Influence of the fat content of the meal on postprandial oesophageal acid exposure
| Becker et al4 | Iwakiri et al5 | Penagini et al | |
| Subjects | 10 N + 10 GORD | 20 N | 13 N + 14 GORD |
| Meals | Solid (2.47 MJ) | Liquid (2.09 MJ) | Solid/liquid (3.18 MJ) |
| High fat (61%) v low fat (16%) | High fat (70%) v balanced (25% fat) | High fat (52%)v balanced (24% fat) | |
| Results | |||
| Normal subjects | Increased upright acid exposure | Increased recumbent acid exposure | NS in both sitting and recumbent positions |
| GORD | NS | Not tested | NS in both sitting and recumbent positions |
N, asymptomatic healthy subjects; GORD, patients with erosive oesophagitis or abnormal acid exposure, or both, on 24 hour pH monitoring.