Digest:

Digest

Robin Spiller, Robin Spiller, and Magnus Simren

Gut 2009; 58: i-ii.

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Commentaries:

Epigenetic changes wipe out protective mechanisms in Barrett’s oesophagus

Rebecca C Fitzgerald

Gut 2009; 58: 1-2. doi:10.1136/gut.2008.162446

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Chronic intestinal pseudo-obstruction: how important is JC virus infection?

Greger Lindberg

Gut 2009; 58: 2-3. doi:10.1136/gut.2008.160101

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After budesonide, what next for collagenous colitis?

Darrell S Pardi

Gut 2009; 58: 3-4. doi:10.1136/gut.2008.163477

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Upper gastrointestinal cancer:

DNA hypermethylation regulates the expression of members of the Mu-class glutathione S-transferases and glutathione peroxidases in Barrett’s adenocarcinoma

D F Peng, M Razvi, H Chen, K Washington, A Roessner, R Schneider-Stock, and W El-Rifai

Gut 2009; 58: 5-15.
Published Online First: 29 July 2008. doi:10.1136/gut.2007.146290

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Oesophageal and gastric intestinal-type adenocarcinomas show the same male predominance due to a 17 year delayed development in females

M H Derakhshan, S Liptrot, J Paul, I L Brown, D Morrison, and K E L McColl

Gut 2009; 58: 16-23.
Published Online First: 6 October 2008. doi:10.1136/gut.2008.161331

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Editor's quiz:

How can a large gallstone give rise to chronic diarrhoea?

F Parente, A Colli, M Costa, S Bargiggia, and S Greco

Gut 2009; 58: 24. doi:10.1136/gut.2008.158667

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Abdominal pain after attempted endoscopic mucosal resection of a right-sided colonic lesion

S Sarkar, V Tagore, and D White

Gut 2009; 58: 33. doi:10.1136/gut.2008.158568

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A rare cause of portal hypertension

S Sen, S M Rushbrook, T C See, and W J H Griffiths

Gut 2009; 58: 59. doi:10.1136/gut.2008.161505

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Rapid-onset febrile dermatosis

M Décisier, V Duhalde, P Faure, A Ammoury, M Gony, J Moreau, J L Montastruc, and H Bagheri

Gut 2009; 58: 67. doi:10.1136/gut.2008.156737

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Neurogastroenterology:

JC virus infects the enteric glia of patients with chronic idiopathic intestinal pseudo-obstruction

M Selgrad, R De Giorgio, L Fini, R F Cogliandro, S Williams, V Stanghellini, G Barbara, M Tonini, R Corinaldesi, R M Genta, R Domiati-Saad, R Meyer, A Goel, C R Boland, and L Ricciardiello

Gut 2009; 58: 25-32.
Published Online First: 1 July 2008. doi:10.1136/gut.2008.152512

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Inflammatory bowel disease:

Melanin-concentrating hormone (MCH) modulates C difficile toxin A-mediated enteritis in mice

E Kokkotou, D O Espinoza, D Torres, I Karagiannides, S Kosteletos, T Savidge, M O’Brien, and C Pothoulakis

Gut 2009; 58: 34-40.
Published Online First: 29 September 2008. doi:10.1136/gut.2008.155341

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Reducing small intestinal permeability attenuates colitis in the IL10 gene-deficient mouse

M C Arrieta, K Madsen, J Doyle, and J Meddings

Gut 2009; 58: 41-48.
Published Online First: 1 October 2008. doi:10.1136/gut.2008.150888

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Regulation of intestinal barrier function by signal transducer and activator of transcription 5b

X Han, X Ren, I Jurickova, K Groschwitz, B A Pasternak, H Xu, T A Wilson, S P Hogan, and L A Denson

Gut 2009; 58: 49-58.
Published Online First: 7 August 2008. doi:10.1136/gut.2007.145094

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Linkage of Crohn’s disease-related serological phenotypes: NFKB1 haplotypes are associated with anti-CBir1 and ASCA, and show reduced NF-B activation

H Takedatsu, K D Taylor, L Mei, D P B McGovern, C J Landers, R Gonsky, Y Cong, E A Vasiliauskas, A Ippoliti, C O Elson, J I Rotter, and S R Targan

Gut 2009; 58: 60-67.
Published Online First: 2 October 2008. doi:10.1136/gut.2008.156422

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Long-term budesonide treatment of collagenous colitis: a randomised, double-blind, placebo-controlled trial

O K Bonderup, J B Hansen, P S Teglbjærg, L A Christensen, and J F Fallingborg

Gut 2009; 58: 68-72.
Published Online First: 31 July 2008. doi:10.1136/gut.2008.156513

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Endoscopy:

Computed virtual chromoendoscopy versus standard colonoscopy with targeted indigocarmine chromoscopy: a randomised multicentre trial

J Pohl, E Lotterer, C Balzer, M Sackmann, K-D Schmidt, L Gossner, C Schaab, T Frieling, M Medve, G Mayer, M Nguyen-Tat, and C Ell

Gut 2009; 58: 73-78.
Published Online First: 6 October 2008. doi:10.1136/gut.2008.153601

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Colorectal neoplasia:

Multiple putative oncogenes at the chromosome 20q amplicon contribute to colorectal adenoma to carcinoma progression

B Carvalho, C Postma, S Mongera, E Hopmans, S Diskin, M A van de Wiel, W van Criekinge, O Thas, A Matthäi, M A Cuesta, J S Terhaar sive Droste, M Craanen, E Schröck, B Ylstra, and G A Meijer

Gut 2009; 58: 79-89.
Published Online First: 1 October 2008. doi:10.1136/gut.2007.143065

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CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer

