Organ | 13 week old fetus | 17 week old fetus | 23 week old fetus | Adult |
Small intestine | ||||
MUC3 | +++ | +++ | +++ | +++ |
MUC4 | − | − | − | − |
MUC5AC | − | − | − | − |
MUC5B | − | − | − | − |
MUC6 | +/− | +/− | +/− | − |
MUC7 | − | − | − | − |
MUC8 | − | − | − | − |
Colon | ||||
MUC3 | +++ | +++ | +++ | + |
MUC4 | ++ | + | +/− | − |
MUC5AC | − | + | − | − |
MUC5B | − | − | − | +/− |
MUC6 | − | − | − | − |
MUC7 | − | − | − | − |
MUC8 | − | − | − | − |
Pancreas | ||||
MUC3 | +/− | − | − | |
MUC4 | − | − | − | |
MUC5AC | − | − | − | |
MUC5B | − | − | − | |
MUC6 | +++ | +++ | +++ | |
MUC7 | − | − | − | |
MUC8 | − | − | − | |
Stomach | ||||
MUC3 | − | |||
MUC4 | − | |||
MUC5AC | +++ | |||
MUC5B | − | |||
MUC6 | +++ | |||
MUC7 | − | |||
MUC8 | − |
MUC3, MUC4, and MUC5AC are expressed in most epithelial cells in the tissues where transcripts were found. In the stomach MUC5AC mRNA is found in surface mucous cells and MUC6 mRNA in the neck mucous cells. Stomach tissue was not available from 13 and 17 week old fetuses.