Table 1

Effect of graded doses (pmol/kg/min) of human glucagon-like peptide-1 (GLP-1) or 5% glucose on eating behaviour in 16 healthy male subjects

GLP-1
TreatmentControl0.3750.751.5
Food quantity (g)587 (36)531 (35)1-150 516 (40)1-150 384 (34)***
Calorie intake (kcal)1627 (97)1520 (95)1451 (101)1-150 1107 (84)***
Meal duration (min)38 (3)35 (3)34 (3)1-150 30 (3)1-150
Fluid intake (ml)708 (57)748 (52)689 (48)1-150 584 (45)**
  • Values are expressed as mean (SEM).

  • 1-150 p<0.05, **p<0.01, ***p<0.001 vcontrol.