RT Journal Article
SR Electronic
T1 Action of oral metoclopramide on the gastrooesophageal junction in man
JF Gut
JO Gut
FD BMJ Publishing Group Ltd and British Society of Gastroenterology
SP 380
OP 382
DO 10.1136/gut.14.5.380
VO 14
IS 5
A1 J. B. Dilawari
A1 J. J. Misiewicz
YR 1973
UL http://gut.bmj.com/content/14/5/380.abstract
AB The effect of oral metoclopramide, 10 mg, was studied with intraluminal manometry in 20 patients suffering from symptoms of gastrooesophageal reflux. The drug increased cardiac sphincter pressure and the amplitude of oesophageal peristaltic waves, but gastric motility was stimulated in only half of the patients. The clinical value of these pharmacological effects should be confirmed in therapeutic trials.