Digest:

Digest

Robin Spiller and Severine Vermeire

Gut 2009; 58: i-ii. doi:10.1136/gut.2009.193219

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Leading articles:

Genetics of ulcerative colitis: the come-back of interleukin 10

Edouard Louis, Cecile Libioulle, Catherine Reenaers, Jacques Belaiche, and Michel Georges

Gut 2009; 58: 1173-1176. doi:10.1136/gut.2008.169235

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Editor's quiz:

Epigastric pain and elevated pancreatic enzymes

M Khreiss, K M Musallam, A Soweid, G Zaatari, A S Yakan, and F R Jamali

Gut 2009; 58: 1176. doi:10.1136/gut.2008.173773

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A cause for concern? An asymptomatic mesenteric lesion

J Iqbal, P Isaacs, M Sissons, R Bury, M Khurshid, and M Akhtar

Gut 2009; 58: 1184. doi:10.1136/gut.2008.166769

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Right pelvic mass in a patient with a radically resected carcinoid of the appendix

N Fazio, F Luca, L Monfardini, G Pelosi, L Bodei, K Lorizzo, G Di Meglio, B Gibelli, D Ravizza, G Bonomo, C M Grana, S Baio, M Squadroni, G Paganelli, and F de Braud

Gut 2009; 58: 1200. doi:10.1136/gut.2008.167452

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Gastrointestinal bleeding diagnosed using video capsule endoscopy

H Sokol, P Seksik, D Wendum, J Bellanger, Y Parc, J Cosnes, and L Beaugerie

Gut 2009; 58: 1206. doi:10.1136/gut.2008.172155

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Atypical dyspepsia

R Palmer, F MacLeod, and J Marshall

Gut 2009; 58: 1217. doi:10.1136/gut.2008.164723

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Commentaries:

Genetic risk for colitis-associated colorectal cancer

Edus H Warren

Gut 2009; 58: 1177-1179. doi:10.1136/gut.2009.181206

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The modulation of IGF-1 signalling by the intestine-specific factor CDX2

Jesse K Liu and John P Lynch

Gut 2009; 58: 1179-1180. doi:10.1136/gut.2009.179291

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Transluminal endoscopic necrosectomy for pancreatic necrosis: in all hands and for all patients, or with selected endoscopists in selected patients?

Marc Barthet and Salah Ezzedine

Gut 2009; 58: 1180-1182. doi:10.1136/gut.2009.180588

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Prevention of early variceal rebleeding adding banding to terlipressin therapy

Francesco Salerno and Massimo Cazzaniga

Gut 2009; 58: 1182-1183. doi:10.1136/gut.2009.182006

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Oesophagus:

Functional heartburn has more in common with functional dyspepsia than with non-erosive reflux disease

E Savarino, D Pohl, P Zentilin, P Dulbecco, G Sammito, L Sconfienza, S Vigneri, G Camerini, R Tutuian, and V Savarino

Gut 2009; 58: 1185-1191.
Published Online First: 20 May 2009. doi:10.1136/gut.2008.175810

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A proof-of-concept study evaluating the effect of ADX10059, a metabotropic glutamate receptor-5 negative allosteric modulator, on acid exposure and symptoms in gastro-oesophageal reflux disease

C Keywood, M Wakefield, and J Tack

Gut 2009; 58: 1192-1199.
Published Online First: 20 May 2009. doi:10.1136/gut.2008.162040

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Intestinal inflammation:

Age-dependent differences in galanin-dependent colonic fluid secretion after infection with Salmonella typhimurium

K Matkowskyj, S V Royan, A Blunier, G Hecht, M Rao, and R V Benya

Gut 2009; 58: 1201-1206. doi:10.1136/gut.2008.163832

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The role of the novel Th17 cytokine IL-26 in intestinal inflammation

J Dambacher, F Beigel, K Zitzmann, E N De Toni, B Göke, H M Diepolder, C J Auernhammer, and S Brand

Gut 2009; 58: 1207-1217.
Published Online First: 15 May 2008. doi:10.1136/gut.2007.130112

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Inflammatory bowel disease:

Plexitis as a predictive factor of early postoperative clinical recurrence in Crohn’s disease

H Sokol, V Polin, A Lavergne-Slove, Y Panis, X Treton, X Dray, Y Bouhnik, P Valleur, and P Marteau

