Elsevier

The Lancet

Volume 343, Issue 8889, 8 January 1994, Pages 85-86
The Lancet

Strictures of ascending colon in cystic fibrosis and high-strength pancreatic enzymes

https://doi.org/10.1016/S0140-6736(94)90817-6Get rights and content

Abstract

We have observed five children with cystic fibrosis, who presented over 2 months, with meconium ileus equivalent that falled to respond to medical management. At surgery, four had a stricture in the ascending colon, and all had histopathological changes of post-ischaemic ulceration repair, with mucosal and submucosal fibrosis. The only common change in the management of these children was a switch from conventional enteric-coated pancreatic enzymes to high-strength products 12–15 months befire presentation.

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There are more references available in the full text version of this article.

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