Skip to main content
Log in

Celiac disease in monozygous twin boys

Asynchronous presentation

  • Case Report
  • Published:
Digestive Diseases and Sciences Aims and scope Submit manuscript

Summary

A 13-year-old boy presented when his weight gain fell behind that of his monozygous twin brother. Following investigation, he was found to have gluten-sensitive enteropathy on jejunal biopsy. Investigation of his symptom-free brother showed biopsy evidence of the condition with changes similar to those of the clinically affected boy. Following treatment with a gluten-free diet, the boys achieved a similar weight after 15 months.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. MacDonald WC, Dobbins WO, Rubin CE: Studies of the familial nature of celiac sprue using biopsy of the small intestine. N Engl J Med 272:448–456, 1965

    PubMed  Google Scholar 

  2. Stokes PL, Asquith P, Cooke WT: Genetics of celiac disease. Clin Gastroenterol 2:547–556, 1973

    Google Scholar 

  3. Mylotte M, Egan-Mitchell B, Fottrel PF, McNicholl B, McCarthy CF: Family studies in celiac disease. Q J Med 171:359–369, 1974

    Google Scholar 

  4. Shipman RT, Williams AL, Kay Rosa, Townley RRW: A family study of celiac disease. Aust NZ J Med 5:250–255, 1975

    Google Scholar 

  5. Ellis A: Celiac disease: Family and twin studies and disease association.In The Genetics and Heterogenecity of Common Gastrointestinal Disorders. JI Rotter, IM Samloff, DL Rimoin (eds). New York, Academic Press, 1980, pp 235–242

    Google Scholar 

  6. Polanco I, Biemond I, Van Leeuwen A, Schreuder I, Khan PM, Guerrero J, D'Amaro J, Vazquez C, Van Rood JJ, Pena AS: Gluten-sensitive enteropathy in Spain: Genetic and environmental factors.In The Genetics of Celiac Disease. RB McConnell (ed), Lancaster, England, MTP Press Ltd, 1981, pp 211–231

    Google Scholar 

  7. Stokes PL, Asquith P, Holmes GKT, Mackintosh P, Cooke WT: Histocompatability antigens associated with adult coeliac disease. Lancet 2:162, 1972 (letter)

    PubMed  Google Scholar 

  8. Keuning JJ, Pena AS, Van Leeuwen A, Van Hooff JP, Van Rood JJ: HLA-DW3 associated with coeliac disease. Lancet 1:506–507, 1976

    Google Scholar 

  9. Littlewood J, Crollick AJ: Childhood coeliac disease is disappearing. Lancet 2:1359, 1980 (letter)

    PubMed  Google Scholar 

  10. Penna FJ, Mota JAD, Roquette MLV, De Carvalho AST, Lemos ATDO, Barbosa ATA, Leao E, Ferreira RA, Castro LDP: Celiac disease in identical twins. Arch Dis Child 54:395–397, 1979

    PubMed  Google Scholar 

  11. Lord C, Macgregor GA: Celiac disease in identical twin infants. Postgrad Med J 57:658–659, 1981

    PubMed  Google Scholar 

  12. Hoffman HN, Wollaeger EE, Greenberg E: Discordance for nontropical sprue (adult celiac disease) in a monozygotic twin pair. Gastroenterology 51:36–42, 1966

    PubMed  Google Scholar 

  13. Walker-Smith JA: Discordance for childhood coeliac disease in monozygous twins. Gut 14:374–375, 1973

    PubMed  Google Scholar 

  14. Jepsen LV, Ullman S: Dermatitis herpetiformis and glutensensitive enteropathy in monozygotic twins. Acta Derm Venereol (Stockh) 60:353–355, 1980

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lee, F.I., Prior, J. & Murray, S.M. Celiac disease in monozygous twin boys. Digest Dis Sci 27, 1137–1140 (1982). https://doi.org/10.1007/BF01391454

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01391454

Keywords

Navigation