Host or virus parameter
|
Serum RT-PCR negative
|
Serum RT-PCR positive
|
p Value
|
Age (y) | 35.2 (6) | 37.8 (8) | NS |
Sex (M/F) | 7/3 | 61/25 | NS |
Mode of infection | 6 IVDA; 1 post-transfusion; 1 haemophiliac; 2 sporadic | 51 IVDA; 9 post-transfusion; 2 haemophiliac; 24 sporadic | NS |
Duration of infection (median (range)) | 16 (8–22) | 12 (4–42) | NS |
Alcohol | 2 | 13 | NS |
HIV | 0 | 3 | NS |
Hepatitis B virus | 0 | 1 | NS |
Normal ALT | 7 | 8 | <0.001 |
Disease state | 1 Cirrhosis; 9 chronic hepatitis | 9 Cirrhosis; 77 chronic hepatitis | NS |
Histological activity index | 6 (1–13) | 8 (1–14) | NS |
Riba-3 bands | 9 Present (>2 bands); 1 ind | – | NS |
HCV genotype | 4 Genotype 1; 1 genotype 2; 4 genotype 3; 1 genotype 4 | 37 Genotype 1; 11 genotype 2; 32 genotype 3; 6 genotype 4 | NS |