Viewpoints in Digestive DiseasesThe pathogenesis of celiac disease☆,☆☆
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Acknowledgements
The authors thank Arthur Tatham, Department of Agricultural Sciences, Bristol University, for useful discussions and comment.
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2006, Journal of AutoimmunityCitation Excerpt :The mechanism proposed here to explain the rising incidence of T1D may be operative in other polygenic diseases. Gluten-sensitive enteropathy is an autoimmune disease that is rising in frequency [47]. Susceptibility HLA markers are HLA-DR3 and HLA-DR7 and excesses of HLA-DR3/DR7 and HLA-DR5/DR7 heterozygotes have been reported in some populations [48,49].
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Address requests for reprints to: Andrew Godkin, M.D., Department of Gastroenterology, John Radcliffe Hospital, Level 2, Headington, Oxford, OX3 9DU England. Fax: (44) 1865-222-998.
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Supported by The Coeliac Trust, British Digestive Foundation, and the Medical Research Council, U.K. (to A.G.)