Prevalence of abdominal symptoms in 333 Danes with epigastric pain at study entry in 1982 and seroprevalence of increased IgM antibodies to H pylori only: multivariate adjusted odds ratios (OR)7-150
| Symptoms and IgM antibodies | Men (n=159) | Women (n=174) | |||||
|---|---|---|---|---|---|---|---|
| n (%) | OR7-150 | 95% CI7-151 | n (%) | OR7-150 | 95% CI7-151 | ||
| Nocturnal pain7-152 | |||||||
| IgG seronegative | 39 (27.9) | 1.0 | 49 (32.5) | 1.0 | |||
| IgG borderline | 9 (69.2) | 5.64 | (1.12–28.39) | 7 (43.8) | 1.88 | (0.64–5.53) | |
| IgG seropositive | 0 (0) | 0.00 | – | 3 (42.9) | 1.53 | (0.31–7.33) | |
| Pain aggravated by drinking | |||||||
| IgG seronegative | 50 (45.5) | 1.0 | 39 (31.2) | 1.0 | |||
| IgG borderline | 9 (75.0) | 3.98 | (0.98–16.15) | 4 (30.8) | 0.89 | (0.16–4.80) | |
| IgG seropositive | 2 (40.0) | 0.93 | (0.14–6.06) | 3 (50.0) | 2.16 | (0.29–16.24) | |
| Nausea | |||||||
| IgG seronegative | 52 (37.1) | 1.0 | 81 (53.6) | 1.0 | |||
| IgG borderline | 10 (76.9) | 5.26 | (1.30–21.33) | 9 (56.3) | 0.77 | (0.22–2.73) | |
| IgG seropositive | 0 (0) | 0.00 | – | 2 (28.6) | 0.60 | (0.09–4.13) | |
| Vomiting | |||||||
| IgG seronegative | 24 (17.1) | 1.0 | 39 (25.8) | 1.0 | |||
| IgG borderline | 7 (53.8) | 4.73 | (1.32–16.93) | 3 (18.8) | 0.34 | (0.07–1.79) | |
| IgG seropositive | 1 (16.7) | 1.09 | (0.10–11.55) | 0 (0) | 0.00 | – | |
| Hearburn7-152 | |||||||
| IgG seronegative | 75 (53.6) | 1.0 | 75 (49.7) | 1.0 | |||
| IgG borderline | 10 (76.9) | 3.95 | (0.65–23.85) | 11 (68.8) | 4.08 | (0.90–18.43) | |
| IgG seropositive | 2 (33.3) | 0.25 | (0.03–2.43) | 3 (42.9) | 0.81 | (0.13–4.95) | |
↵7-150 The upper odds ratio represents the risk of having the symptom in IgM borderline cases compared with IgM seronegative people. The lower odds ratio is the corresponding risk in IgM seropositive people compared with IgM seronegative people.
↵7-151 95% Confidence intervals for multivariate adjusted odds ratios.
↵7-152 Odds ratios were significant when men and women were grouped together (IgM borderline > <IgM seronegative: OR nocturnal pain 2.43 (1.01–5.83), OR heartburn 4.11 (1.48–11.41)).