Shuji Ogino, Katsuhiko Nosho, Gregory J Kirkner, Takako Kawasaki, Jeffrey A Meyerhardt, Massimo Loda, Edward L Giovannucci, and Charles S Fuchs

Gut 2009; 58: 90-96.
Published Online First: 2 October 2008. doi:10.1136/gut.2008.155473

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Editor's quiz: GI snapshot:

Answer

Gut 2009; 58: 89. doi:10.1136/gut.2008.158667a

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ANSWER

Gut 2009; 58: 104. doi:10.1136/gut.2008.158568a

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ANSWER

Gut 2009; 58: 125. doi:10.1136/gut.2008.156737a

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ANSWER

Gut 2009; 58: 144. doi:10.1136/gut.2008.161505a

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Pancreas:

The natural history of hereditary pancreatitis: a national series

V Rebours, M-C Boutron-Ruault, M Schnee, C Férec, C Le Maréchal, O Hentic, F Maire, P Hammel, P Ruszniewski, and P Lévy

Gut 2009; 58: 97-103.
Published Online First: 28 August 2008. doi:10.1136/gut.2008.149179

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Hepatology:

Costs and cost-effectiveness of different follow-up schedules for detection of occupational hepatitis C virus infection

S Deuffic-Burban, D Abiteboul, F Lot, M Branger, E Bouvet, and Y Yazdanpanah

Gut 2009; 58: 105-110.
Published Online First: 29 September 2008. doi:10.1136/gut.2007.145516

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Metabolic syndrome increases the risk of liver cirrhosis in chronic hepatitis B

G L-H Wong, V W-S Wong, P C-L Choi, A W-H Chan, A M-L Chim, K K-L Yiu, H-Y Chan, F K-L Chan, J J-Y Sung, and H L-Y Chan

Gut 2009; 58: 111-117.
Published Online First: 2 October 2008. doi:10.1136/gut.2008.157735

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Superoxide dismutase gene transfer reduces portal pressure in CCl₄ cirrhotic rats with portal hypertension

B Laviña, J Gracia-Sancho, A Rodríguez-Vilarrupla, Y Chu, D D Heistad, J Bosch, and J C García-Pagán

Gut 2009; 58: 118-125.
Published Online First: 1 October 2008. doi:10.1136/gut.2008.149880

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JournalScan:

Journal scan

Gut 2009; 58: 126.

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Recent advances in basic science:

Biomarkers of response to therapy in oesophago-gastric cancer

K R Fareed, P Kaye, I N Soomro, M Ilyas, S Martin, S L Parsons, and S Madhusudan

Gut 2009; 58: 127-143. doi:10.1136/gut.2008.155861

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PostScript:

Does antidepressant medication in patients with hepatitis C undergoing interferon treatment reduce therapeutic efficacy?

G Robaeys, M C Wichers, J De Bie, G H Koek, F Buntinx, and J Van Os

Gut 2009; 58: 145. doi:10.1136/gut.2008.156919

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Authors’ response

M R Kraus, A Schäfer, and M Scheurlen

Gut 2009; 58: 145-146.

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Letter in response to ‘Unacceptable variation in abdominoperineal excision rates for rectal cancer: time to intervene?’

J Murphy, D Boyle, C Bhan, and N S Williams

Gut 2009; 58: 146.

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Authors’ response

E Morris, P Quirke, J D Thomas, L Fairley, B Cottier, and D Forman

Gut 2009; 58: 146-147.

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Unacceptable variation in abdominoperineal excision rates for rectal cancer: a surgeon’s response

M D Clarke

Gut 2009; 58: 147.

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Unacceptable variation in abdominoperineal excision rates for rectal cancer: a surgeon’s response. Authors’ response

E Morris, P Quirke, J Thomas, L Fairley, B Cottier, and D Forman

Gut 2009; 58: 147-148.

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Fatal invasive pulmonary aspergillosis associated with adalimumab therapy

M Manz, C Beglinger, and S R Vavricka

Gut 2009; 58: 149. doi:10.1136/gut.2008.161638

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Fatigue in non-alcoholic fatty liver disease: is there a role for hypothyroidism

E Kalaitzakis

Gut 2009; 58: 149-150.

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Authors’ response

J Newton and C P Day

Gut 2009; 58: 150.

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Unacceptable variation in abdominoperineal excision rates for rectal cancer

O Faiz, J Smith, and S Clark

Gut 2009; 58: 150.

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Authors’ response

E Morris, P Quirke, J Thomas, L Fairley, B Cottier, and D Forman

Gut 2009; 58: 150-152.

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Transient development of anti-mitochondrial antibodies accompanies autoimmune hepatitis–sclerosing cholangitis overlap

M Bhat, M Guindi, E J Heathcote, and G M Hirschfield

Gut 2009; 58: 152-153. doi:10.1136/gut.2008.163220

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The type of the patient should be considered on discontinuation of anticoagulant and antiplatelet therapy

S-Y Lee

Gut 2009; 58: 153-154.

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Authors’ response

A M Veitch and S Cairns

Gut 2009; 58: 154. doi:10.1136/gut.2008.165308

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No TGFBRII germline mutations in juvenile polyposis patients without SMAD4 or BMPR1A mutation

L A A Brosens, W A van Hattem, M C E Kools, C Ezendam, F H Morsink, W W J de Leng, F M Giardiello, and G J A Offerhaus

Gut 2009; 58: 154-156. doi:10.1136/gut.2008.161232

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Gut tutorial:

Dyspnoea in a patient with cirrhosis

M W James, Nick Taylor, and Guruprasad P Aithal

Gut 2009; 58: 156. doi:10.1136/gut.2008.170795

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