Faecal bile acid composition in control subjects and patients with an ileoanal anastomosis
| Parameter | Controls (n=19) | Patients without pouchitis history (n=18) | Patients with pouchitis history (n=6) |
| Cholic acid origin | 2.55 (0.21) | 3.88 (0.81) | 4.53 (1.08) |
| Cholic acid | 0.20 (0.05) | 3.45 (0.80)*** | 4.27 91.04)*** |
| Deoxycholic acid | 1.95 (0.16) | 0.34 (0.11)*** | 0.15 (0.06)*** |
| Epideoxycholic acid | 0.39 (0.06) | 0.09 (0.02)*** | 0.12 (0.03)*** |
| Chenodeoxycholic acid origin | 1.79 (0.17) | 2.74 (0.44) | 3.05 (0.58) |
| Chenodeoxycholic acid | 0.17 (0.04) | 2.15 (0.43)*** | 2.51 (0.58)*** |
| Lithocholic acid | 0.96 (0.11) | 0.14 (0.04)*** | 0.16 (0.03)*** |
| Isolithocholic acid | 0.55 (0.10) | 0.15 (0.03)*** | 0.33 (0.06)† |
| Ursodeoxycholic acid | 0.11 (0.04) | 0.32 (0.06)** | 0.09 (0.04)† |
| Unidentified bile acids | 1.34 (0.12) | 2.74 (0.26)*** | 4.26 (0.71)*** † |
Results expressed in mg/kg/day (mean (SEM)).
9-150 p < 0.05, **p < 0.01, ***p < 0.001 versus control values; †p < 0.05 versus patients without pouchitis.