Table 4

Blood polyamine concentrations and accumulation of radiolabel originating from [14C]putrescine incorporated into the jejunum or small intestine one hour after intraperitoneal injection of [14C]putrescine

Treatment 14C (pmol)Blood polyamines (pmol/ml)
JejunumSmall intestine
LA167 (13)849 (59)182 (76)
LA + AG129 (59)473 (225)** 184 (69)
PHA280 (49)** 1430 (116)** 273 (36)
PHA + AG335 (42)** 1493 (218)** 292 (42)
Ad libitum78 (4)576 (121)180 (80)
48 h fast150 (24)** 955 (61)** 183 (82)
6 h re-fed148 (27)** 1015 (39)** 149 (31)
12 h re-fed103 (18)* 647 (63)172 (24)
  • Data are means (SD) for five rats per treatment.

  • LA, lactalbumin based control diet, containing 10% protein; PHA, kidney bean based diet, in which 5% of the lactalbumin was replaced by bean proteins, providing 42 mg PHA/rat per day; AG, LA or PHA diets containing 6 mg aminoguanidine/day. Rats in these groups were also injected intraperitoneally with 5 mg aminoguanidine in saline every day for three days.

  • Significantly differences between LA or ad libitum: * p < 0.05; ** p < 0.01.