Digest:

Digest

Robin Spiller and Severine Vermeire

Gut 2009; 58: i-ii. doi:10.1136/gut.2009.196022

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Leading articles:

The European (ECCO) Consensus on infection in IBD: what does it change for the clinician?

Jean-François Rahier, Yazdan Yazdanpanah, Jean-Frédéric Colombel, and Simon Travis

Gut 2009; 58: 1313-1315. doi:10.1136/gut.2008.175950

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Editor's quiz:

Difficulty in swallowing

H-H Liang, W Wang, C Tiong, C-C Chang, M-T Huang, J-S Chu, C-H Wu, and P-L Wei

Gut 2009; 58: 1316. doi:10.1136/gut.2008.174805

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Epigastric pain in a man with previous subtotal gastrectomy

H-C Lai, C-C Tsai, C-L Feng, C-J Yu, J-W Chou, W-H Huang, C-H Hsu, K-S Cheng, and C-Y Peng

Gut 2009; 58: 1332. doi:10.1136/gut.2008.171389

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History reveals the cause of rectal bleeding

C Messidoro, L Berk, and A P Rietveld

Gut 2009; 58: 1352. doi:10.1136/gut.2008.169193

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Dysphagia in a 27-year-old man

A Seicean and R Stan

Gut 2009; 58: 1353. doi:10.1136/gut.2008.174557

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Commentaries:

Differences in post-inflammatory hypersensitivity between splanchnic and pelvic afferents: mechanisms and implications for human disease

David J Levinthal and Klaus Bielefeldt

Gut 2009; 58: 1317-1318. doi:10.1136/gut.2009.181925

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Plasma microRNAs: a potential biomarker for colorectal cancer?

Aaron J Schetter and Curtis C Harris

Gut 2009; 58: 1318-1319. doi:10.1136/gut.2009.176875

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Albumin and stellate cell activation: wonders will never cease!

Massimo Pinzani

Gut 2009; 58: 1319-1321. doi:10.1136/gut.2009.182022

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Screening for familial pancreatic cancer: is doing something better than doing nothing?

Randall E Brand

Gut 2009; 58: 1321-1322. doi:10.1136/gut.2009.181214

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Gastric cancer:

Green tea consumption and gastric cancer in Japanese: a pooled analysis of six cohort studies

M Inoue, S Sasazuki, K Wakai, T Suzuki, K Matsuo, T Shimazu, I Tsuji, K Tanaka, T Mizoue, C Nagata, A Tamakoshi, N Sawada, S Tsugane, and for the Research Group for the Development and Evaluation of Cancer Prevention Strategies in Japan

Gut 2009; 58: 1323-1332.
Published Online First: 7 June 2009. doi:10.1136/gut.2008.166710

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Neurogastroenterology:

Post-inflammatory colonic afferent sensitisation: different subtypes, different pathways and different time courses

P A Hughes, S M Brierley, C M Martin, S J H Brookes, D R Linden, and L A Blackshaw

Gut 2009; 58: 1333-1341.
Published Online First: 25 March 2009. doi:10.1136/gut.2008.170811

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Transient receptor potential A1 mediates gastric distention-induced visceral pain in rats

T Kondo, K Obata, K Miyoshi, J Sakurai, J Tanaka, H Miwa, and K Noguchi

Gut 2009; 58: 1342-1352.
Published Online First: 9 June 2009. doi:10.1136/gut.2008.175901

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Edior's quiz:

A "stitch in time"

D Prichard, A Zaheer, N Ravi, J Reynolds, and N Mahmud

Gut 2009; 58: 1341. doi:10.1136/gut.2008.169508

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Inflammatory bowel disease:

Steroid-sparing properties of sargramostim in patients with corticosteroid-dependent Crohn’s disease: a randomised, double-blind, placebo-controlled, phase 2 study

J F Valentine, R N Fedorak, B Feagan, P Fredlund, R Schmitt, P Ni, and T J Humphries

Gut 2009; 58: 1354-1362.
Published Online First: 7 June 2009. doi:10.1136/gut.2008.165738

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Anti-CTLA-4 treatment induces IL-10-producing ICOS⁺ regulatory T cells displaying IDO-dependent anti-inflammatory properties in a mouse model of colitis

C Coquerelle, G Oldenhove, V Acolty, J Denoeud, G Vansanten, J-M Verdebout, A Mellor, J A Bluestone, and M Moser

Gut 2009; 58: 1363-1373.
Published Online First: 7 June 2009. doi:10.1136/gut.2008.162842

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Colorectal cancer:

Differential expression of microRNAs in plasma of patients with colorectal cancer: a potential marker for colorectal cancer screening

E K O Ng, W W S Chong, H Jin, E K Y Lam, V Y Shin, J Yu, T C W Poon, S S M Ng, and J J Y Sung

Gut 2009; 58: 1375-1381.
Published Online First: 6 February 2009. doi:10.1136/gut.2008.167817

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Pancreas:

Formation of vitamin A lipid droplets in pancreatic stellate cells requires albumin

N Kim, W Yoo, J Lee, H Kim, H Lee, Y-S Kim, D-U Kim, and J Oh

Gut 2009; 58: 1382-1390.
Published Online First: 16 March 2009. doi:10.1136/gut.2008.170233

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Pancreatic cancer:

CD147 silencing inhibits lactate transport and reduces malignant potential of pancreatic cancer cells in in vivo and in vitro models

W Schneiderhan, M Scheler, K-H Holzmann, M Marx, J E Gschwend, M Bucholz, T M Gress, T Seufferlein, G Adler, and F Oswald

Gut 2009; 58: 1391-1398.
Published Online First: 7 June 2009. doi:10.1136/gut.2009.181412

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HDAC2 mediates therapeutic resistance of pancreatic cancer cells via the BH3-only protein NOXA

P Fritsche, B Seidler, S Schüler, A Schnieke, M Göttlicher, R M Schmid, D Saur, and G Schneider

Gut 2009; 58: 1399-1409.
Published Online First: 14 June 2009. doi:10.1136/gut.2009.180711

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Five years of prospective screening of high-risk individuals from families with familial pancreatic cancer

P Langer, P H Kann, V Fendrich, N Habbe, M Schneider, M Sina, E P Slater, J T Heverhagen, T M Gress, M Rothmund, and D K Bartsch

Gut 2009; 58: 1410-1418.
Published Online First: 25 May 2009. doi:10.1136/gut.2008.171611

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Gut tutorial:

"A flare" in a patient with known inflammatory bowel disease

Giles Major

Gut 2009; 58: 1398. doi:10.1136/gut.2009.195107

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Hepatology:

Weight gain within the normal weight range predicts ultrasonographically detected fatty liver in healthy Korean men

Y Chang, S Ryu, E Sung, H-Y Woo, S-I Cho, S-H Yoo, H-Y Ahn, and N-K Choi

Gut 2009; 58: 1419-1425.
Published Online First: 7 June 2009. doi:10.1136/gut.2008.161885

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JournalScan:

JournalScan

Gut 2009; 58: 1426. doi:10.1136/gut.2009.194084

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Recent advances in clinical practice:

Inflammatory bowel disease and lymphoproliferative disorders: the dust is starting to settle

H Sokol and L Beaugerie

Gut 2009; 58: 1427-1436. doi:10.1136/gut.2009.181982

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