Table 1

 Baseline electrophysiological parameters in specimens grouped by site and associated pathological condition

Specimen site Pathological condition n Isc (μA/cm2) PD (mV) G (mS/cm2)
Small bowel
Non-IBD79  (22)67.0  (4.0)3.5  (0.3)22.9  (0.8)
Crohn’s disease125 (30)63.6 (2.7)3.5 (0.2)19.6 (0.5)**
Large bowel
Non-IBD186 (49)118.4 (3.9)11.6 (0.4)12.2 (0.4)
Crohn’s disease46 (15)146.7 (11.6)** 10.2 (1.3)18.9 (2.0)
Ulcerative colitis34 (9)194.4 (16.2)** 12.7 (0.9)15.1 (0.9)**
  • Values are mean (SEM), n = number of tissues from (n) subjects.**p<0.01 compared with non-IBD specimens. Tissues bathed in chloride free solutions were not included in this analysis.