Triamcinolone improves outcome in Crohn's disease strictures

Dis Colon Rectum. 1997 Feb;40(2):184-6. doi: 10.1007/BF02054985.

Abstract

Purpose: This study was undertaken to examine the effect of local injection of potent steroids on recurrence of Crohn's disease strictures.

Methods: Ten patients with colonic strictures attributable to Crohn's disease were treated by dilation and injection of triamcinolone. Five of them had postoperative strictures.

Results: Patients were followed for 1.5 to 3 years. Two patients required additional dilation and injection of steroids after one year. Eight patients remained well.

Conclusion: Local injection of steroids improves outcome in strictures caused by Crohn's disease.

MeSH terms

  • Administration, Topical
  • Adult
  • Anti-Inflammatory Agents / administration & dosage*
  • Constriction, Pathologic / drug therapy
  • Constriction, Pathologic / therapy
  • Crohn Disease / drug therapy*
  • Crohn Disease / therapy
  • Dilatation / methods
  • Female
  • Glucocorticoids
  • Humans
  • Male
  • Middle Aged
  • Postoperative Complications / drug therapy
  • Postoperative Complications / therapy
  • Triamcinolone / administration & dosage*

Substances

  • Anti-Inflammatory Agents
  • Glucocorticoids
  • Triamcinolone