Intestinal absorption
| Control | Ranitidine | Omeprazole | p Value5-150 | |
| Intestinal absorption | ||||
| Weight (kg/day) | 1.54 (0.11 to 1.93)a | 1.54 (0.39 to 2.78)a | 2.01 (0.82 to 2.98)b | 0.009 |
| Sodium (mmol/day) | −30 (−174 to 18) | 15 (−152 to 39) | −13 (−114 to 17) | 0.10 |
| Potassium (mmol/day) | 42 (19 to 65) | 50 (30 to 73) | 38 (36 to 68) | 0.76 |
| Calcium (mmol/day) | −3 (−20 to 10) | 5 (−6 to 9) | 4 (−2 to 11) | 0.44 |
| Magnesium (mmol/day) | 1 (−1 to 4) | −1 (−9 to 2) | 1 (−1 to 2) | 0.49 |
| Energy (MJ/day) | 4.72 (3.06 to 5.29) | 3.94 (2.55 to 5.98) | 4.11 (3.41 to 5.43) | 0.53 |
| Nitrogen (g/day) | 4.9 (3.4 to 8.1) | 5.7 (2.1 to 6.6) | 2.7 (0.1 to 5.6) | 0.07 |
| Carbohydrate (g/day) | 116.8 (86.1 to 163.8) | 114.8 (72.5 to 160.6) | 137.0 (108.9 to 186.0) | 0.33 |
| Fatty acids (g/day) | 17.8 (5.0 to 25.7) | 13.9 (−3.5 to 25.5) | 17.4 (11.7 to 30.3) | 0.23 |
| Saturated FA (g/day) | 9.9 (3.5 to 15.4) | 7.5 (−2.0 to 15.1) | 10.9 (7.2 to 17.4) | 0.08 |
| Unsaturated FA (g/day) | 7.4 (1.4 to 9.9) | 6.5 (−1.5 to 10.4) | 7.0 (3.6 to 13.1) | 0.26 |
| Differences in absorption | Omeprazole minus ranitidine | Ranitidine minus control | Omeprazole minus control | |
| Weight (kg/day) | 0.17 (0.08 to 0.74)a | 0.46 (−0.11 to 0.71)a | 0.78 (0.09 to 1.42)b | 0.03 |
| Sodium (mmol/day) | 22 (−27 to 63) | 28 (−10 to 92) | 17 (9 to 75) | 0.44 |
| Potassium (mmol/day) | 0 (−14 to 7) | 5 (−6 to 13) | 4 (−9 to 8) | 0.91 |
| Calcium (mmol/day) | −1 (−4 to 3) | 3 (−2 to 15) | 2 (−3 to 9) | 0.32 |
| Magnesium (mmol/day) | 0 (−1 to 1) | −1 (−9 to 1) | 0 (−3 to 2) | 0.74 |
| Energy (MJ/day) | 0.75 (−0.16 to 1.17) | −0.36 (−1.06 to 0.59) | 0.40 (−1.12 to 0.80) | 0.23 |
| Nitrogen (g/day) | 0.0 (−4.2 to 0.6) | −1.1 (−2.4 to 0.6) | −2.7 (−4.8− −1.3) | 0.36 |
| Carbohydrate (g/day) | 24.9 (−11.4 to 60.1) | −6.5 (−27.2 to 17.3) | 17.7 (−9.2 to 32.7) | 0.76 |
| Fatty acids (g/day) | 5.1 (−4.9 to 19.3) | 0.4 (−10.1 to 15.4) | 6.2 (0.8 to 19.5) | 0.53 |
| Saturated FA (g/day) | 4.1 (−1.2 to 11.1) | 0.6 (−7.4 to 8.5) | 3.1 (1.2 to 11.1) | 0.44 |
| Unsaturated FA (g/day) | 1.9 (−2.4 to 11.6) | 1.2 (−2.8 to 6.9) | 4.6 (−0.2 to 7.8) | 0.61 |
Values are median (25 to 75%).
abcSignificant difference between study periods, p<0.05.
↵5-150 Friedman repeated measures analysis of variance on ranks.
FA, fatty acids.