Abstract
Background: Tumor size can be measured easily before or during operation with no special tools, but its prognostic use in patients with gastric carcinoma is still unclear.
Methods: Clinicopathologic data of 479 patients who underwent curative operation for gastric carcinoma were studied. The relationship between tumor size and survival of patients was investigated.
Results: The patients were divided into three groups: 182 with tumors measuring <4 cm (group I), 252 with tumors of 4–10 cm (group II), and 45 with tumors of ⩾10 cm (group III). The 10-year survival rates for group I, II, and III patients were 92%, 66%, and 33%, respectively (p<0.01), and the three groups were significantly different with regard to depth of invasion (p<0.01), number and level of lymph node metastasis (p<0.01), and stage of disease (p<0.01). Multivariate analysis indicated that tumor size independently influenced the survival of patients.
Conclusions: Tumor size clinically serves as a simple predictor of tumor progression and survival of patients in gastric carcinoma.
Similar content being viewed by others
References
Bozzetti F, Bonfanti G, Morabito A, et al. A multifactorial approach for the prognosis of patients with carcinoma of the stomach after curative resection.Surg Gynecol Obstet 1986;162:229–34.
Adachi Y, Mori M, Maehara Y, et al. Dukes classification: a valid prognostic indicator for gastric cancer.Gut 1994;35:1368–71.
Adachi Y, Kamakura T, Mori M, et al. Prognostic significance of the number of positive lymph nodes in gastric carcinoma.Br J Surg 1994;81:414–6.
Adachi Y, Oshiro T, Okuyama T, et al. A simple classification of lymph node level in gastric carcinoma.Am J Surg 1995;169:382–5.
Adachi Y, Mori M, Maehara Y, Sugimachi K. Long-term survival after resection for advanced gastric carcinoma.J Clin Gastroenterol 1995;21:208–10.
Haugstvedt TK, Viste A, Eide GE, et al. Norwegian multicentre study of survival and prognostic factors in patients undergoing curative resection for gastric carcinoma.Br J Surg 1993;80:475–8.
Moriguchi S, Maehara Y, Korenaga D, et al. Prediction of survival time after curative surgery for advanced gastric cancer.Eur J Surg Oncol 1992;18:287–92.
Japanese Research Society for Gastric Cancer. The general rules for gastric cancer study in surgery and pathology.Jpn J Surg 1981;11:127–45.
Nakamura K, Ueyama T, Yao T, et al. Pathology and prognosis of gastric carcinoma: findings in 10,000 patients who underwent primary gastrectomy.Cancer 1992;70:1030–7.
Maehara Y, Okuyama T, Moriguchi S, et al. Prophylactic lymph node dissection in patients with advanced gastric cancer promotes increased survival time.Cancer 1992;70:392–5.
Wu CW, Hsieh MJ, Lo SS, et al. Lymph node metastasis from carcinoma of the distal one-third of the stomach.Cancer 1994;73:2059–64.
Maruyama K. The most important prognostic factors for gastric cancer patients.Scand J Gastroenterol 1987;22:63–8.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Adachi, Y., Oshiro, T., Mori, M. et al. Tumor size as a simple prognostic indicator for gastric carcinoma. Annals of Surgical Oncology 4, 137–140 (1997). https://doi.org/10.1007/BF02303796
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02303796