TY - JOUR T1 - European consensus conference on faecal microbiota transplantation in clinical practice JF - Gut JO - Gut SP - 569 LP - 580 DO - 10.1136/gutjnl-2016-313017 VL - 66 IS - 4 AU - Giovanni Cammarota AU - Gianluca Ianiro AU - Herbert Tilg AU - Mirjana Rajilić-Stojanović AU - Patrizia Kump AU - Reetta Satokari AU - Harry Sokol AU - Perttu Arkkila AU - Cristina Pintus AU - Ailsa Hart AU - Jonathan Segal AU - Marina Aloi AU - Luca Masucci AU - Antonio Molinaro AU - Franco Scaldaferri AU - Giovanni Gasbarrini AU - Antonio Lopez-Sanroman AU - Alexander Link AU - Pieter de Groot AU - Willem M de Vos AU - Christoph Högenauer AU - Peter Malfertheiner AU - Eero Mattila AU - Tomica Milosavljević AU - Max Nieuwdorp AU - Maurizio Sanguinetti AU - Magnus Simren AU - Antonio Gasbarrini Y1 - 2017/04/01 UR - http://gut.bmj.com/content/66/4/569.abstract N2 - Faecal microbiota transplantation (FMT) is an important therapeutic option for Clostridium difficile infection. Promising findings suggest that FMT may play a role also in the management of other disorders associated with the alteration of gut microbiota. Although the health community is assessing FMT with renewed interest and patients are becoming more aware, there are technical and logistical issues in establishing such a non-standardised treatment into the clinical practice with safety and proper governance. In view of this, an evidence-based recommendation is needed to drive the practical implementation of FMT. In this European Consensus Conference, 28 experts from 10 countries collaborated, in separate working groups and through an evidence-based process, to provide statements on the following key issues: FMT indications; donor selection; preparation of faecal material; clinical management and faecal delivery and basic requirements for implementing an FMT centre. Statements developed by each working group were evaluated and voted by all members, first through an electronic Delphi process, and then in a plenary consensus conference. The recommendations were released according to best available evidence, in order to act as guidance for physicians who plan to implement FMT, aiming at supporting the broad availability of the procedure, discussing other issues relevant to FMT and promoting future clinical research in the area of gut microbiota manipulation. This consensus report strongly recommends the implementation of FMT centres for the treatment of C. difficile infection as well as traces the guidelines of technicality, regulatory, administrative and laboratory requirements. ER -