Table 4

Relation between histological findings and chemokine profiles in H pylori positive patients with chronic gastritis

C-X-C chemokineC-C chemokine
IL-8GROαRANTESMIP-1αMIP-1β
PositiveNegativePositiveNegativePositiveNegativePositiveNegativePositiveNegative
No studied
 Antrum39114010272338124010
 Corpus36143812262437133812
MNC infiltration score
 Antrum21.521.52221.5 22
p<0.0001p<0.0005NSp<0.005NS
 Corpus22222221.5 22
NSNSNSp<0.001NS
PMN infiltration score
 Antrum20.520.52222 22
p<0.0001p<0.0005NSNSNS
 Corpus10.5111111 11
p<0.05NSNSNSNS
H pylori density score
 Antrum21212221 21.5
p<0.01p<0.005NSp<0.0001NS
 Corpus21212221 22
p<0.0005p<0.01NSp<0.005NS

  • Positive, specimens positive for the expression of the corresponding chemokine mRNA; negative, specimens negative for the expression of the corresponding chemokine mRNA.

  • Data on MCAF mRNA are not shown as all H pylori positive specimens with chronic gastritis expressed MCAF mRNA.

  • Histological variables were scored from 0 to 3; the median score is shown.

  • Significance was determined using the Mann-Whitney U test.