Abstract
A case of heterotopic gastric mucosa in the fundus of the gallbladder is reported. A 23-year-old man, who had been healthy and asymptomatic, visited our hospital because of abnormal findings in a liver enzyme test given during a routine health screening. Ultrasonography demonstrated a highly echogenic polypoid mass in the fundus of the gallbladder. The gallbladder mass was confirmed by both computed tomography and intravenous cholangiogram. After a 10-month follow up, laparoscopic cholecystectomy was performed. Intraoperative touch smear cytology of this lesion revealed class II cells. The surgical specimen revealed a 15×10×5 mm polypoid lesion in the fundus, with no gallstones in the gallbladder. Histologically, the polypoid lesion consisted of both fundic type and pyloric type gastric glands located in the mucosa of the gallbladder. In the literature, 42 cases of heterotopic gastric mucosa of the gallbladder have been reported, only 3 of which, including this present case, were found incidentally, with no apparent symptoms.
Similar content being viewed by others
References
Boyle L, Gallivan MVE, Chun B, et al. Heterotopia of gastric mucosa and liver involving the gallbladder. Arch Pathol Lab Med 1992;116:138–142.
Shimizu H, Yamamoto Y, Sasaki Y, et al. A case of heterotopic gastric mucosa in the gallbladder, with multiple early gastric cancer (in Japanese). Rinshogeka (J Clin Surg) 1984;39:1051–1054.
Sasaki Y, Miyagawa K and Ohuchi A. Heterotopic gastric mucosa in the gallbladder: Report of a case (in Japanese). Tan to Sui 1987;8:1469–1473.
Egyedi L. Case of polypus of gallbladder containing aberrant gastric mucous membrane (in Hungarian). Gyogyaszat (Gyogyastat) 1934;74:596–599.
Vallera DU, Dawson PJ, Path FRC. Gastric heterotopia in the gallbladder, case report and review of literature. Pathol Res Pract 1992;188:49–52.
Lamont N, Winthrop AL, Cole FM, et al. Heterotopic gastric mucosa in the gallbladder: A cause of chronic abdominal pain in a child. J Pediatr Surg 1991;26:1293–1295.
Larsen EH, Diederich PJB, Sorensen FB. Peptic ulcer in the gallbladder. Acta Chir Scand 1985;151:575–576.
Yamamoto M, Murakami H, Ito M, et al. Ectopic gastric mucosa of the gallbladder: Comparison with metaplastic polyp of the gallbladder. Am J Gastroenterol 1989;84:1423–1426.
Young JA, Hughes HE, Lee FD. Evaluation of endoscopic brush and biopsy touch smear cytology and biopsy histology in the diagnosis of carcinoma of the lower oesophagus and cardia. J Clin Pathol 1980;33:811–814.
Tamura K, Masuzawa M, Akiyama T, et al. Touch smear cytology for endoscopic diagnosis of gastric carcinoma. Am J Gastroenterol 1977;67:463–467.
Burger PC. Use of cytological preparations in the frozen section diagnosis of central nervous system neoplasia. Am J Surg Pathol 1985;9:344–354.
Welling RE, Krause RJ, Alamin K. Heterotopic gastric mucosa in the common bile duct. Arch Surg 1970;101:626–627.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Uchiyama, S., Imai, S., Suzuki, T. et al. Heterotopic gastric mucosa of the gallbladder. J Gastroenterol 30, 543–546 (1995). https://doi.org/10.1007/BF02347576
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02347576