Characteristics of MMC activity before and after administration of sumatriptan in 12 healthy volunteers
| Variable | Control | Sumatriptan | p Value |
| MMC cycle duration (minutes) | 84.0 (10.6) | 34.0 (6.5) | 0.001 |
| Phase 1 duration (minutes) | 20.5 (4.8) | 17.5 (5.0) | NS |
| Phase 2 duration (minutes) | 61.7 (8.2) | 13.0 (2.2) | 0.0002 |
| Phase 3 duration (minutes) | 5.2 (0.7) | 5.0 (0.5) | NS |
| Phase 3 propagation velocity (cm/min) | 5.9 (1.1) | 5.1 (1.0) | NS |
| Phase 3, percentage gastric onset | 54% (13/24) | 5% (1/21) | 0.005 |
Results are expressed as median (SEM).
The duration of the different phases of the MMC were measured during the cycle preceding the administration of sumatriptan and the first cycle after the administration of sumatriptan at the most distal jejunal channel; the propagation velocity of phase 3 was measured at the jejunal level.