Dietary details, urokinase activities and proliferative kinetic indexes in the distal colonic mucosa of normal rats
| Experiment no | Dietary supplement1-151 | Urokinase activity (mIU/mg protein) | Crypt column height (cells) | No of metaphase arrests/crypt column | Metaphase index |
| 1 | 10% uncooked potato starch | 10.8 (1.3–40.2)1-150 | 34.4 (32.3–38.4) | 3.9 (2.7–7.1)1-160 | 11.7 (7.8–19.1)1-160 |
| 10% cooked potato starch | 0.7 (0.2–2.5) | 42.4 (25.0–35.6) | 2.0 (1.4–3.4) | 6.4 (4.8–9.6) | |
| 2 | 10% precooked corn flour | 2.2 (1.2–5.5)1-160 | 30.3 (25.9–32.3)1-160 | 1.8 (1.1–2.5) | 6.1 (4.3–7.7) |
| 10% All Bran plus 10% cooked potato starch | 0.8 (0.4–1.7) | 35.4 (31.3–37.8) | 2.7 (2.1–5.4) | 7.8 (6.1–14.3) | |
| 10% All Bran plus 10% uncooked potato starch | 1.6 (1.1–3.9) | 34.8 (32.1–40.4) | 3.1 (1.2–4.2) | 9.0 (3.4–10.4) | |
| 3 | 10% guar gum plus 10% cooked potato starch | 9.7 (2.4–24.6)1-160 | 31.0 (28.3–36.2) | 2.7 (0.9–4.9) | 8.8 (2.9–16.1) |
| 10% wheat bran plus 10% cooked potato starch | 4.9 (1.3–9.9) | 30.5 (26.6–34.3) | 2.1 (1.3–3.4) | 6.9 (4.2–10.5) | |
| 10% wheat bran plus 10% uncooked potato starch | 1.4 (0.7–4.3) | 32.7 (29.4–35.6) | 2.0 (1.2–16.0) | 5.4 (3.6–10.4) | |
| 4 | 10% methylcellulose | 0.4 (0.3–0.6)1-160 | 33.3 (27.8–38.6) | 0.9 (0.4–1.9) | 2.7 (1.2–5.4) |
| 10% wheat bran | 0.7 (0.2–1.2) | 33.3 (32.8–30.4) | 1.2 (1.0–1.7) | 3.3 (2.9–5.1) | |
| 10% oat bran | 1.0 (0.6–1.7) | 32.7 (31.4–35.0) | 1.0 (0.6–2.3) | 3.2 (1.8–7.0) | |
| 10% guar gum | 2.01.1 (0.5–1.5) | 36.3 (32.8–40.5) | 1.3 (0.6–2.7) | 3.8 (1.6–7.1) | |
| 5 | Nil | 1.7 (0.8–2.9) | 28.0 (26.2–30.1)1-160 | 1.5 (0.8–2.5)1-160 | 5.1 (3.1–9.1)1-150 |
| 15% methylcellulose | 2.0 (1.2–3.3) | 35.6 (30.1–38.9) | 2.6 (1.7–3.9) | 7.0 (5.6–11.3) |