Haplotype | Haplotype count | Haplotype frequency | χ2 | χ2p | Δs | r |
282Y–A*03 | 33 | 0.05 | 15.86 | <0.0001 | 0.41 | 0.22 |
282Y–B*07 | 26 | 0.04 | 0.91 | NS | 0.26 | 0.05 |
282Y–C*0702 | 27 | 0.04 | 1.39 | NS | 0.27 | 0.06 |
282Y–DRB1*15 | 33 | 0.05 | 5.69 | 0.009 | 0.39 | 0.13 |
282Y–DQB1*0602 | 32 | 0.05 | 6.4 | 0.006 | 0.38 | 0.14 |
63D–A*29 | 13 | 0.02 | 6.38 | 0.006 | 0.11 | 0.14 |
Haplotype counts were obtained by counting the number of controls positive for both alleles on a haplotype. Haplotype frequencies were calculated by dividing the number of counted haplotypes by the total number of chromosomes studied (660). Haplotypes are listed as combinations of 282Y or 63D with class I or II alleles for convenience; however, data are identical for haplotypes listed as 63–282–class I/II combinations. This is because 282Y is only found with 63H and 63D with 282C—for example, the 282Y–A*03 date are identical to 63H–282Y–A*03 data. 63H and 282C are not in linkage disequilibrium with class I or II alleles because of the high frequencies of these alleles.
Δs, Δ standardised; r, correlation coefficient (for deviation, see text).