Major histological findings in non-alcoholic chronic pancreatitis (NACP) compared with alcoholic chronic pancreatitis (ACP)
| Histological finding | NACP | ACP |
| Involved ducts | Especially medium sized interlobular ducts | Large interlobular ducts |
| Periductal inflammation | Conspicuous dense, infiltrating epithelium | Mild scattered, not infiltrating epithelium |
| Lymphocytes | Abundant (T>B) | Sparse (T) |
| Neutrophils | Present | Present in association with calculi |
| Eosinophils | Present | Absent |
| Plasma cells | Present | Present |
| Macrophages | Present | Very rare |
| Dendritic cells | Present | Very rare |
| Calculi | No | Yes |
| Pseudocysts | No | Yes |