Data of Jass et al6 showing adenoma numbers in HNPCC and non-HNPCC family members and age of screening
| Total adenomas | Total | ||||
|---|---|---|---|---|---|
| At-risk members of HNPCC families | Controls from necropsies | ||||
| Age <50 | 28 | 6 | 34 | ||
| Age >50 | 24 | 55 | 79 | ||
| Total | 52 | 61 | 113 | ||
χ2 1 = 25.8, p<0.0001
The data are uncorrected for sex or multiple polyps within one individual. Nevertheless, the highly significant χ2 value obtained suggests that an association does exist despite the use of uncorrected data.