Bile flow and biliary lipids before, during and after LDL apheresis
| Before 1 hour | During 1st hour | During 2nd hour | After 2 hours | Significance of change5-150 | |
| Bile flow (ml/15 min) | 4.9 (0.8) | 4.6 (0.6) | 4.6 (0.6) | 4.6 (0.6) | NS |
| Bile acid output (μmol/15 min) | 131 (38) | 98 (17) | 90 (16)5-150 | 93 (17)5-150 | p=0.045 |
| Phospholipid output (μmol/15 min) | 36 (7) | 32 (5) | 29 (4)5-150 | 28 (4)5-150 | p=0.027 |
| Cholesterol output (μmol/15 min) | 7.2 (1.9) | 7.2 (2.2) | 7.0 (2.0) | 6.9 (2.0) | NS |
| Bile acid concentration (μmol/l) | 25 (3) | 21 (3) | 20 (3)5-150 | 20 (3)5-150 | p=0.046 |
| Phospholipid concentration (μmol/l) | 7.3 (0.6) | 7.0 (0.8) | 6.5 (0.7)5-150 | 6.1 (0.6)5-150 | p=0.007 |
| Cholesterol concentration (μmol/l) | 1.5 (0.4) | 1.5 (0.4) | 1.5 (0.3) | 1.5 (0.3) | NS |
| Bile acids (molar %) | 73 (2) | 71 (1) | 71 (1) | 72 (2) | NS |
| Phospholipids (molar %) | 23 (1) | 24 (1) | 24 (1) | 23 (1) | NS |
| Cholesterol (molar %) | 4.4 (1.1) | 4.8 (1) | 5.2 (1) | 5.2 (1.1) | NS |
| Cholesterol saturation (%) | 85 (16) | 92 (18) | 103 (18) | 102 (20) | NS |
↵5-150 In relation to values before apheresis. Analysis of variance with post-hoc least significant difference test.