Expression of uPAR mRNA and protein in colorectal neoplasms
| Adenoma | Invasive carcinoma | |||||||
|---|---|---|---|---|---|---|---|---|
| Mild dysplasia | Moderate dysplasia | Severe dysplasia | Dukes’ A | Dukes’ B | Dukes’ C | Liver metastasis | ||
| In situ hybridisation (%) | 6/31 (19) | 7/33 (21) | 17/36 (47)1-150 | 21/29 (72)1-151 | 26/28 (93)1-152 | 21/23 (91) | ||
| Immunohistochemistry (%) | 3/31 (10) | 4/33 (12) | 7/36 (19) | 12/29 (41)1-151 | 14/28 (50) | 13/23 (52) | ||
| Northern blot analysis (%) | 3/12 (25) | 4/14 (29) | 5/10 (50) | 5/5 (100) | 5/5 (100) | 5/5 (100) | 3/3 (100) | |
| Western blot analysis (%) | 3/13 (23) | 3/14 (21) | 6/14 (43) | 4/5 (80) | 5/5 (100) | 5/5 (100) | 3/3 (100) | |