Gut 2009; 58: 1218-1225.
Published Online First: 21 July 2009. doi:10.1136/gut.2009.177782

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Colorectal cancer:

MHC Class II alleles in ulcerative colitis-associated colorectal cancer

M M Garrity-Park, E V Loftus, Jr, W J Sandborn, S C Bryant, and T C Smyrk

Gut 2009; 58: 1226-1233.
Published Online First: 26 February 2009. doi:10.1136/gut.2008.166686

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Concomitant mutations and splice variants in KRAS and BRAF demonstrate complex perturbation of the Ras/Raf signalling pathway in advanced colorectal cancer

R Seth, S Crook, S Ibrahem, W Fadhil, D Jackson, and M Ilyas

Gut 2009; 58: 1234-1241.
Published Online First: 26 May 2009. doi:10.1136/gut.2008.159137

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Using CT colonography as a triage technique after a positive faecal occult blood test in colorectal cancer screening

M H Liedenbaum, A F van Rijn, A H de Vries, H M Dekker, M Thomeer, C J van Marrewijk, L Hol, M G W Dijkgraaf, P Fockens, P M M Bossuyt, E Dekker, and J Stoker

Gut 2009; 58: 1242-1249.
Published Online First: 21 July 2009. doi:10.1136/gut.2009.176867

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Expression and localisation of insulin receptor substrate 2 in normal intestine and colorectal tumours. Regulation by intestine-specific transcription factor CDX2

S Modica, A Morgano, L Salvatore, M Petruzzelli, M-T Vanier, R Valanzano, D L Esposito, G Palasciano, I Duluc, J-N Freund, R Mariani-Costantini, and A Moschetta

Gut 2009; 58: 1250-1259.
Published Online First: 15 February 2009. doi:10.1136/gut.2008.158386

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Pancreas:

Transluminal endoscopic necrosectomy after acute pancreatitis: a multicentre study with long-term follow-up (the GEPARD Study)

H Seifert, M Biermer, W Schmitt, C Jürgensen, U Will, R Gerlach, C Kreitmair, A Meining, T Wehrmann, and T Rösch

Gut 2009; 58: 1260-1266.
Published Online First: 11 March 2009. doi:10.1136/gut.2008.163733

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Autoimmune pancreatitis results from loss of TGFβ signalling in S100A4-positive dendritic cells

C S Boomershine, A Chamberlain, P Kendall, A-R Afshar-Sharif, H Huang, M K Washington, W E Lawson, J W Thomas, T S Blackwell, and N A Bhowmick

Gut 2009; 58: 1267-1274.
Published Online First: 21 July 2009. doi:10.1136/gut.2008.170779

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Hepatology:

Low-dose terlipressin plus banding ligation versus low-dose terlipressin alone in the prevention of very early rebleeding of oesophageal varices

G-H Lo, W-C Chen, H-M Wang, C-K Lin, H-H Chan, W-L Tsai, L-C Cheng, H-C Yu, and F-W Tsay

Gut 2009; 58: 1275-1280.
Published Online First: 21 April 2009. doi:10.1136/gut.2008.165910

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High cardiorespiratory fitness is an independent predictor of the reduction in liver fat during a lifestyle intervention in non-alcoholic fatty liver disease

K Kantartzis, C Thamer, A Peter, J Machann, F Schick, C Schraml, A Königsrainer, I Königsrainer, S Kröber, A Niess, A Fritsche, H-U Häring, and N Stefan

Gut 2009; 58: 1281-1288.
Published Online First: 11 December 2008. doi:10.1136/gut.2008.151977

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JournalScan:

JournalScan

Gut 2009; 58: 1289. doi:10.1136/gut.2009.191254

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Recent advances in basic science:

How intestinal epithelial cells tolerise dendritic cells and its relevance to inflammatory bowel disease

M Shale and S Ghosh

Gut 2009; 58: 1291-1299. doi:10.1136/gut.2006.098475

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Neuroimmune mechanisms in postoperative ileus

G E Boeckxstaens and W J de Jonge

Gut 2009; 58: 1300-1311. doi:10.1136/gut.2008.169250

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PostScript:

Principles of clinical gastroenterology

A J M Watson

Gut 2009; 58: 1312. doi:10.1136/gut.2009.179739

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Correction

Gut 2009; 58: 1312. doi:10.1136/gut.2008.174516corr1

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