Pathogenesis of gastrinomas associated with multiple endocrine neoplasia type 1

Gut. 2007 May;56(5):606-7. doi: 10.1136/gut.2006.113985.

Abstract

Deletion of the second allele of the tumour suppressor gene MEN1 is assoiated with development of duodenal gastrin‐secreting microtumours in MEN1

Publication types

  • Comment

MeSH terms

  • Duodenal Neoplasms / genetics*
  • Gastrinoma / genetics*
  • Genetic Predisposition to Disease
  • Humans
  • Multiple Endocrine Neoplasia Type 1 / genetics*
  • Mutation
  • Proto-Oncogene Proteins / genetics*

Substances

  • MEN1 protein, human
  • Proto-Oncogene Proteins