Taq1 restriction fragment length polymorphism in the interleukin-1β gene: genotype frequencies, allele frequencies and carriage rates in IBD
| Genotype frequency | Allele frequency | Carriage rate | ||||||||
| Taq1 | 1/1 | 1/2 | 2/2 | p3-150 | 1 | 2 | 1 | 2 | ||
| Healthy (n=256) | 57.8 | 35.9 | 6.3 | 75.8 | 24.2 | 93.8 | 42.2 | |||
| CD (n=65) | 72.3 | 23.1 | 4.6 | 0.09 | 83.8 | 16.2 | 95.4 | 27.7 | ||
| CD+PSC (n=74) | 70.3 | 25.7 | 4.1 | 0.139 | 83.1 | 16.9 | 95.9 | 29.7 | ||
| UC (n=54) | 42.6 | 50.0 | 7.4 | 0.118 | 67.6 | 32.4 | 92.6 | 57.4 | ||
| UC +PSC (n=74) | 48.6 | 45.9 | 5.4 | 0.267 | 71.6 | 28.4 | 94.6 | 51.4 | ||
| PSC (n=40) | 65.0 | 32.5 | 2.5 | 0.684 | 81.3 | 18.7 | 97.5 | 35.0 | ||
↵3-150 Disease group v controls.
CD, Crohn’s disease; UC, ulcerative colitis; PSC, primary sclerosing cholangitis.