IBS+ (n=10) | IBS− (n=19) | Controls (n=18) | |
---|---|---|---|
Mean (SD) age, years | 39.2 (19.1) | 46.8 (16.6) | 30.1 (10.2) |
No of female subjects (%) | 4 (40)† | 7 (37)† | 14 (78) |
No received antibiotics (%) | 8 (80) | 13 (62) | – |
No of positive stool cultures (%) | 6 (60) | 10 (53) | – |
Acute infection biopsy samples | |||
Mean (SD) interval from onset to biopsy, days | 10.6 (18.6) | 5.1 (4.6) | – |
No of patients with macroscopic colitis (%) | 3 (30) | 7 (37) | 0 (0) |
No of biopsy specimens with acute inflammatory changes (%) | 3 (30) | 3 (16) | 0 (0) |
Mean (SD) no of chronic inflammatory cells per hpf | 98.4 (17.4)‡ | 99.8 (35.0)† | 79.1 (16.9) |
Postinfection biopsy samples | |||
Mean (SD) interval from onset to biopsy, days | 106.4 (36.2) | 105.6 (25.9) | – |
No of patients with macroscopic colitis (%) | 0 (0) | 0 (0) | 0 (0) |
No of biopsy specimens with acute inflammatory changes (%) | 2 (20) | 2 (11) | 0 (0) |
Mean (SD) no of chronic inflammatory cells per hpf | 105.7 (23.3)9-150 ‡ | 83.2 (29.4) | 79.1 (16.9) |
↵9-150 p<0.05 versus IBS−; †p<0.05 versus normal controls;‡p<0.01 versus normal controls.