s response S J Goodyear Gut 2008; 57: 1333-1334. [Extract] [Full text] [PDF] [Request Permissions]
	More polyp detection: narrow-band imaging or a transparent hood? M Matsushita, M Omiya, K Uchida, A Nishio, and K Okazaki Gut 2008; 57: 1334. [Extract] [Full text] [PDF] [Request Permissions]
	The prevalence of small intestinal bacterial overgrowth in irritable bowel syndrome: IBS vs healthy controls (not historical definitions) M Pimentel Gut 2008; 57: 1334-1335. [Extract] [Full text] [PDF] [Request Permissions]
	Authors’ reply M Simrén, I Posserud, P-O Stotzer, E S Björnsson, and H Abrahamsson Gut 2008; 57: 1335. [Extract] [Full text] [PDF] [Request Permissions]
	Genetic variants in the autophagy pathway contribute to paediatric Crohn’s disease N Peterson, S Guthery, L Denson, J Lee, S Saeed, S Prahalad, V Biank, R Ehlert, G Tomer, R Grand, C Rudolph, and S Kugathasan Gut 2008; 57: 1336-1337. doi:10.1136/gut.2008.152207 [Extract] [Full text] [PDF] [Request Permissions]
	Authors’ reply M Parkes and D C O Massey Gut 2008; 57: 1337. [Extract] [Full text] [PDF] [Request Permissions]
	Early management of severe acute biliary pancreatitis: wind of change M S Petrov Gut 2008; 57: 1337-1338. [Extract] [Full text] [PDF] [Request Permissions]
	Authors’ reply E J Williams, J Green, I Beckingham, R Parks, D Martin, and M Lombard Gut 2008; 57: 1338. [Extract] [Full text] [PDF] [Request Permissions]
	Somatostatin analogues reduce liver volume in polycystic liver disease L van Keimpema, R A de Man, and J P H Drenth Gut 2008; 57: 1338-1339. doi:10.1136/gut.2008.155721 [Extract] [Full text] [PDF] [Request Permissions]
	GI epidemiology Richard F A Logan Gut 2008; 57: 1339. [Extract] [Full text] [PDF] [Request Permissions]
	Intestinal failure. Diagnosis, management and transplantation Alastair Forbes Gut 2008; 57: 1339-1340. [Extract] [Full text] [PDF] [Request Permissions]
	Endoscopy in a new light... Peter D Fairclough Gut 2008; 57: 1340. [Extract] [Full text] [PDF] [Request Permissions]
	CORRECTIONS Gut 2008; 57: 1340. doi:10.1136/gut.2007.137703corr1 [Extract] [Full text] [PDF] [Request Permissions]
	CORRECTIONS Gut 2008; 57: 1340. doi:10.1136/gut.2007.129296corr1 [Extract] [Full text] [PDF] [Request Permissions]