Effect of R093877 on stool frequency and consistency
| R093877 1 mg (n=8) | Placebo (n=8) | p Value | R093877 2 mg (n=7) | Placebo (n=7) | p Value | |
| Days urge to defaecate1-150 | 98.2 | 85.7 | 0.041 | 92.9 | 92.9 | 0.99 |
| Days stool passed1-150 | 98.2 | 82.1 | 0.038 | 91.1 | 87.5 | 0.53 |
| No of stools/week | 13.6 | 7.8 | 0.003 | 12.1 | 8.5 | 0.10 |
| Stools loose/watery1-150 | 61.5 | 24.2 | 0.037 | 44.0 | 10.3 | 0.011 |
↵1-150 Expressed as per cents. For the 2 mg dose, the non-compliant volunteer has been excluded.