Density of innervation in regions of the proximal colon in controls and in patients with idiopathic megarectum and idiopathic megacolon
| Longitudinal muscle | Circular muscle | Muscularis mucosae | Lamina propria | |
| Controls | ||||
| S100 | 1 (0–3) | 4 (4) | 3 (3) | 2 (0–3) |
| PGP 9.5 | 1.5 (0–3) | 4 (4) | 3 (3) | 3 (0–3) |
| Idiopathic megarectum | ||||
| S100 | 1 (0–3) | 4 (3–5) | 2 (0, 3)9-150 | 3 (0–3) |
| PGP 9.5 | 1 (0–2) | 4 (3–4) | 2 (0–3) | 3 (0–3) |
| Idiopathic megacolon | ||||
| S100 | 1 (0–3) | 4 (3–4) | 2 (0–3)9-150 | 2 (0–3) |
| PGP 9.5 | 2 (0–3) | 4 (3–4) | 2 (0–3) | 3 (0–3) |
Values given are median (range) score. Scoring system: 0, absent; 1, very sparse; 2, sparse; 3, moderate; 4, dense; 5, very dense. Tissues from three control patients and patients with idiopathic megarectum and those with idiopathic megacolon, all of whom had a dilated proximal colon.
↵9-150 p<0.05.