Coeliac-type permanent-tooth enamel defects

Ann Med. 1996 Feb;28(1):9-12. doi: 10.3109/07853899608999067.

Abstract

Systematic and chronologically distributed permanent-tooth so-called coeliac-type enamel defects are highly prevalent both in children and adults with coeliac disease (gluten-sensitive enteropathy) and dermatitis herpetiformis. Coeliac-type enamel defects were also found in healthy first-degree family members of coeliac disease patients. Our family study showed that these persons with the typical defected enamel were genetically similar to coeliac disease patients (A1;B8;DR3). As coeliac disease patients are often clinically silent with no gastrointestinal symptoms, or they complain only of minimal abdominal discomfort, both dentists and physicians could select patients with coeliac-type enamel defects for gastroenterological and dermatological consultations, including serological screening tests and later jejunal mucosal biopsy.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Celiac Disease / complications*
  • Celiac Disease / diagnosis
  • Celiac Disease / genetics
  • Child
  • Child, Preschool
  • Dental Enamel / abnormalities*
  • Dental Enamel Hypoplasia / epidemiology*
  • Dental Enamel Hypoplasia / genetics
  • Dental Enamel Hypoplasia / pathology
  • Dermatitis Herpetiformis / complications
  • Dermatitis Herpetiformis / genetics
  • Humans
  • Infant
  • Prevalence