Digest:

Digest

Robin Spiller and Magnus Simren

Gut 2009; 58: i-ii.

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Leading articles:

The role of adiponectin in inflammatory gastrointestinal diseases

Andreas Schäffler and Jürgen Schölmerich

Gut 2009; 58: 317-322. doi:10.1136/gut.2008.159210

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Editor's quiz:

Progressive changes on CT scanning of the liver

C J Valerio, M Shale, P Tait, and D Westaby

Gut 2009; 58: 322. doi:10.1136/gut.2008.160010

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A genetic cause for skin lumps and diarrhoea

R P Arasaradnam, H Jarvis, G Waight, R Prajapati, O Adesanya, and C Nwokolo

Gut 2009; 58: 330. doi:10.1136/gut.2008.162958

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Abdominal distension in a patient with Crohn’s disease

C-H Tseng, K-L Liu, J-M Liou, H-P W, and M-S Wu

Gut 2009; 58: 346. doi:10.1136/gut.2008.161547

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ANSWER

Gut 2009; 58: 366. doi:10.1136/gut.2008.160010a

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Anal ulceration in a young man

J D Zeitoun, R Kaci, T Homsi, O Hermine, and V de Parades

Gut 2009; 58: 403. doi:10.1136/gut.2008.152504

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Imaging after medically managed severe acute cholecystitis

T J Walton, R Dhingsa, P V Kaye, and D N Lobo

Gut 2009; 58: 421. doi:10.1136/gut.2008.164970

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ANSWER

Gut 2009; 58: 430. doi:10.1136/gut.2008.152504a

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ANSWER

Gut 2009; 58: 450. doi:10.1136/gut.2008.161547a

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ANSWER

Gut 2009; 58: 464. doi:10.1136/gut.2008.162958a

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ANSWER

Gut 2009; 58: 472. doi:10.1136/gut.2008.164970a

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Commentaries:

Genetic analysis to predict prognosis at the onset of Crohn’s disease: not yet ready for prime time?

Severine Vermeire, Gert Van Assche, and Paul Rutgeerts

Gut 2009; 58: 323-324. doi:10.1136/gut.2008.162420

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Understanding the delayed onset of action of azathioprine in IBD: are we there yet?

Imke Atreya and Markus F Neurath

Gut 2009; 58: 325-326. doi:10.1136/gut.2008.163485

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Impact of resistant starch on colonic crypt cytokinetics and cell cycle regulatory genes

Ian T Johnson

Gut 2009; 58: 327-328. doi:10.1136/gut.2008.170209

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A unique pancreatic mitochondrial response to calcium and its role in apoptosis

Walter Halangk and Markus M Lerch

Gut 2009; 58: 328-330. doi:10.1136/gut.2008.160069

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Gastric cancer:

Endoscopic submucosal dissection for early gastric cancer: a large-scale feasibility study

H Isomoto, S Shikuwa, N Yamaguchi, E Fukuda, K Ikeda, H Nishiyama, K Ohnita, Y Mizuta, J Shiozawa, and S Kohno

Gut 2009; 58: 331-336.
Published Online First: 10 November 2008. doi:10.1136/gut.2008.165381

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Neurogastroenterology:

Expression of taste molecules in the upper gastrointestinal tract in humans with and without type 2 diabetes

R L Young, K Sutherland, N Pezos, S M Brierley, M Horowitz, C K Rayner, and L A Blackshaw

Gut 2009; 58: 337-346.
Published Online First: 27 November 2008. doi:10.1136/gut.2008.148932

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Water-soluble CO-releasing molecules reduce the development of postoperative ileus via modulation of MAPK/HO-1 signalling and reduction of oxidative stress

O De Backer, E Elinck, B Blanckaert, L Leybaert, R Motterlini, and R A Lefebvre

Gut 2009; 58: 347-356.
Published Online First: 20 November 2008. doi:10.1136/gut.2008.155481

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Prucalopride (Resolor) in the treatment of severe chronic constipation in patients dissatisfied with laxatives

J Tack, M van Outryve, G Beyens, R Kerstens, and L Vandeplassche

Gut 2009; 58: 357-365.
Published Online First: 5 November 2008. doi:10.1136/gut.2008.162404

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Irritable bowel syndrome:

Efficacy of antidepressants and psychological therapies in irritable bowel syndrome: systematic review and meta-analysis

A C Ford, N J Talley, P S Schoenfeld, E M M Quigley, and P Moayyedi

Gut 2009; 58: 367-378.
Published Online First: 10 November 2008. doi:10.1136/gut.2008.163162

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Inflammatory bowel disease:

Role of alkaline phosphatase in colitis in man and rats

A Tuin, K Poelstra, A de Jager-Krikken, L Bok, W Raaben, M P Velders, and G Dijkstra

Gut 2009; 58: 379-387.
Published Online First: 13 October 2008. doi:10.1136/gut.2007.128868

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Molecular prediction of disease risk and severity in a large Dutch Crohn’s disease cohort

R K Weersma, P C F Stokkers, A A van Bodegraven, R A van Hogezand, H W Verspaget, D J de Jong, C J van der Woude, B Oldenburg, R K Linskens, E A M Festen, G van der Steege, D W Hommes, J B A Crusius, C Wijmenga, I M Nolte, G Dijkstra, and The Dutch Initiative on Crohn and Colitis (ICC)

Gut 2009; 58: 388-395.
Published Online First: 29 September 2008. doi:10.1136/gut.2007.144865

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Early preservation of effector functions followed by eventual T cell memory depletion: a model for the delayed onset of the effect of thiopurines

S Ben-Horin, I Goldstein, E Fudim, O Picard, Z Yerushalmi, I Barshack, I Bank, Y Goldschmid, S Bar Meir, L Mayer, and Y Chowers

Gut 2009; 58: 396-403.
Published Online First: 2 October 2008. doi:10.1136/gut.2008.157339

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Colonic cancer:

Laser microdissection expression profiling of marginal edges of colorectal tumours reveals evidence of increased lactate metabolism in the aggressive phenotype

C C Thorn, T C Freeman, N Scott, P J Guillou, and D G Jayne

Gut 2009; 58: 404-412.
Published Online First: 31 October 2008. doi:10.1136/gut.2008.157255

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Cell kinetics and gene expression changes in colorectal cancer patients given resistant starch: a randomised controlled trial

S S Dronamraju, J M Coxhead, S B Kelly, J Burn, and J C Mathers

Gut 2009; 58: 413-420.
Published Online First: 31 October 2008. doi:10.1136/gut.2008.162933

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Pancreas:

Enhanced susceptibility to pancreatitis in severe hypertriglyceridaemic lipoprotein lipase-deficient mice and agonist-like function of pancreatic lipase in pancreatic cells

Y Wang, L Sternfeld, F Yang, J A Rodriguez, C Ross, M R Hayden, F Carriere, G Liu, W Hofer, and I Schulz

Gut 2009; 58: 422-430.
Published Online First: 20 October 2008. doi:10.1136/gut.2007.146258

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Mechanisms regulating cytochrome c release in pancreatic mitochondria

I V Odinokova, K-F Sung, O A Mareninova, K Hermann, Y Evtodienko, A Andreyev, I Gukovsky, and A S Gukovskaya

Gut 2009; 58: 431-442.
Published Online First: 2 July 2008. doi:10.1136/gut.2007.147207

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Hepatology:

The systemic inflammatory response syndrome is predictive of renal dysfunction in patients with non-paracetamol-induced acute liver failure

J A Leithead, J W Ferguson, C M Bates, J S Davidson, A Lee, A J Bathgate, P C Hayes, and K J Simpson

Gut 2009; 58: 443-449.
Published Online First: 10 November 2008. doi:10.1136/gut.2008.154120

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JournalScan:

JournalScan

Gut 2009; 58: 451.

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Recent advances in clinical practice:

Immunosuppression for liver transplantation

E K Geissler and H J Schlitt

Gut 2009; 58: 452-463.
Published Online First: 3 December 2008. doi:10.1136/gut.2008.163527

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PostScript:

The usefulness of ultrasound diagnosis specifically in taeniasis

M T Galán-Puchades and M V Fuentes

Gut 2009; 58: 465.

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TRPV1-expressing sensory fibres and IBS: links with immune function

P A Hughes, S M Brierley, C M Martin, T Liebregts, J Persson, B Adam, G Holtmann, and L A Blackshaw

Gut 2009; 58: 465-466. doi:10.1136/gut.2008.161760

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Acute fatty liver in pregnancy in the UK

C L Ch’ng, J G C Kingham, and M Morgan

Gut 2009; 58: 467.

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Authors’ response

M Knight, C Nelson-Piercy, J J Kurinczuk, P Spark, P Brocklehurst on behalf of UKOSS

Gut 2009; 58: 467-468.

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Managing anticoagulated atrial fibrillation patients undergoing endoscopy

D A Gorard

Gut 2009; 58: 468.

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Authors’ response

A M Veitch and T P Baglin

Gut 2009; 58: 469.

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Fast-food hyper-alimentation and exercise restriction in healthy subjects

R D Johnston, G P Aithal, S D Ryder, and I A MacDonald

Gut 2009; 58: 469-470.

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Authors’ response

F H Nystrom and S Kechagias

Gut 2009; 58: 470.

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Cholestatic liver disease

G R Foster

Gut 2009; 58: 471. doi:10.1136/gut.2008.159004

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